DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-19
DOI
10.1038/s41467-019-12159-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
- (2019) Arie B. Brinkman et al. Nature Communications
- Genomic and Functional Approaches to Understanding Cancer Aneuploidy
- (2018) Alison M. Taylor et al. CANCER CELL
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- DNA methylation loss in late-replicating domains is linked to mitotic cell division
- (2018) Wanding Zhou et al. NATURE GENETICS
- Method of the Year 2017: Organoids
- (2018) NATURE METHODS
- The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
- (2018) David A. Schaer et al. Cell Reports
- Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis
- (2018) Michäel Duruisseaux et al. Lancet Respiratory Medicine
- CDK4/6 inhibition triggers anti-tumour immunity
- (2017) Shom Goel et al. NATURE
- The Encyclopedia of DNA elements (ENCODE): data portal update
- (2017) Carrie A Davis et al. NUCLEIC ACIDS RESEARCH
- Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
- (2017) Teresa Davoli et al. SCIENCE
- Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
- (2017) Whijae Roh et al. Science Translational Medicine
- Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers
- (2017) Chan-Young Ock et al. Nature Communications
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
- (2017) Jiehui Deng et al. Cancer Discovery
- Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
- (2017) Pornpimol Charoentong et al. Cell Reports
- Combining Epigenetic and Immunotherapy to Combat Cancer
- (2016) Katherine B. Chiappinelli et al. CANCER RESEARCH
- Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
- (2016) Jianjun Gao et al. CELL
- Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
- (2016) Christoph Bock et al. NATURE BIOTECHNOLOGY
- Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy
- (2016) Nadeem Riaz et al. NATURE GENETICS
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing
- (2016) Eric Talevich et al. PLoS Computational Biology
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR
- (2015) Hui Yang et al. Nature Protocols
- Cell Lineage Analysis in Human Brain Using Endogenous Retroelements
- (2015) Gilad D. Evrony et al. NEURON
- Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites
- (2015) Seung-Tae Lee et al. NUCLEIC ACIDS RESEARCH
- The odds of immunotherapy success
- (2015) M. M. Gubin et al. SCIENCE
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
- (2015) E. M. Van Allen et al. SCIENCE
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
- (2014) Volker Hovestadt et al. NATURE
- Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells
- (2014) Zohar Shipony et al. NATURE
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- The UCSC Genome Browser database: 2015 update
- (2014) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors
- (2014) Winston Timp et al. Genome Medicine
- Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array
- (2013) Magda E Price et al. Epigenetics & Chromatin
- ENCODE Data in the UCSC Genome Browser: year 5 update
- (2012) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
- (2011) G. C. Hon et al. GENOME RESEARCH
- Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
- (2011) Benjamin P Berman et al. NATURE GENETICS
- A revised nomenclature for transcribed human endogenous retroviral loci
- (2011) Jens Mayer et al. Mobile DNA
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Human DNA methylomes at base resolution show widespread epigenomic differences
- (2009) Ryan Lister et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More