Topographic Cues Guiding Cell Polarization via Distinct Cellular Mechanosensing Pathways

Surface-Directed Self-Epitaxial Crystallization of Poly(ε-caprolactone) from Isotropic to Highly Orientated Lamellae

(2020) Wei Liu et al.   MACROMOLECULES

Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cells

(2020) Mei Ding et al.   Scientific Reports

Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling

(2020) Anouk R. Killaars et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anisotropic Nanoscale Presentation of Cell Adhesion Ligand Enhances the Recruitment of Diverse Integrins in Adhesion Structures and Mechanosensing-Dependent Differentiation of Stem Cells

(2019) Siu Hong Dexter Wong et al.   ADVANCED FUNCTIONAL MATERIALS

Tissue self-organization based on collective cell migration by contact activation of locomotion and chemotaxis

(2019) Taihei Fujimori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anisotropic Ligand Nanogeometry Modulates the Adhesion and Polarization State of Macrophages

(2019) Heemin Kang et al.   NANO LETTERS

Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination

(2019) Heemin Kang et al.   Nature Communications

Subcellular Control over Focal Adhesion Anisotropy, Independent of Cell Morphology, Dictates Stem Cell Fate

(2019) Maria D. Cabezas et al.   ACS Nano

Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia

(2019) Iskra Yanakieva et al.   JOURNAL OF CELL BIOLOGY

Microchannel Stiffness and Confinement Jointly Induce the Mesenchymal-Amoeboid Transition of Cancer Cell Migration

(2019) Meng Wang et al.   NANO LETTERS

Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions

(2019) Rishita Changede et al.   NATURE MATERIALS

Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions

(2019) Danielle Park et al.   NATURE MATERIALS

Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion

(2019) N. O. Alieva et al.   Nature Communications

Surface Roughness and Substrate Stiffness Synergize To Drive Cellular Mechanoresponse

(2019) Yong Hou et al.   NANO LETTERS

Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

(2018) Li He et al.   NATURE

Human brain organoids on a chip reveal the physics of folding

(2018) Eyal Karzbrun et al.   Nature Physics

Control of Mechanotransduction by Molecular Clutch Dynamics

(2018) Alberto Elosegui-Artola et al.   TRENDS IN CELL BIOLOGY

Assessment of Polysaccharides from Mycelia of genus Ganoderma by Mid-Infrared and Near-Infrared Spectroscopy

(2018) Yuhan Ma et al.   Scientific Reports

An In Situ Reversible Heterodimeric Nanoswitch Controlled by Metal-Ion-Ligand Coordination Regulates the Mechanosensing and Differentiation of Stem Cells

(2018) Heemin Kang et al.   ADVANCED MATERIALS

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration

(2017) Arja Ray et al.   Nature Communications

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

(2017) Jeong-Ki Kim et al.   Nature Communications

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

(2017) Tobias G. Kapp et al.   Scientific Reports

A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity

(2016) Angie M. Y. Shum et al.   ADVANCED MATERIALS

Dynamically Regulated Ag Nanowire Arrays for Detecting Molecular Information of Substrate-Induced Stretched Cell Growth

(2016) Zhen Zhang et al.   ADVANCED MATERIALS

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

(2016) Su-Jin Heo et al.   eLife

Insight On Colorectal Carcinoma Infiltration by Studying Perilesional Extracellular Matrix

(2016) Manuela Nebuloni et al.   Scientific Reports

Biologics for tendon repair

(2015) Denitsa Docheva et al.   ADVANCED DRUG DELIVERY REVIEWS

Universal polymer coatings and their representative biomedical applications

(2015) Qiang Wei et al.   Materials Horizons

Protein Interactions with Polymer Coatings and Biomaterials

(2014) Qiang Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interplay of matrix stiffness and protein tethering in stem cell differentiation

(2014) Jessica H. Wen et al.   NATURE MATERIALS

Cell-Material Interactions Revealed Via Material Techniques of Surface Patterning

(2013) Xiang Yao et al.   ADVANCED MATERIALS

Engineering cell alignment in vitro

(2013) Yuhui Li et al.   BIOTECHNOLOGY ADVANCES

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Microwrinkled Conducting Polymer Interface for Anisotropic Multicellular Alignment

(2012) Francesco Greco et al.   ACS Applied Materials & Interfaces

Fine-Tuning the Degree of Stem Cell Polarization and Alignment on Ordered Arrays of High-Aspect-Ratio Nanopillars

(2012) Michael A. Bucaro et al.   ACS Nano

High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts

(2011) Andrew F. Adler et al.   BIOMATERIALS

Directed 3D cell alignment and elongation in microengineered hydrogels

(2010) Hug Aubin et al.   BIOMATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Proliferation of aligned mammalian cells on laser-nanostructured polystyrene

(2008) Esther Rebollar et al.   BIOMATERIALS

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY