Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs

Evaluating totipotency using criteria of increasing stringency

(2021) Eszter Posfai et al.   NATURE CELL BIOLOGY

Opportunities and Challenges with Stem Cell-Based Embryo Models

(2021) Janet Rossant et al.   Stem Cell Reports

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states

(2020) Alex Neagu et al.   NATURE CELL BIOLOGY

Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro

(2020) Gianluca Amadei et al.   DEVELOPMENTAL CELL

Single-Cell RNA-Seq Reveals Cellular Heterogeneity of Pluripotency Transition and X Chromosome Dynamics during Early Mouse Development

(2019) Shangli Cheng et al.   Cell Reports

A single-cell molecular map of mouse gastrulation and early organogenesis

(2019) Blanca Pijuan-Sala et al.   NATURE

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse

(2019) Aitana Perea-Gomez et al.   Scientific Reports

BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis

(2019) Hyung-Seok Kim et al.   eLife

NicheNet: modeling intercellular communication by linking ligands to target genes

(2019) Robin Browaeys et al.   NATURE METHODS

Choice of factors and medium impinge on success of ESC to TSC conversion

(2019) Franziska Kaiser et al.   PLACENTA

Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo

(2018) Carla Mulas et al.   DEVELOPMENT

Blastocyst-like structures generated solely from stem cells

(2018) Nicolas C. Rivron et al.   NATURE

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures

(2018) Berna Sozen et al.   NATURE CELL BIOLOGY

Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells

(2018) Richard Patryk Ngondo et al.   Stem Cell Reports

Regulation of Placental Development and Its Impact on Fetal Growth—New Insights From Mouse Models

(2018) Laura Woods et al.   Frontiers in Endocrinology

Single-cell analysis reveals lineage segregation in early post-implantation mouse embryos

(2017) Jing Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

(2017) Hisham Mohammed et al.   Cell Reports

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

(2017) Eszter Posfai et al.   eLife

A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation

(2016) S. Nestorowa et al.   BLOOD

Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation

(2016) Geng Chen et al.   GENOME RESEARCH

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Id2 Mediates Differentiation of Labyrinthine Placental Progenitor Cell Line, SM10

(2016) Kaisa Selesniemi et al.   STEM CELLS AND DEVELOPMENT

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

(2016) Alessandro Fiorenzano et al.   Nature Communications

Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation

(2016) Mohan Malleshaiah et al.   Cell Reports

Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts

(2015) Caroline Kubaczka et al.   Cell Stem Cell

Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration

(2015) Amit Kumar et al.   DEVELOPMENTAL BIOLOGY

Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner

(2015) Martyn Donnison et al.   DEVELOPMENTAL BIOLOGY

AVE protein expression and visceral endoderm cell behavior during anterior–posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression

(2015) Hideharu Hoshino et al.   DEVELOPMENTAL BIOLOGY

Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

(2015) Sissy E. Wamaitha et al.   GENES & DEVELOPMENT

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

(2014) Thorsten Boroviak et al.   NATURE CELL BIOLOGY

Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo

(2014) I. Bedzhov et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification

(2013) J. A. Hoffman et al.   DEVELOPMENT

The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo

(2013) S. Nowotschin et al.   GENES & DEVELOPMENT

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells

(2013) Kathy K Niakan et al.   Nature Protocols

Cell-Surface Proteomics Identifies Lineage-Specific Markers of Embryo-Derived Stem Cells

(2012) Peter J. Rugg-Gunn et al.   DEVELOPMENTAL CELL

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm

(2011) Agnieszka Paca et al.   DEVELOPMENTAL BIOLOGY

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

Bone morphogenetic protein 4 signaling regulates development of the anterior visceral endoderm in the mouse embryo

(2010) Miguel L. Soares et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

Pkd1 and Pkd2 Are Required for Normal Placental Development

(2010) Miguel A. Garcia-Gonzalez et al.   PLoS One

Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1

(2009) Susanne Weber et al.   BIOLOGY OF REPRODUCTION

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

The molecular machinery of germ line specification

(2009) Ben Ewen-Campen et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Sall4 Regulates Distinct Transcription Circuitries in Different Blastocyst-Derived Stem Cell Lineages

(2008) Chin Yan Lim et al.   Cell Stem Cell

Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways

(2008) Hitomi Suzuki et al.   DEVELOPMENTAL BIOLOGY

The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

(2008) Gloria S. Kwon et al.   DEVELOPMENTAL CELL

Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis

(2008) Devorah C. Goldman et al.   MECHANISMS OF DEVELOPMENT