Gum Arabic supplementation prevents loss of learning and memory through stimulation of mitochondrial function in the hippocampus of type 2 diabetic rats

The Effect of Gum Arabic (Acacia senegal) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial

(2021) Amjad H. Jarrar et al.   Nutrients

Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects

(2021) Riley Larson et al.   Nutrients

SDF-1α Gene-Activated Collagen Scaffold Restores Pro-Angiogenic Wound Healing Features in Human Diabetic Adipose-Derived Stem Cells

(2021) Ashang L. Laiva et al.   Biomedicines

Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation

(2021) Bin Han et al.   Genome Medicine

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Role of gut microbiota in type 2 diabetes pathophysiology

(2020) Manoj Gurung et al.   EBioMedicine

Type 2 Diabetes Mellitus: A Review of Multi-Target Drugs

(2020) Angelica Artasensi et al.   MOLECULES

A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons

(2020) L.J. McMeekin et al.   NEUROSCIENCE

Implication of the gut microbiome composition of type 2 diabetic patients from northern China

(2020) Qian Li et al.   Scientific Reports

Anti-neuroinflammatory Effect of Short-Chain Fatty Acid Acetate against Alzheimer’s Disease via Upregulating GPR41 and Inhibiting ERK/JNK/NF-κB

(2020) Jiaming Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Neuroprotective Effect of Syringic Acid by Modulation of Oxidative Stress and Mitochondrial Mass in Diabetic Rats

(2020) Marzieh Rashedinia et al.   Biomed Research International

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Microglial regional heterogeneity and its role in the brain

(2019) Yun-Long Tan et al.   MOLECULAR PSYCHIATRY

A randomized controlled trial on the efficacy of resistant dextrin, as functional food, in women with type 2 diabetes: Targeting the hypothalamic–pituitary–adrenal axis and immune system

(2018) Mahdieh Abbasalizad Farhangi et al.   CLINICAL NUTRITION

LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

(2018) Chun-Lei Han et al.   Journal of Neuroinflammation

Effect of Gum Arabic (Acacia Senegal) supplementation on visceral adiposity index (VAI) and blood pressure in patients with type 2 diabetes mellitus as indicators of cardiovascular disease (CVD): a randomized and placebo-controlled clinical trial

(2018) Rasha Babiker et al.   Lipids in Health and Disease

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice

(2018) Stephanie M. Matt et al.   Frontiers in Immunology

Metformin Alleviated the Neuronal Oxidative Stress in Hippocampus of Rats under Single Prolonged Stress

(2017) Jiangang Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Type 2 diabetes

(2017) Sudesna Chatterjee et al.   LANCET

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

(2017) et al.   Nutrients

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection

(2017) Hojin Kang et al.   Oncotarget

Understanding the Physics of Functional Fibers in the Gastrointestinal Tract: An Evidence-Based Approach to Resolving Enduring Misconceptions about Insoluble and Soluble Fiber

(2017) Johnson W. McRorie et al.   Journal of the Academy of Nutrition and Dietetics

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42and Phospho-Tau May Abet Alzheimer Development

(2016) Mini Sajan et al.   DIABETES

Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association

(2016) Sheri R. Colberg et al.   DIABETES CARE

Oral supplementation of 2′-fucosyllactose during lactation improves memory and learning in rats

(2016) Elena Oliveros et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hypoglycemic effect of formulation containing hydroethanolic extract of Calophyllum brasiliense in diabetic rats induced by streptozotocin

(2016) Helison de Oliveira Carvalho et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Hypoglycemic effect of formulation containing hydroethanolic extract of Calophyllum brasiliense in diabetic rats induced by streptozotocin

(2016) Helison de Oliveira Carvalho et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

(2015) Cristina Carvalho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The prebiotics 3′Sialyllactose and 6′Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut–brain axis

(2015) Andrew J. Tarr et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary fibre and incidence of type 2 diabetes in eight European countries: the EPIC-InterAct Study and a meta-analysis of prospective studies

(2015)   DIABETOLOGIA

Effects of a human milk oligosaccharide, 2′-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents

(2015) Enrique Vázquez et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat

(2015) Ghupurjan Gheni et al.   Journal of Diabetes Research

Increased protein aggregation in Zucker Diabetic Fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide

(2014) Fatemeh Talaei et al.   BMC CELL BIOLOGY

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sex differences in learning and memory following short-term dietary restriction in the rat

(2014) Ebrahim Rajab et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Effect of Gum Arabic on Glucose Levels and Microbial Short-Chain Fatty Acid Production in White Rice Porridge Model and Mixed Grain Porridge Model

(2014) Jie-Lun Hu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Validation and implementation of a novel high-throughput behavioral phenotyping instrument for mice

(2014) Jesse Brodkin et al.   JOURNAL OF NEUROSCIENCE METHODS

Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-d-aspartate receptor subunits and d-serine

(2013) Helene M. Savignac et al.   NEUROCHEMISTRY INTERNATIONAL

Probiotics treatment improves diabetes-induced impairment of synaptic activity and cognitive function: Behavioral and electrophysiological proofs for microbiome–gut–brain axis

(2013) S. Davari et al.   NEUROSCIENCE

The role of microglia in adult hippocampal neurogenesis

(2013) Carmelina Gemma et al.   Frontiers in Cellular Neuroscience

Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms

(2013) Amer Kamal et al.   EXPERIMENTAL BRAIN RESEARCH

A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat

(2013) Norihide Yokoi et al.   Journal of Diabetes Research

‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition

(2012) Rahul Agrawal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dietary Fiber for the Treatment of Type 2 Diabetes Mellitus: A Meta-Analysis

(2012) R. E. Post et al.   Journal of the American Board of Family Medicine

Effects of gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial

(2012) Rasha Babiker et al.   Nutrition Journal

Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines

(2012) Aiwu Cheng et al.   Nature Communications

Deficiency of Antinociception and Excessive Grooming Induced by Acute Immobilization Stress in Per1 Mutant Mice

(2011) Jing Zhang et al.   PLoS One

Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis

(2010) Je-Seong Won et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Downregulation of Mouse Intestinal Na+-coupled Glucose Transporter SGLT1 by Gum Arabic (Acacia Senegal)

(2010) Omaima Nasir et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of long term ingestion of gum arabic on the adipose tissues of female mice

(2010) Kazunari Ushida et al.   FOOD HYDROCOLLOIDS

Inflammaging: The driving force in osteoporosis?

(2010) P. Lencel et al.   MEDICAL HYPOTHESES

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia

(2009) Rahul Agrawal et al.   NEUROPHARMACOLOGY

The regulatory and scientific approach to defining gum arabic (Acacia senegal and Acacia seyal) as a dietary fibre

(2007) Glyn O. Phillips et al.   FOOD HYDROCOLLOIDS