Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer

PCTR1 enhances repair and bacterial clearance in skin wounds.

(2021) Brian E. Sansbury et al.   AMERICAN JOURNAL OF PATHOLOGY

γδ T/Interleukin-17A Contributes to the Effect of Maresin Conjugates in Tissue Regeneration 1 on Lipopolysaccharide-Induced Cardiac Injury

(2021) Yi Yang et al.   Frontiers in Immunology

Maresin conjugates in tissue regeneration 1 prevents lipopolysaccharide-induced cardiac dysfunction through improvement of mitochondrial biogenesis and function

(2020) Yi Yang et al.   BIOCHEMICAL PHARMACOLOGY

MCTR1 enhances the resolution of lipopolysaccharide‐induced lung injury through STAT6‐mediated resident M2 alveolar macrophage polarization in mice

(2020) Qian Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

PCTR1 improves pulmonary edema fluid clearance through activating the sodium channel and lymphatic drainage in lipopolysaccharide‐induced ARDS

(2020) Pu‐hong Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neuromodulation, Specialized Proresolving Mediators, and Resolution of Pain

(2020) Xueshu Tao et al.   Neurotherapeutics

Specialized pro-resolving mediator network: an update on production and actions

(2020) Nan Chiang et al.   Essays in Biochemistry

Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury

(2020) Juri Kim et al.   MOLECULAR NEUROBIOLOGY

Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

(2020) Benjamin Schwarz et al.   JOURNAL OF IMMUNOLOGY

HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis

(2019) Tianye Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolvin the clot: DVT resolution through RvD4

(2019) Michael Holinstat   BLOOD

Liquid chromatography-coupled mass spectrometry analysis of glutathione conjugates of oxygenated polyunsaturated fatty acids

(2019) Stefanie Liening et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Biosynthetic metabolomes of cysteinyl-containing immunoresolvents

(2019) Charlotte C. Jouvene et al.   FASEB JOURNAL

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration

(2018) Xavier de la Rosa et al.   AMERICAN JOURNAL OF PATHOLOGY

The Formation and Function of Granulomas

(2018) Antonio J. Pagán et al.   Annual Review of Immunology

Leukotriene biosynthetic enzymes as therapeutic targets

(2018) Jesper Z. Haeggström   JOURNAL OF CLINICAL INVESTIGATION

Frontline Science: Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation

(2018) Jeremy W. Winkler et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

(2017) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

First total synthesis of pro-resolving and tissue-regenerative resolvin sulfido-conjugates

(2017) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia

(2016) Jennifer K. Colby et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

(2016) Jeremy W. Winkler et al.   Scientific Reports

Critical role of phospholipase A2group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection

(2015) Rahul Vijay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resolving Resolvins

(2013) Jesper Z. Haeggström et al.   CHEMISTRY & BIOLOGY

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY