Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

(2015) Lot Snijders Blok et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

(2015) Ronan Chaligné et al.   GENOME RESEARCH

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma

(2015) Lu Jiang et al.   NATURE GENETICS

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

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The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Genomic landscape of paediatric adrenocortical tumours

(2015) Emilia M. Pinto et al.   Nature Communications

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Absent CNKSR2 causes seizures and intellectual, attention, and language deficits

(2014) Andrea K. Vaags et al.   ANNALS OF NEUROLOGY

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

(2014) Joni Van der Meulen et al.   BLOOD

X-chromosome inactivation in development and cancer

(2014) Ronan Chaligné et al.   FEBS LETTERS

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

(2014) Daniel W. Bellott et al.   NATURE

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

(2014) Panagiotis Ntziachristos et al.   NATURE

Origins and functional evolution of Y chromosomes across mammals

(2014) Diego Cortez et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

(2014) Lars A Forsberg et al.   NATURE GENETICS

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

(2014) Andrew A Lane et al.   NATURE GENETICS

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance

(2014) Akinori Yoda et al.   NATURE MEDICINE

Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease

(2014) Hao Wu et al.   NEURON

Smoking is associated with mosaic loss of chromosome Y

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MLL2 and KDM6A mutations in patients with Kabuki syndrome

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Cancer statistics, 2013

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Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

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RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

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Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome

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Loss of Y-chromosome does not correlate with age at onset of head and neck carcinoma: a case-control study

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Enigmatic sex disparities in cancer incidence

(2012) Gustaf Edgren et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Cancer cells preferentially lose small chromosomes

(2012) Pascal H.G. Duijf et al.   INTERNATIONAL JOURNAL OF CANCER

Gene Survival and Death on the Human Y Chromosome

(2012) Melissa A. Wilson Sayres et al.   MOLECULAR BIOLOGY AND EVOLUTION

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

(2012) G. G. Welstead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

(2012) Karl B. Shpargel et al.   PLoS Genetics

Demographic variation in incidence of adult glioma by subtype, United States, 1992-2007

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A cross-species comparison of escape from X inactivation in Eutheria: implications for evolution of X chromosome inactivation

(2011) Shafagh Al Nadaf et al.   CHROMOSOMA

X-chromosome inactivation: molecular mechanisms from the human perspective

(2011) Christine Yang et al.   HUMAN GENETICS

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Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

(2011) Peter S. Hammerman et al.   Cancer Discovery

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

PHF6 mutations in T-cell acute lymphoblastic leukemia

(2010) Pieter Van Vlierberghe et al.   NATURE GENETICS

Sex Disparities in Cancer Incidence by Period and Age

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice

(2009) C. Patrat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete

(2008) Colette M. Johnston et al.   PLoS Genetics