Additive Role of Immune System Infiltration and Angiogenesis in Uveal Melanoma Progression

Nivolumab Plus Ipilimumab for Treatment-Naïve Metastatic Uveal Melanoma: An Open-Label, Multicenter, Phase II Trial by the Spanish Multidisciplinary Melanoma Group (GEM-1402)

(2021) José María Piulats et al.   JOURNAL OF CLINICAL ONCOLOGY

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

(2020) Carlos R. Figueiredo et al.   JOURNAL OF PATHOLOGY

B cells are associated with survival and immunotherapy response in sarcoma

(2020) Florent Petitprez et al.   NATURE

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

PREVALENCE OF MISMATCH REPAIR GENE MUTATIONS IN UVEAL MELANOMA

(2020) Christopher B. Toomey et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

(2020) Richard S. Finn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

(2020) Peter A. Johansson et al.   Nature Communications

Uveal melanoma

(2020) Martine J. Jager et al.   Nature Reviews Disease Primers

Identification of prognostic genes in uveal melanoma microenvironment

(2020) Huan Luo et al.   PLoS One

Uveal Melanoma, Angiogenesis and Immunotherapy, Is There Any Hope?

(2019) Florian Castet et al.   Cancers

Immunological Backbone of Uveal Melanoma: Is There a Rationale for Immunotherapy?

(2019) Ernesto Rossi et al.   Cancers

Comprehensive Benchmarking and Integration of Tumor Microenvironment Cell Estimation Methods

(2019) Alejandro Jiménez-Sánchez et al.   CANCER RESEARCH

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

(2019) David Liu et al.   NATURE MEDICINE

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations

(2018) David Tamborero et al.   CLINICAL CANCER RESEARCH

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa

(2018) Kabir A. Khan et al.   Nature Reviews Clinical Oncology

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

Identification of novel chemotherapeutic strategies for metastatic uveal melanoma

(2017) Paolo Fagone et al.   Scientific Reports

Metastatic disease from uveal melanoma: treatment options and future prospects

(2016) Richard D Carvajal et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Clinical outcomes in metastatic uveal melanoma treated with PD-1 and PD-L1 antibodies

(2016) Alain P. Algazi et al.   CANCER

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

PRAME as an Independent Biomarker for Metastasis in Uveal Melanoma

(2016) M. G. Field et al.   CLINICAL CANCER RESEARCH

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

(2015) W. Peng et al.   Cancer Discovery

Systemic treatment of metastatic uveal melanoma: review of literature and future perspectives

(2015) Kristina Buder et al.   Cancer Medicine

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Relative survival of patients with uveal melanoma managed in a single center

(2012) Josep Maria Caminal et al.   MELANOMA RESEARCH

Mda-9/Syntenin Is Expressed in Uveal Melanoma and Correlates with Metastatic Progression

(2012) Rosaria Gangemi et al.   PLoS One

Descriptive epidemiology of malignant mucosal and uveal melanomas and adnexal skin carcinomas in Europe

(2011) S. Mallone et al.   EUROPEAN JOURNAL OF CANCER

Metastatic uveal melanoma

(2011) Francesc Pons et al.   MELANOMA RESEARCH

High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

(2010) C. Laurent et al.   CANCER RESEARCH

Immune escape mechanisms of intraocular tumors

(2009) Jerry Y. Niederkorn   PROGRESS IN RETINAL AND EYE RESEARCH