The Natural Product Fucoidan Inhibits Proliferation and Induces Apoptosis of Human Ovarian Cancer Cells: Focus on the PI3K/Akt Signaling Pathway

Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms

(2019) Geert van Weelden et al.   Marine Drugs

Cell cycle, cell division, cell death

(2019) Amy Shaub Maddox et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial ovarian cancer

(2019) Stephanie Lheureux et al.   LANCET

Fucoidan Promotes Apoptosis and Inhibits EMT of Breast Cancer Cells

(2019) Xinjia He et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Epithelial ovarian cancer: Evolution of management in the era of precision medicine

(2019) Stephanie Lheureux et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ARHGAP17 suppresses tumor progression and up-regulates P21 and P27 expression via inhibiting PI3K/AKT signaling pathway in cervical cancer

(2019) Qisang Guo et al.   GENE

The relation between PI3K/AKT signalling pathway and cancer

(2019) Saeed Noorolyai et al.   GENE

Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice

(2019) Zhen‐Zhen Yan et al.   HEPATOLOGY

Emerging role of PI3K/AKT in tumor-related epigenetic regulation

(2019) Qi Yang et al.   SEMINARS IN CANCER BIOLOGY

Central Role of Cell Cycle Regulation in the Antitumoral Action of Ocoxin

(2019) Javier Pérez-Peña et al.   Nutrients

Linking cell cycle to stomatal differentiation

(2019) Soon-Ki Han et al.   CURRENT OPINION IN PLANT BIOLOGY

Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells

(2018) Hsien-Yeh Hsu et al.   CANCER LETTERS

Programmed Cell Death, from a Cancer Perspective: An Overview

(2018) Abhay P. Mishra et al.   Molecular Diagnosis & Therapy

Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin

(2018) Vivek K. Pawar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Evaluation Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus in Combination With Anticancer Drugs in Human Cancer Orthotopic Mouse Models

(2017) Maryam Burney et al.   INTEGRATIVE CANCER THERAPIES

Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells

(2017) Hye Park et al.   Marine Drugs

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

(2016) Giuseppa Pistritto et al.   Aging-US

A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines

(2016) Jianqing Zhang et al.   BMC Complementary and Alternative Medicine

Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway

(2016) Min Ho Han et al.   DRUG DEVELOPMENT RESEARCH

Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment

(2016) Lata Mathew et al.   INTEGRATIVE CANCER THERAPIES

Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression

(2016) Gang-Sik Choo et al.   Marine Drugs

Antitumor activity of fucoidan against diffuse large B cell lymphomain vitroandin vivo

(2015) Guang Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Regulation of Bax/mitochondria interaction by AKT

(2015) Lilit Simonyan et al.   FEBS LETTERS

Effects of fucoidan on proliferation, AMP-activated protein kinase, and downstream metabolism- and cell cycle-associated molecules in poorly differentiated human hepatoma HLF cells

(2015) TAKUMI KAWAGUCHI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways

(2015) YONG-SEOK HAN et al.   Molecular Medicine Reports

Fucoidan induces G1 phase arrest and apoptosis through caspases-dependent pathway and ROS induction in human breast cancer MCF-7 cells

(2013) Amal M. Banafa et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

The Anticancer Effect of Fucoidan in PC-3 Prostate Cancer Cells

(2013) Hye-Jin Boo et al.   Marine Drugs

Phenylbutyric acid induces the cellular senescence through an Akt/p21WAF1 signaling pathway

(2012) Hag Dong Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human Lung Cancer Cell via PI3K-Akt-mTOR Pathways

(2012) Hyunkyoung Lee et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Single and 13-Week Oral Toxicity Study of Fucoxanthin Oil from Microalgae in Rats

(2011) Kumiko IIO et al.   Food Hygiene and Safety Science

Bacterial Reverse Mutation Test and Micronucleus Test of Fucoxanthin Oil from Microalgae

(2011) Kumiko IIO et al.   Food Hygiene and Safety Science

Fucoxanthin, a Marine Carotenoid Present in Brown Seaweeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health

(2011) Juan Peng et al.   Marine Drugs

Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation

(2009) Mahdieh Sadidi et al.   BIOCHIMIE

Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice

(2009) Fumiaki Beppu et al.   JOURNAL OF TOXICOLOGICAL SCIENCES