Dietary Fibers: Effects, Underlying Mechanisms and Possible Role in Allergic Asthma Management

Diet Modifications in Primary Prevention of Asthma. Where Do We Stand?

(2021) Barbara Sozańska et al.   Nutrients

The basic immunology of asthma

(2021) Hamida Hammad et al.   CELL

Association of Allergic Diseases and Related Conditions with Dietary Fiber Intake in Korean Adults

(2021) Hoyoung Lee et al.   International Journal of Environmental Research and Public Health

One march, many paths: Insights into allergic march trajectories

(2021) Stanislaw J. Gabryszewski et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

A review of epigenetic changes in asthma: methylation and acetylation

(2021) Mojgan Sheikhpour et al.   Clinical Epigenetics

Tolerance development in cow’s milk–allergic infants receiving amino acid–based formula: A randomized controlled trial

(2021) Pantipa Chatchatee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis

(2021) Vadim Pivniouk et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Gata3 enhancer necessary for ILC2 development and function

(2021) Darshan N. Kasal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Butyrate inhibits human mast cell activation via epigenetic regulation of FcεRI‐mediated signaling

(2020) Jelle Folkerts et al.   ALLERGY

The Role of Lung and Gut Microbiota in the Pathology of Asthma

(2020) Weronika Barcik et al.   IMMUNITY

Allergic Endotypes and Phenotypes of Asthma

(2020) Nicole Akar-Ghibril et al.   Journal of Allergy and Clinical Immunology-In Practice

Dietary cellulose prevents gut inflammation by modulating lipid metabolism and gut microbiota

(2020) Yeji Kim et al.   Gut Microbes

Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress

(2020) Irma Tindemans et al.   JOURNAL OF CLINICAL INVESTIGATION

SCFA: mechanisms and functional importance in the gut

(2020) Camille Martin-Gallausiaux et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The Relationship between the Infant Gut Microbiota and Allergy. The Role of Bifidobacterium breve and Prebiotic Oligosaccharides in the Activation of Anti-Allergic Mechanisms in Early Life

(2020) Bożena Cukrowska et al.   Nutrients

Dietary fiber metabolites regulate innate lymphoid cell responses

(2020) Ali Sepahi et al.   Mucosal Immunology

Impact of prebiotics on immune response: from the bench to the clinic

(2020) Radha Pujari et al.   IMMUNOLOGY AND CELL BIOLOGY

Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells

(2020) Levi B. Richards et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

(2019) Maik Luu et al.   Nature Communications

Group 2 Innate Lymphoid Cells in Human Respiratory Disorders

(2019) Esmee K. van der Ploeg et al.   Journal of Innate Immunity

Proinflammatory Pathways in the Pathogenesis of Asthma

(2019) R. Stokes Peebles et al.   CLINICS IN CHEST MEDICINE

Blocking histone deacetylase activity as a novel target for epithelial barrier defects in allergic rhinitis

(2019) Brecht Steelant et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival

(2019) Anna Theiler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis

(2019) Ting Wen et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbes, metabolites, and the gut–lung axis

(2019) Anh Thu Dang et al.   Mucosal Immunology

Transcription factors and 3D genome conformation in cell-fate decisions

(2019) Ralph Stadhouders et al.   NATURE

A specific synbiotic-containing amino acid-based formula restores gut microbiota in non-IgE mediated cow’s milk allergic infants: a randomized controlled trial

(2019) Harm Wopereis et al.   Clinical and Translational Allergy

Association between dietary fiber intake and asthma (symptoms and control): results from the French national e-cohort NutriNet-Santé

(2019) Roland M. Andrianasolo et al.   BRITISH JOURNAL OF NUTRITION

Advances in epigenetics link genetics to the environment and disease

(2019) Giacomo Cavalli et al.   NATURE

Mast Cells and Their Progenitors in Allergic Asthma

(2019) Erika Méndez-Enríquez et al.   Frontiers in Immunology

Soluble fibre supplementation with and without a probiotic in adults with asthma: A 7-day randomised, double blind, three way cross-over trial

(2019) Rebecca McLoughlin et al.   EBioMedicine

Regional Diversity of the Gastrointestinal Microbiome

(2019) Kristina Martinez-Guryn et al.   Cell Host & Microbe

Role of IL-17 in asthma pathogenesis and its implications for the clinic

(2019) Rakhee K Ramakrishnan et al.   Expert Review of Respiratory Medicine

Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation

(2019) Gavin Lewis et al.   Frontiers in Immunology

Tracing IgE-Producing Cells in Allergic Patients

(2019) Julia Eckl-Dorna et al.   Cells

Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome

(2018) Ece A. Mutlu et al.   ENVIRONMENTAL POLLUTION

Regulation of type 2 innate lymphoid cell–dependent airway hyperreactivity by butyrate

(2018) Christina Li-Ping Thio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility

(2018) Ralph Stadhouders et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma

(2018) Alberto Papi et al.   LANCET

GM-CSF intrinsically controls eosinophil accumulation in allergic airway inflammation

(2018) Samuel Philip Nobs et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early Dietary Intervention with a Mixture of Prebiotic Oligosaccharides Reduces the Incidence of Allergic Manifestations and Infections during the First Two Years of Life

(2018) Sertac Arslanoglu et al.   JOURNAL OF NUTRITION

Early-Life Formation of the Microbial and Immunological Environment of the Human Airways

(2018) Céline Pattaroni et al.   Cell Host & Microbe

The group 2 innate lymphoid cell (ILC2) regulatory network and its underlying mechanisms

(2018) Hiroki Kabata et al.   IMMUNOLOGICAL REVIEWS

Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review

(2018) Petra Zimmermann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epigenetic Regulation via Altered Histone Acetylation Results in Suppression of Mast Cell Function and Mast Cell-Mediated Food Allergic Responses

(2018) Dylan Krajewski et al.   Frontiers in Immunology

The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma

(2018) Kim A. T. Verheijden et al.   Frontiers in Immunology

Regulation of bronchial epithelial barrier integrity by type 2 cytokines and histone deacetylases in asthmatic patients

(2017) Paulina Wawrzyniak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

(2017) A Cait et al.   Mucosal Immunology

Dietary fibre in Europe: current state of knowledge on definitions, sources, recommendations, intakes and relationships to health

(2017) Alison M. Stephen et al.   NUTRITION RESEARCH REVIEWS

A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants

(2017) David C A Candy et al.   PEDIATRIC RESEARCH

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma

(2017) Isabel Halnes et al.   Nutrients

Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models

(2017) D. Betty Lew et al.   Journal of Immunology Research

The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells

(2017) Meike Kespohl et al.   Frontiers in Immunology

β2→1-Fructans Modulate the Immune System In Vivo in a Microbiota-Dependent and -Independent Fashion

(2017) Floris Fransen et al.   Frontiers in Immunology

Regulatory T Cells in Allergy and Asthma

(2017) Elena Martín-Orozco et al.   Frontiers in Pediatrics

Dietary Supplementation with Fructooligosaccharides Attenuates Airway Inflammation Related to House Dust Mite Allergen in Mice

(2017) A. Yasuda et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation

(2016) Neil C. Williams et al.   BRITISH JOURNAL OF NUTRITION

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Lung-gut cross-talk: evidence, mechanisms and implications for the mucosal inflammatory diseases

(2016) M. K. Tulic et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Early-life respiratory infections and asthma development

(2016) Avraham Beigelman et al.   Current Opinion in Allergy and Clinical Immunology

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice

(2016) Bobby W. S. Li et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite

(2016) André Ballesteros-Tato et al.   IMMUNITY

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

Emerging pathogenic links between microbiota and the gut–lung axis

(2016) Kurtis F. Budden et al.   NATURE REVIEWS MICROBIOLOGY

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

Th9 and other IL-9-producing cells in allergic asthma

(2016) Sonja Koch et al.   Seminars in Immunopathology

The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation

(2016) Shinji Toki et al.   THORAX

Dietary Fiber Intake Regulates Intestinal Microflora and Inhibits Ovalbumin-Induced Allergic Airway Inflammation in a Mouse Model

(2016) Zhiyu Zhang et al.   PLoS One

The Role of Short-Chain Fatty Acids, Produced by Anaerobic Bacteria, in the Cystic Fibrosis Airway

(2015) Bojana Mirković et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dietary changes in migrant adolescents with increasing length of stay in Australia and associated risk of wheeze – a retrospective, cross sectional study

(2015) Lisa G. Wood et al.   BMC Pediatrics

Microbiota Metabolite Regulation of Host Immune Homeostasis: A Mechanistic Missing Link

(2015) S. Steinmeyer et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The development of allergic inflammation in a murine house dust mite asthma model is suppressed by synbiotic mixtures of non-digestible oligosaccharides and Bifidobacterium breve M-16V

(2015) K. A. T. Verheijden et al.   EUROPEAN JOURNAL OF NUTRITION

Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth

(2015) Peyman Ghorbani et al.   EUROPEAN RESPIRATORY JOURNAL

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites

(2015) Jonathan M. Coquet et al.   IMMUNITY

Inflammation-Induced Expression of the Alarmin Interleukin 33 Can Be Suppressed by Galacto-Oligosaccharides

(2015) Kim A.T. Verheijden et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

DNA methylation and childhood asthma in the inner city

(2015) Ivana V. Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory T Cell Depletion Abolishes the Protective Effect of Dietary Galacto-Oligosaccharides on Eosinophilic Airway Inflammation in House Dust Mite–Induced Asthma in Mice

(2015) Kim AT Verheijden et al.   JOURNAL OF NUTRITION

An epigenome-wide association study of total serum immunoglobulin E concentration

(2015) Liming Liang et al.   NATURE

Innate immunological function of TH2 cells in vivo

(2015) Liying Guo et al.   NATURE IMMUNOLOGY

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

(2015) Alison N. Thorburn et al.   Nature Communications

Regulation of lung immunity and host defense by the intestinal microbiota

(2015) Derrick R. Samuelson et al.   Frontiers in Microbiology

Asthma

(2015) Stephen T. Holgate et al.   Nature Reviews Disease Primers

Bacillus subtilis KCTC 11782BP-Produced Alginate Oligosaccharide Effectively Suppresses Asthma via T-Helper Cell Type 2-Related Cytokines

(2015) Mi-Ae Bang et al.   PLoS One

The combination of Bifidobacterium breve with non-digestible oligosaccharides suppresses airway inflammation in a murine model for chronic asthma

(2014) Seil Sagar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

GATA-3 Function in Innate and Adaptive Immunity

(2014) Irma Tindemans et al.   IMMUNITY

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

(2014) J Park et al.   Mucosal Immunology

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

(2014) Grégory Seumois et al.   NATURE IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Breast milk, microbiota and intestinal immune homeostasis

(2014) W. Allan Walker et al.   PEDIATRIC RESEARCH

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Gut Microbe-Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice

(2014) J. J. Faith et al.   Science Translational Medicine

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Asthma genetics and personalised medicine

(2014) Deborah A Meyers et al.   Lancet Respiratory Medicine

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

(2013) Alison Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract

(2013) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

The biodiversity hypothesis and allergic disease: world allergy organization position statement

(2013) Tari Haahtela et al.   World Allergy Organization Journal

Butyrate increases IL-23 production by stimulated dendritic cells

(2012) Bradford E. Berndt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE–antigen complex-stimulated RBL-2H3 cells and asthma model mice

(2012) Mi Ja Chung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

(2012) Erwin G Zoetendal et al.   ISME Journal

Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases

(2012) Susan L. Prescott   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

G protein-coupled receptors for energy metabolites as new therapeutic targets

(2012) Clara C. Blad et al.   NATURE REVIEWS DRUG DISCOVERY

Investigation of the association between dietary intake, disease severity and airway inflammation in asthma

(2012) Bronwyn S. Berthon et al.   RESPIROLOGY

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age

(2011) Hans Bisgaard et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms of allergen-specific immunotherapy

(2011) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergic Asthma: Influence of Genetic and Environmental Factors

(2011) Anil B. Mukherjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse microbial exposure – Consequences for vaccine development

(2011) Bengt Björkstén   VACCINE

Synbiotics reduce allergen-induced T-helper 2 response and improve peak expiratory flow in allergic asthmatics

(2010) M. A. Van De Pol et al.   ALLERGY

Synbiotics prevent asthma-like symptoms in infants with atopic dermatitis

(2010) L. B. van der Aa et al.   ALLERGY

Establishment and development of lactic acid bacteria and bifidobacteria microbiota in breast-milk and the infant gut

(2010) G. Solís et al.   ANAEROBE

Effect of a new synbiotic mixture on atopic dermatitis in infants: a randomized-controlled trial

(2010) L. B. van der Aa et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Predictors of remitting, periodic, and persistent childhood asthma

(2010) Ronina A. Covar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways

(2010) S Navarro et al.   Mucosal Immunology

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of adjuvant and adjuvant-free murine experimental asthma models

(2009) M. L. Conrad et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Effects of short chain fatty acids on effector mechanisms of neutrophils

(2008) Marco A. R. Vinolo et al.   CELL BIOCHEMISTRY AND FUNCTION

Mouse models of allergic asthma: acute and chronic allergen challenge

(2008) A. T. Nials et al.   Disease Models & Mechanisms