Mice with gene alterations in the GH and IGF family

Sleep deprivation and diet affect human GH gene expression in transgenic mice in vivo

(2020) Jessica S Jarmasz et al.   Endocrine Connections

Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons

(2019) Isadora C. Furigo et al.   Nature Communications

Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice

(2019) Fei Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolactin — a pleiotropic factor in health and disease

(2019) Valérie Bernard et al.   Nature Reviews Endocrinology

Characterization of an intestine-specific GH receptor knockout (IntGHRKO) mouse

(2019) Jonathan A. Young et al.   GROWTH HORMONE & IGF RESEARCH

Insulin Resistance in Patients With Acromegaly

(2019) Greisa Vila et al.   Frontiers in Endocrinology

IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma

(2019) Yunmian Liu et al.   PLoS One

Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver

(2019) María L Bacigalupo et al.   Endocrine Connections

VCAM-1 upregulation accompanies muscle remodeling following resistance-type exercise in Snell dwarf (Pit1dw/dw ) mice

(2018) Erik P. Rader et al.   AGING CELL

MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?

(2018) Reetobrata Basu et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells

(2018) Yasmine Neirijnck et al.   FASEB JOURNAL

Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue

(2018) Rikke Hjortebjerg et al.   GROWTH HORMONE & IGF RESEARCH

Insulin-like growth factors: actions on the skeleton

(2018) Shoshana Yakar et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Growth hormone — past, present and future

(2018) Michael B. Ranke et al.   Nature Reviews Endocrinology

The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects

(2018) Farhad Dehkhoda et al.   Frontiers in Endocrinology

IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots

(2017) David E Maridas et al.   ENDOCRINOLOGY

Insulin, IGF-1, and GH Receptors Are Altered in an Adipose Tissue Depot–Specific Manner in Male Mice With Modified GH Action

(2017) Rikke Hjortebjerg et al.   ENDOCRINOLOGY

IGF1R Expression in Ovarian Granulosa Cells Is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice

(2017) Sarah C. Baumgarten et al.   ENDOCRINOLOGY

IGFBP-4 regulates adult skeletal growth in a sex-specific manner

(2017) David E Maridas et al.   JOURNAL OF ENDOCRINOLOGY

IGF-binding proteins

(2017) L A Bach   JOURNAL OF MOLECULAR ENDOCRINOLOGY

IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling

(2017) Yong Antican Wang et al.   MOLECULAR CANCER RESEARCH

IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge

(2017) Olga Spadaro et al.   Cell Reports

Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

(2017) Gillian Cady et al.   Molecular Metabolism

Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations

(2017) Justin Darcy et al.   Adipocyte

PAPP-A: a promising therapeutic target for healthy longevity

(2016) Cheryl A. Conover et al.   AGING CELL

Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure

(2016) Cristal M. Hill et al.   AGING CELL

Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes

(2016) María Eugenia Matzkin et al.   Aging-US

Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period

(2016) Carolina S. Martinez et al.   CELL CYCLE

Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient MiceCLINICAL PERSPECTIVE

(2016) Yusuke Higashi et al.   CIRCULATION

Growth Hormone Control of Hepatic Lipid Metabolism

(2016) Zhongbo Liu et al.   DIABETES

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

(2016) Jeremie Boucher et al.   DIABETES

Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice

(2016) Adam Jara et al.   ENDOCRINOLOGY

Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

(2016) Justin Darcy et al.   ENDOCRINOLOGY

Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

(2016) Riia K. Junnila et al.   ENDOCRINOLOGY

Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice

(2016) Cheryl A. Conover et al.   EXPERIMENTAL GERONTOLOGY

DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH

(2016) Zhongbo Liu et al.   FASEB JOURNAL

Evidence for a Circadian Effect on the Reduction of Human Growth Hormone Gene Expression in Response to Excess Caloric Intake

(2016) Hana Vakili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

(2016) Brian T. O’Neill et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted Inhibition of Pregnancy-Associated Plasma Protein-A Activity Reduces Atherosclerotic Plaque Burden in Mice

(2016) Cheryl A. Conover et al.   Journal of Cardiovascular Translational Research

Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma

(2016) Xiangjun Kong et al.   Oncotarget

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

(2016) Olga Spadaro et al.   Cell Reports

Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland

(2016) Yang Liu et al.   Journal of Ophthalmology

Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice

(2015) Marianna Sadagurski et al.   AGING CELL

Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver

(2015) Ilona Zawada et al.   Aging-US

Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR−/− mice

(2015) Edward O. List et al.   Aging-US

Protective Role of Insulin-Like Growth Factor-1 Receptor in Endothelial Cells against Unilateral Ureteral Obstruction–Induced Renal Fibrosis

(2015) Ming Liang et al.   AMERICAN JOURNAL OF PATHOLOGY

Transgenic expression of the human growth hormone minigene promotes pancreatic β-cell proliferation

(2015) Mieke Baan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

JAK2 activation by growth hormone and other cytokines

(2015) Michael J. Waters et al.   BIOCHEMICAL JOURNAL

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

(2015) Jose Cordoba-Chacon et al.   DIABETES

The Forgotten Lactogenic Activity of Growth Hormone: Important Implications for Rodent Studies

(2015) Andrzej Bartke et al.   ENDOCRINOLOGY

Regulation of mTOR Activity in Snell Dwarf and GH Receptor Gene-Disrupted Mice

(2015) Graham Dominick et al.   ENDOCRINOLOGY

Glucose Intolerance in Aging Male IGFBP-3 Transgenic Mice: Differential Effects of Human IGFBP-3 and Its Mutant IGFBP-3 Devoid of IGF Binding Ability

(2015) K. Hoa Nguyen et al.   ENDOCRINOLOGY

Growth Hormone Receptor Antagonist Transgenic Mice Are Protected From Hyperinsulinemia and Glucose Intolerance Despite Obesity When Placed on a HF Diet

(2015) Tianxu Yang et al.   ENDOCRINOLOGY

Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular Senescence

(2015) Ross Comisford et al.   GERONTOLOGY

Increased locomotor and thermogenic activity in mice with targeted ablation of the GHRH gene

(2015) Sheila Leone et al.   GROWTH HORMONE & IGF RESEARCH

Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing

(2015) Tao Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis

(2015) Brian T. O’Neill et al.   Cell Reports

The role of PAPP-A in the IGF system: location, location, location

(2015) Claus Oxvig   Journal of Cell Communication and Signaling

Growth hormone receptor signaling is dispensable for HSC function and aging

(2014) M. H. Stewart et al.   BLOOD

Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression

(2014) Bas Brouwers et al.   Cell Metabolism

Liver-Specific GH Receptor Gene-Disrupted (LiGHRKO) Mice Have Decreased Endocrine IGF-I, Increased Local IGF-I, and Altered Body Size, Body Composition, and Adipokine Profiles

(2014) Edward O. List et al.   ENDOCRINOLOGY

Differential Effects of Delayed Aging on Phenotype and Striatal Pathology in a Murine Model of Huntington Disease

(2014) S. J. Tallaksen-Greene et al.   JOURNAL OF NEUROSCIENCE

Expression of Apoptosis-Related Genes in Liver-Specific Growth Hormone Receptor Gene-Disrupted Mice Is Sex Dependent

(2014) A. Gesing et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Prolactin Induces Apoptosis of Lactotropes in Female Rodents

(2014) Jimena Ferraris et al.   PLoS One

Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor

(2014) A. J. Brooks et al.   SCIENCE

Characterization of Cre Recombinase Activity for In Vivo Targeting of Adipocyte Precursor Cells

(2014) Katherine C. Krueger et al.   Stem Cell Reports

Evolution of Hepatic Steatosis to Fibrosis and Adenoma Formation in Liver-Specific Growth Hormone Receptor Knockout Mice

(2014) Yong Fan et al.   Frontiers in Endocrinology

The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty

(2013) Oge Arum et al.   AGE

Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes

(2013) Xinna Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone

(2013) Johanna G. Miquet et al.   CELL CYCLE

Suppression of cytokine signaling: The SOCS perspective

(2013) Edmond M. Linossi et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

(2013) K. Y. Lee et al.   DIABETES

Deletion of Growth Hormone Receptors in Postnatal Skeletal Muscle of Male Mice Does Not Alter Muscle Mass and Response to Pathological Injury

(2013) Archana Vijayakumar et al.   ENDOCRINOLOGY

Effects of isolated GH deficiency on adipose tissue, feeding and adipokines in mice

(2013) Lucia Recinella et al.   GROWTH HORMONE & IGF RESEARCH

Targeted Deletion of Growth Hormone (GH) Receptor in Macrophage Reveals Novel Osteopontin-mediated Effects of GH on Glucose Homeostasis and Insulin Sensitivity in Diet-induced Obesity

(2013) Chunxia Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum IGF-1 Is Insufficient to Restore Skeletal Size in the Total Absence of the Growth Hormone Receptor

(2013) Yingjie Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Role of GH in Adipose Tissue: Lessons from Adipose-Specific GH Receptor Gene-Disrupted Mice

(2013) Edward O. List et al.   MOLECULAR ENDOCRINOLOGY

Disruption of JAK2 in Adipocytes Impairs Lipolysis and Improves Fatty Liver in Mice With Elevated GH

(2013) Sarah M. Nordstrom et al.   MOLECULAR ENDOCRINOLOGY

The GH/IGF-1 axis in ageing and longevity

(2013) Riia K. Junnila et al.   Nature Reviews Endocrinology

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

(2013) Nadia J Kershaw et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice

(2013) Liou Y Sun et al.   eLife

Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading

(2012) Takuo Kubota et al.   ACTA ASTRONAUTICA

IGF-IR signaling attenuates the age-related decline of diastolic cardiac function

(2012) Sarah Moellendorf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice

(2012) Matilda H.-C. Sheng et al.   BONE

Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity

(2012) Marta Derecka et al.   Cell Metabolism

Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice

(2012) H. Imrie et al.   DIABETES

Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity?

(2012) Ellen R Lubbers et al.   JOURNAL OF ENDOCRINOLOGY

GH and IGF1: Roles in Energy Metabolism of Long-Living GH Mutant Mice

(2012) H. M. Brown-Borg et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Insulin-Like Growth Factors and Insulin: At the Crossroad Between Tumor Development and Longevity

(2012) R. Novosyadlyy et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

(2012) Archana Vijayakumar et al.   PLoS One

Metabolic characteristics of long-lived mice

(2012) Andrzej Bartke et al.   Frontiers in Genetics

Prolactin receptor antagonism in mouse anterior pituitary: effects on cell turnover and prolactin receptor expression

(2011) Jimena Ferraris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Generation of Mice Expressing Only the Long Form of the Prolactin Receptor Reveals That Both Isoforms of the Receptor Are Required for Normal Ovarian Function1

(2011) Jamie A. Le et al.   BIOLOGY OF REPRODUCTION

A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

(2011) Robert K Dearth et al.   BMC CANCER

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

(2011) P. Agarwal et al.   DEVELOPMENT

Targeted Loss of GHR Signaling in Mouse Skeletal Muscle Protects Against High-Fat Diet-Induced Metabolic Deterioration

(2011) A. Vijayakumar et al.   DIABETES

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium

(2011) A. Abbas et al.   DIABETES

Endocrine Parameters and Phenotypes of the Growth Hormone Receptor Gene Disrupted (GHR−/−) Mouse

(2011) Edward O. List et al.   ENDOCRINE REVIEWS

Elevated GH/IGF-I, Due to Somatotrope-Specific Loss of Both IGF-I and Insulin Receptors, Alters Glucose Homeostasis and Insulin Sensitivity in a Diet-Dependent Manner

(2011) Manuel D. Gahete et al.   ENDOCRINOLOGY

Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice

(2011) Yingjie Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2

(2011) Brandon C. Sos et al.   JOURNAL OF CLINICAL INVESTIGATION

Global Igfbp1 deletion does not affect prostate cancer development in a c-Myc transgenic mouse model

(2011) Ashley Gray et al.   JOURNAL OF ENDOCRINOLOGY

Transgenic mice expressing the human growth hormone gene provide a model system to study human growth hormone synthesis and secretion in non-tumor-derived pituitary cells: Differential effects of dexamethasone and thyroid hormone

(2011) Hana Vakili et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TSH Compensates Thyroid-Specific IGF-I Receptor Knockout and Causes Papillary Thyroid Hyperplasia

(2011) Kathrin Müller et al.   MOLECULAR ENDOCRINOLOGY

Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes

(2011) Raul M. Luque et al.   PLoS One

Liver-Derived IGF-I Regulates Mean Life Span in Mice

(2011) Johan Svensson et al.   PLoS One

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

Plasma proteomic profiles of bovine growth hormone transgenic mice as they age

(2011) Juan Ding et al.   TRANSGENIC RESEARCH

Lack of Functional Pregnancy-Associated Plasma Protein-A (PAPPA) Compromises Mouse Ovarian Steroidogenesis and Female Fertility1

(2010) Mette Nyegaard et al.   BIOLOGY OF REPRODUCTION

Evidence of a Role for Insulin-Like Growth Factor Binding Protein (IGFBP)-3 in Metabolic Regulation

(2010) P. M. Yamada et al.   ENDOCRINOLOGY

A Novel Effect of Growth Hormone on Macrophage Modulates Macrophage-Dependent Adipocyte Differentiation

(2010) Chunxia Lu et al.   ENDOCRINOLOGY

Ectopic recombination in the central and peripheral nervous system byaP2/FABP4-Cremice: Implications for metabolism research

(2010) Katrin Martens et al.   FEBS LETTERS

Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1

(2010) Sebastien Elis et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sex-specific regulation of body size and bone slenderness by the acid labile subunit

(2010) Hayden-William Courtland et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

(2010) Mahendra D. Mavalli et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted Deletion of Somatotroph Insulin-Like Growth Factor-I Signaling in a Cell-Specific Knockout Mouse Model

(2010) Christopher J. Romero et al.   MOLECULAR ENDOCRINOLOGY

Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors

(2010) V. Rouet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human prostate cancer xenografts in lit/lit mice exhibit reduced growth and androgen-independent progression

(2010) Kiyoshi Takahara et al.   PROSTATE

Use of the Metallothionein Promoter-Human Growth Hormone-Releasing Hormone (GHRH) Mouse to Identify Regulatory Pathways that Suppress Pituitary Somatotrope Hyperplasia and Adenoma Formation due to GHRH-Receptor Hyperactivation

(2009) Raul M. Luque et al.   ENDOCRINOLOGY

Elevated Levels of Insulin-Like Growth Factor (IGF)-I in Serum Rescue the Severe Growth Retardation of IGF-I Null Mice

(2009) YingJie Wu et al.   ENDOCRINOLOGY

Daily energy balance in growth hormone receptor/binding protein (GHR −/−) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency

(2009) Kenneth A. Longo et al.   GROWTH HORMONE & IGF RESEARCH

Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism

(2009) Yong Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alterations in Oxygen Consumption, Respiratory Quotient, and Heat Production in Long-Lived GHRKO and Ames Dwarf Mice, and Short-Lived bGH Transgenic Mice

(2009) Reyhan Westbrook et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice

(2009) Y. Ikeno et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Two-Year Body Composition Analyses of Long-Lived GHR Null Mice

(2009) D. E. Berryman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Long-Lived Ames Dwarf Mice Are Resistant to Chemical Stressors

(2009) Alex F. Bokov et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth

(2009) Catherine E. Gleason et al.   MOLECULAR ENDOCRINOLOGY

Differential Placental Hormone Gene Expression during Pregnancy in a Transgenic Mouse Containing the Human Growth Hormone/Chorionic Somatomammotropin Locus

(2009) Y. Jin et al.   PLACENTA

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth

(2008) N. Kloting et al.   DIABETES

Age-Related Changes in Body Composition of Bovine Growth Hormone Transgenic Mice

(2008) Amanda J. Palmer et al.   ENDOCRINOLOGY

IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis

(2008) Daniela Diehl et al.   INTERNATIONAL JOURNAL OF CANCER

Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: exploring possible relationship to the longevity phenotype

(2008) Cheryl A Conover et al.   JOURNAL OF ENDOCRINOLOGY

Prolactin and Breast Cancer Etiology: An Epidemiologic Perspective

(2008) Shelley S. Tworoger et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Insulin-Like Growth Factor (IGF) Binding Protein-4 Is Both a Positive and Negative Regulator of IGF Activityin Vivo

(2008) Yun Ning et al.   MOLECULAR ENDOCRINOLOGY

Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy

(2008) Jaetaek Kim et al.   MOLECULAR ENDOCRINOLOGY

Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

(2008) Laurent Kappeler et al.   PLOS BIOLOGY