Intravesical delivery of KDM6A-mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer
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Title
Intravesical delivery of KDM6A-mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 119, Issue 7, Pages e2112696119
Publisher
Proceedings of the National Academy of Sciences
Online
2022-02-08
DOI
10.1073/pnas.2112696119
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Note: Only part of the references are listed.- Significance of KDM6A mutation in bladder cancer immune escape
- (2021) Xingxing Chen et al. BMC CANCER
- A Thermostable mRNA Vaccine against COVID-19
- (2020) Na-Na Zhang et al. CELL
- siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice
- (2020) Wei Tao et al. Science Translational Medicine
- Tumor Cell Dissociation Removes Malignant Bladder Tumors
- (2020) Qunqun Bao et al. Chem
- Paving the Road for RNA Therapeutics
- (2020) Niels Dammes et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- A materials-science perspective on tackling COVID-19
- (2020) Zhongmin Tang et al. Nature Reviews Materials
- Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma
- (2020) Jiaqing Yi et al. CANCER LETTERS
- Insights from nanotechnology in COVID-19 treatment
- (2020) Zhongmin Tang et al. Nano Today
- Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes
- (2019) Li-Ming Gan et al. Nature Communications
- Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- (2019) Abhishek A. Chakraborty et al. SCIENCE
- UTX Mutations in Human Cancer
- (2019) Lu Wang et al. CANCER CELL
- Contingencies of UTX/KDM6A Action in Urothelial Carcinoma
- (2019) Alexander Lang et al. Cancers
- Therapeutic mRNA delivery to leukocytes
- (2019) Yasmin Granot-Matok et al. JOURNAL OF CONTROLLED RELEASE
- Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency
- (2019) Brian Truong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aberrant N-cadherin expression in cancer
- (2019) Zhan-Qi Cao et al. BIOMEDICINE & PHARMACOTHERAPY
- Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition
- (2019) Na Kong et al. Science Translational Medicine
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors
- (2018) Jaclyn Andricovich et al. CANCER CELL
- Multicenter Prospective Phase II Trial of Neoadjuvant Dose-Dense Gemcitabine Plus Cisplatin in Patients With Muscle-Invasive Bladder Cancer
- (2018) Gopa Iyer et al. JOURNAL OF CLINICAL ONCOLOGY
- UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs
- (2018) Malgorzata Gozdecka et al. NATURE GENETICS
- UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma
- (2018) Xiaoxi Li et al. Nature Communications
- Progress and challenges towards targeted delivery of cancer therapeutics
- (2018) Daniel Rosenblum et al. Nature Communications
- X chromosome protects against bladder cancer in females via aKDM6A-dependent epigenetic mechanism
- (2018) Satoshi Kaneko et al. Science Advances
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA
- (2018) Mohammad Ariful Islam et al. Nature Biomedical Engineering
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes
- (2018) Nuphar Veiga et al. Nature Communications
- Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy
- (2017) Xiaoding Xu et al. NANO LETTERS
- Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
- (2017) Lian Dee Ler et al. Science Translational Medicine
- Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo
- (2017) Xi Zhu et al. Theranostics
- PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
- (2016) Jung Soo Suk et al. ADVANCED DRUG DELIVERY REVIEWS
- Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias
- (2016) Andrew Dunford et al. NATURE GENETICS
- Kabuki syndrome genesKMT2DandKDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development
- (2015) Peter M. Van Laarhoven et al. HUMAN MOLECULAR GENETICS
- Synthetic mRNAs for manipulating cellular phenotypes: an overview
- (2015) Elgar Susanne Quabius et al. New Biotechnology
- Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
- (2015) Xi Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functionalized Mesoporous Silica Nanoparticles with Mucoadhesive and Sustained Drug Release Properties for Potential Bladder Cancer Therapy
- (2014) Quan Zhang et al. LANGMUIR
- Genetic landscape of esophageal squamous cell carcinoma
- (2014) Yi-Bo Gao et al. NATURE GENETICS
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
- (2014) Thomas S. Ligon et al. PLoS One
- Driver mutations of cancer epigenomes
- (2014) David M. Roy et al. Protein & Cell
- Single-cell mRNA transfection studies: Delivery, kinetics and statistics by numbers
- (2013) Carolin Leonhardt et al. Nanomedicine-Nanotechnology Biology and Medicine
- The mutational landscape of adenoid cystic carcinoma
- (2013) Allen S Ho et al. NATURE GENETICS
- Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
- (2012) M. R. Kang et al. CANCER RESEARCH
- Branched peptides as novel tumor-targeting agents for bladder cancer
- (2012) Andrea Minervini et al. Expert Review of Anticancer Therapy
- Deletion of KDM6A, a Histone Demethylase Interacting with MLL2, in Three Patients with Kabuki Syndrome
- (2011) Damien Lederer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- In vivo Evaluation of Mucoadhesive Nanoparticulate Docetaxel for Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer
- (2011) C. Mugabe et al. CLINICAL CANCER RESEARCH
- UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program
- (2011) Seunghee Lee et al. DEVELOPMENTAL CELL
- MicroRNA-200c Represses Migration and Invasion of Breast Cancer Cells by Targeting Actin-Regulatory Proteins FHOD1 and PPM1F
- (2011) S. Jurmeister et al. MOLECULAR AND CELLULAR BIOLOGY
- Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
- (2011) Ignacio Varela et al. NATURE
- Intravesical drug delivery: Challenges, current status, opportunities and novel strategies
- (2010) Shruti GuhaSarkar et al. JOURNAL OF CONTROLLED RELEASE
- Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery
- (2009) Lichen Yin et al. BIOMATERIALS
- Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
- (2009) Massimiliano Mazzone et al. CELL
- Bladder cancer
- (2009) Donald S Kaufman et al. LANCET
- Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
- (2009) Gijs van Haaften et al. NATURE GENETICS
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- Current prospects for mRNA gene delivery
- (2008) Ayako Yamamoto et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Cadherins and cancer: how does cadherin dysfunction promote tumor progression?
- (2008) A Jeanes et al. ONCOGENE
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