Inhibition of fucoidan on breast cancer cells and potential enhancement of their sensitivity to chemotherapy by regulating autophagy

Combating pancreatic cancer chemoresistance by triggering multiple cell death pathways

(2021) Patricia Santofimia-Castaño et al.   PANCREATOLOGY

Clinicopathological characteristics and treatment of young women with breast cancer in China: a nationwide multicenter 10-year retrospective study

(2021) Wei Zhang et al.   Gland Surgery

Global incidence and mortality of breast cancer: a trend analysis

(2021) Junjie Huang et al.   Aging-US

Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study

(2021) Libo Yu et al.   BMC CANCER

A macrolide from Streptomyces sp. modulates apoptosis and autophagy through Mcl‐1 downregulation in human breast cancer cells

(2021) Chang‐Fang Chiu et al.   ENVIRONMENTAL TOXICOLOGY

Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

(2021) Ewelina Bik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant and Antisteatotic Activities of a New Fucoidan Extracted from Ferula hermonis Roots Harvested on Lebanese Mountains

(2021) Zeinab El Rashed et al.   MOLECULES

Reversal of Multidrug Resistance by Apolipoprotein A1-Modified Doxorubicin Liposome for Breast Cancer Treatment

(2021) Duopeng An et al.   MOLECULES

Hyperglycemia and Chemoresistance in Breast Cancer: From Cellular Mechanisms to Treatment Response

(2021) Jie Qiu et al.   Frontiers in Oncology

Cytotoxicity of Seaweed Compounds, Alone or Combined to Reference Drugs, against Breast Cell Lines Cultured in 2D and 3D

(2021) Fernanda Malhão et al.   Toxics

Coibamide A kills cancer cells through inhibiting autophagy

(2021) Wenli Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trailblazing perspectives on targeting breast cancer stem cells

(2021) Juntao Li et al.   PHARMACOLOGY & THERAPEUTICS

Fucoidan Induces Apoptosis of HT-29 Cells via the Activation of DR4 and Mitochondrial Pathway

(2020) Xu Bai et al.   Marine Drugs

Chlorogenic Acid Alleviates Aβ25-35-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway

(2020) Lijuan Gao et al.   Drug Design Development and Therapy

Fucoidan functionalization on poly(vinyl alcohol) hydrogels for improved endothelialization and hemocompatibility

(2020) Yuan Yao et al.   BIOMATERIALS

Fucoidan increased the sensitivity to gefitinib in lung cancer cells correlates with reduction of TGFβ-mediated Slug expression

(2020) Wei-Lun Qiu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidan Inhibits NLRP3 Inflammasome Activation by Enhancing p62/SQSTM1-Dependent Selective Autophagy to Alleviate Atherosclerosis

(2020) Yufei Cheng et al.   Oxidative Medicine and Cellular Longevity

The Natural Product Fucoidan Inhibits Proliferation and Induces Apoptosis of Human Ovarian Cancer Cells: Focus on the PI3K/Akt Signaling Pathway

(2020) Shuhan Liu et al.   Cancer Management and Research

Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy

(2020) Jie Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting Autophagy in Breast Cancer

(2020) Stefania Cocco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

St. John’s Wort Suppresses Growth in Triple-Negative Breast Cancer Cell Line MDA-MB-231 by Inducing Prodeath Autophagy and Apoptosis

(2020) Mikyoung You et al.   Nutrients

Environmental chemicals, breast cancer progression and drug resistance

(2020) Meriem Koual et al.   Environmental Health

Lysosome-Mediated Cytotoxic Autophagy Contributes to Tea Polysaccharide-Induced Colon Cancer Cell Death via mTOR-TFEB Signaling

(2020) Yujia Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The regulatory factors and pathological roles of autophagy‐related protein 4 in diverse diseases: Recent research advances

(2020) Fan Xia et al.   MEDICINAL RESEARCH REVIEWS

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells

(2020) Ali Alhoshani et al.   OncoTargets and Therapy

Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling

(2020) Szu‐Yuan Wu et al.   Clinical and Translational Medicine

Undaria pinnatifida fucoidan nanoparticles loaded with quinacrine attenuate growth and metastasis of pancreatic cancer

(2020) Samar M. Etman et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Intra-articular injection of anti-inflammatory peptide-loaded glycol chitosan/fucoidan nanogels to inhibit inflammation and attenuate osteoarthritis progression

(2020) Tao Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

JS-K, a nitric oxide donor, induces autophagy as a complementary mechanism inhibiting ovarian cancer

(2019) Bin Liu et al.   BMC CANCER

In vitro induction of endoplasmic reticulum stress in human cervical adenocarcinoma HeLa cells by fucoidan

(2019) Irvine Niyonizigiye et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Study of antioxidant and antibacterial activities of depolymerized fucoidans extracted from Sargassum tenerrimum

(2019) Omid Ashayerizadeh et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells

(2018) Hsien-Yeh Hsu et al.   CANCER LETTERS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

FAM129A regulates autophagy in thyroid carcinomas in an oncogene-dependent manner

(2018) Bruno Nozima et al.   ENDOCRINE-RELATED CANCER

A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines

(2016) Jianqing Zhang et al.   BMC Complementary and Alternative Medicine

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

(2016) Chuanyong Guo et al.   Drug Design Development and Therapy

Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy

(2015) Qixing Tan et al.   CANCER SCIENCE

Autophagy, Metabolism, and Cancer

(2015) E. White et al.   CLINICAL CANCER RESEARCH

Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential

(2015) Farzaneh Atashrazm et al.   Marine Drugs

Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update

(2015) Naoko Takebe et al.   Nature Reviews Clinical Oncology

Anticancer Effect of Fucoidan in Combination with Tyrosine Kinase Inhibitor Lapatinib

(2014) Byeongsang Oh et al.   Evidence-based Complementary and Alternative Medicine

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells

(2013) Zhongyuan Zhang et al.   Marine Drugs

Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo

(2012) Meilan Xue et al.   PLoS One

Antiproliferative Activity of Fucoidan Was Associated with the Induction of Apoptosis and Autophagy in AGS Human Gastric Cancer Cells

(2011) Hyun Soo Park et al.   JOURNAL OF FOOD SCIENCE

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL