Solvent-free synthesis of 3,5-isoxazoles via 1,3-dipolar cycloaddition of terminal alkynes and hydroxyimidoyl chlorides over Cu/Al2O3 surface under ball-milling conditions

Mechanisms and Substituent Effects of Metal-Free Bioorthogonal Reactions

(2021) Titas Deb et al.   CHEMICAL REVIEWS

Sustainability Assessment of Mechanochemistry by Using the Twelve Principles of Green Chemistry

(2021) Karen J. Ardila‐Fierro et al.   ChemSusChem

Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy

(2020) Lukas Gorecki et al.   PHARMACOLOGY & THERAPEUTICS

Iterative Assembly of Nitrile Oxides and Ynamides: Synthesis of Isoxazoles and Pyrroles

(2019) Changwei Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Environmentally Benign and Scalable Preparation of Diethyl Furoxan-3,4-dicarboxylate Using Silver Carbonate as a Nitrile Oxide Generator

(2019) Mao-Xi Zhang et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Harnessing the TEMPO-Catalyzed Aerobic Oxidation for Machetti–De Sarlo Reaction toward Sustainable Synthesis of Isoxazole Libraries

(2019) Murugan Vadivelu et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Cascade Cyclization Reactions of Diazo Compounds with tert-Butyl Nitrite and Alkynes: One-Pot Synthesis of Isoxazoles

(2019) Xue-Di Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

The recent progress of isoxazole in medicinal chemistry

(2018) Jie Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

From Oxiranes to Oligomers: Architectures of US FDA Approved Pharmaceuticals Containing Oxygen Heterocycles

(2018) Michael D. Delost et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

(2018) Joseph L. Howard et al.   Chemical Science

Catalyst- and solvent-free mechanochemical synthesis of isoxazoles from N-hydroxybenzimidoyl chlorides and enamino carbonyl compounds

(2018) Hui Xu et al.   TETRAHEDRON

Isoxazole ring as a useful scaffold in a search for new therapeutic agents

(2017) Angelika Sysak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzisoxazole: a privileged scaffold for medicinal chemistry

(2017) K. P. Rakesh et al.   MedChemComm

Synthesis of 3,5-Disubstituted Isoxazoles Containing Privileged Substructures with a Diverse Display of Polar Surface Area

(2017) Mingi Kim et al.   ACS Combinatorial Science

Copper-catalyzed aerobic oxidative C–O bond formation for the synthesis of 3,5-disubstituted isoxazoles from enone oximes

(2017) Yadong Sun et al.   RSC Advances

Metrics of Green Chemistry and Sustainability: Past, Present, and Future

(2017) Roger A. Sheldon   ACS Sustainable Chemistry & Engineering

Copper nitrate-mediated chemo- and regioselective annulation from two different alkynes: a direct route to isoxazoles

(2017) Yingying Li et al.   Organic Chemistry Frontiers

Water-Assisted Nitrile Oxide Cycloadditions: Synthesis of Isoxazoles and Stereoselective Syntheses of Isoxazolines and 1,2,4-Oxadiazoles

(2016) Chatchai Kesornpun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

(2016) Davin Tan et al.   CHEMICAL COMMUNICATIONS

Cu(I) catalyzed microwave assisted telescopic synthesis of 3,5-disubstituted isoxazoles in green media

(2016) D R Meena et al.   TETRAHEDRON LETTERS

Mechanochemistry: A Force of Synthesis

(2016) Jean-Louis Do et al.   ACS Central Science

Recent Developments in the Synthesis and Reactivity of Isoxazoles: Metal Catalysis and Beyond

(2015) Feng Hu et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanochemical Synthesis and Antioxidant Activity of Curcumin-Templated Azoles

(2015) Daisy R. Sherin et al.   ARCHIV DER PHARMAZIE

Recent Advances of Catalytic Asymmetric 1,3-Dipolar Cycloadditions

(2015) Takuya Hashimoto et al.   CHEMICAL REVIEWS

Metal-free DBU promoted regioselective synthesis of isoxazoles and isoxazolines

(2015) Shabber Mohammed et al.   RSC Advances

Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents

(2015) Juana M. Pérez et al.   ACS Sustainable Chemistry & Engineering

Copper(0) Nanoparticles in Click Chemistry: Synthesis of 3,5-Disubstituted Isoxazoles

(2014) T. M. Vishwanatha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of functional groups as acetyl-lysine mimetics for BET bromodomain inhibition

(2014) Phillip P. Sharp et al.   MedChemComm

Recent advances and applications of Glaser coupling employing greener protocols

(2014) K. S. Sindhu et al.   RSC Advances

Freedom: a copper-free, oxidant-free and solvent-free palladium catalysed homocoupling reaction

(2013) Longrui Chen et al.   GREEN CHEMISTRY

Mechanosynthesis of ultra-small monodisperse amine-stabilized gold nanoparticles with controllable size

(2013) Monika J. Rak et al.   GREEN CHEMISTRY

Investigation of facet effects on the catalytic activity of Cu2O nanocrystals for efficient regioselective synthesis of 3,5-disubstituted isoxazoles

(2013) Kaushik Chanda et al.   Nanoscale

Hypervalent Iodine Catalyzed Generation of Nitrile Oxides from Oximes and their Cycloaddition with Alkenes or Alkynes

(2013) Akira Yoshimura et al.   ORGANIC LETTERS

Montmorillonite clay Cu(II) catalyzed domino one-pot multicomponent synthesis of 3,5-disubstituted isoxazoles

(2013) Sandip B. Bharate et al.   TETRAHEDRON LETTERS

Desymmetrisation of aromatic diamines and synthesis of non-symmetrical thiourea derivatives by click-mechanochemistry

(2012) Vjekoslav Štrukil et al.   CHEMICAL COMMUNICATIONS

Solvent-free one-pot synthesis of 1,2,3-triazole derivatives by the ‘Click’ reaction of alkyl halides or aryl boronic acids, sodium azide and terminal alkynes over a Cu/Al2O3surface under ball-milling

(2012) Nirmalya Mukherjee et al.   GREEN CHEMISTRY

One-Pot Synthesis of 3,5-Disubstituted Isoxazoles from Alkynes and Activated Nitroalkanes

(2012) Li Lin et al.   Asian Journal of Organic Chemistry

A novel method for the preparation of Cu/Al2O3 nanocomposite

(2011) Yueli Wen et al.   APPLIED SURFACE SCIENCE

Fast, ligand- and solvent-free copper-catalyzed click reactions in a ball mill

(2011) Rico Thorwirth et al.   CHEMICAL COMMUNICATIONS

Synthesis of isoxazoles by hypervalent iodine-induced cycloaddition of nitrile oxides to alkynes

(2011) Anup M. Jawalekar et al.   CHEMICAL COMMUNICATIONS

Mechanochemistry: opportunities for new and cleaner synthesis

(2011) Stuart L. James et al.   CHEMICAL SOCIETY REVIEWS

Fast, Ligand- and Solvent-Free Synthesis of 1,4-Substituted Buta-1,3-diynes by Cu-Catalyzed Homocoupling of Terminal Alkynes in a Ball Mill

(2011) Robert Schmidt et al.   CHEMISTRY-A EUROPEAN JOURNAL

Energetic assessment of the Suzuki–Miyaura reaction: a curtate life cycle assessment as an easily understandable and applicable tool for reaction optimization

(2009) Franziska Schneider et al.   GREEN CHEMISTRY

Copper Catalysts for Soot Oxidation: Alumina versus Perovskite Supports

(2008) F. E. López-Suárez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The Suzuki−Miyaura Reaction under Mechanochemical Conditions§

(2008) Franziska Schneider et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT