DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

Results and challenges of immune checkpoint inhibitors in colorectal cancer

(2018) Sheik Emambux et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer

(2018) Varun Sasidharan Nair et al.   Clinical Epigenetics

Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells

(2017) Varun Sasidharan Nair et al.   IMMUNOLOGY AND CELL BIOLOGY

Immune Checkpoints as a Target for Colorectal Cancer Treatment

(2017) Alessandro Passardi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intratumoral FoxP3+Helios+ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer

(2017) Azharuddin Sajid Syed Khaja et al.   Frontiers in Immunology

PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes

(2016) Matthew W Rosenbaum et al.   MODERN PATHOLOGY

DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases

(2016) Varun Sasidharan Nair et al.   MOLECULES AND CELLS

Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases

(2015) Lydia G. M. van der Geest et al.   CLINICAL & EXPERIMENTAL METASTASIS

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

Loss of 5-hydroxymethylcytosine in cancer: Cause or consequence?

(2014) Gabriella Ficz et al.   GENOMICS

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Connections between TET proteins and aberrant DNA modification in cancer

(2014) Yun Huang et al.   TRENDS IN GENETICS

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

(2013) William A. Pastor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Epigenetics and colorectal cancer

(2011) Victoria Valinluck Lao et al.   Nature Reviews Gastroenterology & Hepatology

Epigenetic changes in colorectal cancer

(2011) Yan Jia et al.   Chinese Journal of Cancer

Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21

(2009) Sarah Derks et al.   CARCINOGENESIS

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE