Biosynthetic metabolomes of cysteinyl-containing immunoresolvents

Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration

(2018) Xavier de la Rosa et al.   AMERICAN JOURNAL OF PATHOLOGY

Combatting Sepsis: A Public Health Perspective

(2018) Raymund B Dantes et al.   CLINICAL INFECTIOUS DISEASES

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Key roles for lipid mediators in the adaptive immune response

(2018) Parker F. Duffney et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukotriene biosynthetic enzymes as therapeutic targets

(2018) Jesper Z. Haeggström   JOURNAL OF CLINICAL INVESTIGATION

Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair

(2018) Jason Hellmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain

(2018) Gang Chen et al.   NEURON

Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation

(2018) Paul C. Norris et al.   Scientific Reports

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

(2017) Charles N. Serhan et al.   MOLECULAR ASPECTS OF MEDICINE

Effects of postnatal omega-3 fatty acid supplementation on offspring pro-resolving mediators of inflammation at 6 months and 5 years of age: A double blind, randomized controlled clinical trial

(2017) V.H.L. See et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Long chain fatty acids and related pro-inflammatory, specialized pro-resolving lipid mediators and their intermediates in preterm human milk during the first month of lactation

(2017) D.T. Robinson et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Recent advances in clinical development of leukotriene B4 pathway drugs

(2017) L. Bhatt et al.   SEMINARS IN IMMUNOLOGY

First total synthesis of pro-resolving and tissue-regenerative resolvin sulfido-conjugates

(2017) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation

(2016) Sesquile Ramon et al.   AMERICAN JOURNAL OF PATHOLOGY

Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

(2016) Krishnaraj S. Rathod et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

(2016) Jesmond Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specialised pro-resolving mediators of inflammation in inflammatory arthritis

(2016) Anne E. Barden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

(2016) Gabrielle Fredman et al.   Nature Communications

Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3

(2016) Jesmond Dalli et al.   PLoS One

Enhanced Resolution of Hyperoxic Acute Lung Injury as a result of Aspirin Triggered Resolvin D1 Treatment

(2015) Ruan Cox et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS

(2015) Ai Sasaki et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Activation of autophagy in macrophages by pro-resolving lipid mediators

(2015) Patricia Prieto et al.   Autophagy

Specialized proresolving mediators (SPMs) inhibit human B-cell IgE production

(2015) Nina Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

(2015) Jesmond Dalli et al.   FASEB JOURNAL

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

(2015) S. Rossi et al.   MEDIATORS OF INFLAMMATION

Resolvin Infectious Inflammation by Targeting the Host Response

(2015) Craig R. Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Total synthesis of pro-resolving and tissue-regenerative Protectin sulfido-conjugates

(2015) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation

(2015) Mauro Perretti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Lipoxin Generation Is Related to Soluble Epoxide Hydrolase Activity in Severe Asthma

(2014) Emiko Ono et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Resolvin D1 Attenuates Polyinosinic-Polycytidylic Acid–Induced Inflammatory Signaling in Human Airway Epithelial Cells via TAK1

(2014) Hsi-Min Hsiao et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1, a Metabolite of Omega-3 Polyunsaturated Fatty Acid, Decreases Post-Myocardial Infarct Depression

(2014) Kim Gilbert et al.   Marine Drugs

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection

(2014) J. Dalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment

(2013) James F. Markworth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma

(2013) Zhen-Zhong Xu et al.   ANNALS OF NEUROLOGY

Catalytic Characterization of Human Microsomal Glutathione S-Transferase 2: Identification of Rate-Limiting Steps

(2013) Shabbir Ahmad et al.   BIOCHEMISTRY

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype

(2013) Jesmond Dalli et al.   FASEB JOURNAL

Crystal Structures of Leukotriene C4Synthase in Complex with Product Analogs

(2013) Damian Niegowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: A randomized trial

(2013) Christopher E. Ramsden et al.   PAIN

Orchestration of Metabolism by Macrophages

(2012) Subhra K. Biswas et al.   Cell Metabolism

Resolvins D1, D2, and Other Mediators of Self-Limited Resolution of Inflammation in Human Blood following n-3 Fatty Acid Supplementation

(2012) E. Mas et al.   CLINICAL CHEMISTRY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats

(2011) JF Lima-Garcia et al.   BRITISH JOURNAL OF PHARMACOLOGY

Baking Reduces Prostaglandin, Resolvin, and Hydroxy-Fatty Acid Content of Farm-Raised Atlantic Salmon (Salmo salar)

(2011) Susan K. Raatz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception

(2010) S Bang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Common structural features of mapeg-a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism

(2010) Per-Johan Jakobsson et al.   PROTEIN SCIENCE