Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo

(2016) Melanie D. White et al.   CELL

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

(2016) Mubeen Goolam et al.   CELL

Early preimplantation cells expressing Cdx2 exhibit plasticity of specification to TE and ICM lineages through positional changes

(2016) Yayoi Toyooka et al.   DEVELOPMENTAL BIOLOGY

Asymmetric division of contractile domains couples cell positioning and fate specification

(2016) Jean-Léon Maître et al.   NATURE

Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo

(2015) Chaminda R. Samarage et al.   DEVELOPMENTAL CELL

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Limited predictive value of blastomere angle of division in trophectoderm and inner cell mass specification

(2014) T. Watanabe et al.   DEVELOPMENT

Inhibition of RHO–ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst

(2014) Kanako Kono et al.   DEVELOPMENTAL BIOLOGY

Notch and Hippo Converge on Cdx2 to Specify the Trophectoderm Lineage in the Mouse Blastocyst

(2014) Teresa Rayon et al.   DEVELOPMENTAL CELL

Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing

(2014) Fernando H. Biase et al.   GENOME RESEARCH

Bayesian approach to single-cell differential expression analysis

(2014) Peter V Kharchenko et al.   NATURE METHODS

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo

(2014) Sarah J. L. Graham et al.   Nature Communications

HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

(2014) Eryn Wicklow et al.   PLoS Genetics

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

TEAD4 establishes the energy homeostasis essential for blastocoel formation

(2013) K. J. Kaneko et al.   DEVELOPMENT

Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation

(2013) C. Lorthongpanich et al.   GENES & DEVELOPMENT

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

(2013) Yusuke Ohnishi et al.   NATURE CELL BIOLOGY

Accounting for technical noise in single-cell RNA-seq experiments

(2013) Philip Brennecke et al.   NATURE METHODS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Single-Cell Profiling of Epigenetic Modifiers Identifies PRDM14 as an Inducer of Cell Fate in the Mammalian Embryo

(2013) Adam Burton et al.   Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

4D imaging reveals a shift in chromosome segregation dynamics during mouse pre-implantation development

(2012) Kazuo Yamagata et al.   CELL CYCLE

Generation and live imaging of an endogenous Cdx2 reporter mouse line

(2012) Katie McDole et al.   GENESIS

Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment

(2012) P. Home et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo

(2011) J. B. Grabarek et al.   DEVELOPMENT

Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates

(2011) Katie McDole et al.   DEVELOPMENTAL BIOLOGY

Oct4 kinetics predict cell lineage patterning in the early mammalian embryo

(2011) Nicolas Plachta et al.   NATURE CELL BIOLOGY

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

(2011) Fuchou Tang et al.   PLoS One

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2

(2010) A. Ralston et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin

(2010) R. O. Stephenson et al.   DEVELOPMENT

Individual blastomeres of 16- and 32-cell mouse embryos are able to develop into foetuses and mice

(2010) Andrzej K. Tarkowski et al.   DEVELOPMENTAL BIOLOGY

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

Making the blastocyst: lessons from the mouse

(2010) Katie Cockburn et al.   JOURNAL OF CLINICAL INVESTIGATION

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

(2009) Kevin R. Brown et al.   BIOINFORMATICS

Cross-regulation of the Nanog and Cdx2 promoters

(2009) Lingyi Chen et al.   CELL RESEARCH

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data

(2009) Daniel Ramsköld et al.   PLoS Computational Biology

Blastomeres of the mouse embryo lose totipotency after the fifth cleavage division: Expression of Cdx2 and Oct4 and developmental potential of inner and outer blastomeres of 16- and 32-cell embryos

(2008) Aneta Suwińska et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT