Chlorogenic Acid Alleviates Aβ25-35-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway

TFEB-mediated enhancement of the autophagy-lysosomal pathway dually modulates the process of amyloid β-protein generation in neurons

(2019) Fumiko Yamamoto et al.   NEUROSCIENCE

Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway

(2019) Abubakar Wani et al.   Autophagy

Protective effect of Tenuifolin against Alzheimer’s disease

(2019) Lin Wang et al.   NEUROSCIENCE LETTERS

Effects of daphnetin on the autophagy signaling pathway of fibroblast-like synoviocytes in rats with collagen-induced arthritis (CIA) induced by TNF-α

(2019) Huimin Deng et al.   CYTOKINE

Chlorogenic acid (CGA): A pharmacological review and call for further research

(2018) Muhammad Naveed et al.   BIOMEDICINE & PHARMACOTHERAPY

Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

(2018) Nasimudeen R. Jabir et al.   CNS Neuroscience & Therapeutics

Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease

(2018) Hua Yan et al.   JOURNAL OF BIOSCIENCES

TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities

(2018) Constanza J. Cortes et al.   NEUROBIOLOGY OF DISEASE

Chlorogenic Acid Prevents AMPA-Mediated Excitotoxicity in Optic Nerve Oligodendrocytes Through a PKC and Caspase-Dependent Pathways

(2018) Olfa Rebai et al.   NEUROTOXICITY RESEARCH

Tongluo Xingnao effervescent tablet reverses memory deficit and reduces plaque load in APPswe/PS1dE9 mice

(2018) Wenjun Fu et al.   Experimental and Therapeutic Medicine

Effects of the Aphanizomenon flos-aquae Extract (Klamin®) on a Neurodegeneration Cellular Model

(2018) D. Nuzzo et al.   Oxidative Medicine and Cellular Longevity

A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice

(2018) Domenico Nuzzo et al.   Nutrients

Exploring the Role of Autophagy-Related Gene 5 (ATG5) Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases

(2018) Xin Ye et al.   Frontiers in Immunology

Ouabain activates transcription factor EB and exerts neuroprotection in models of Alzheimer's disease

(2018) Ha-Lim Song et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The mammalian ULK1 complex and autophagy initiation

(2017) Maria Zachari et al.   Essays in Biochemistry

Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy

(2017) Colin M. Huber et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective effect of chlorogenic acid on the inflammatory damage of pancreas and lung in mice with l -arginine-induced pancreatitis

(2017) Tatsuya Ohkawara et al.   LIFE SCIENCES

Associations between hippocampal morphometry and neuropathologic markers of Alzheimer's disease using 7 T MRI

(2017) Anna E. Blanken et al.   NeuroImage-Clinical

Beneficial effects of chlorogenic acid on alcohol-induced damage in PC12 cells

(2016) Shi-Qi Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy

(2016) Secil Erbil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficit of RACK1 contributes to the spatial memory impairment via upregulating BECLIN1 to induce autophagy

(2016) Jiejun Zhu et al.   LIFE SCIENCES

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective

(2016) Heidi Martini-Stoica et al.   TRENDS IN NEUROSCIENCES

MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5

(2015) Catherine L. Nezich et al.   JOURNAL OF CELL BIOLOGY

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

Interactions between gold nanoparticles and amyloid β 25–35 peptide

(2014) Jian Peng et al.   IET Nanobiotechnology

Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury

(2014) Robert Domitrović et al.   TOXICOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagic/lysosomal dysfunction in Alzheimer’s disease

(2013) Miranda E Orr et al.   Alzheimers Research & Therapy

Protective effects of caffeoylquinic acids on the aggregation and neurotoxicity of the 42-residue amyloid β-protein

(2012) Yusaku Miyamae et al.   BIOORGANIC & MEDICINAL CHEMISTRY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Autophagy: A double-edged sword in Alzheimer’s disease

(2012) Ying-Tsen Tung et al.   JOURNAL OF BIOSCIENCES

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chlorogenic Acid and Its Metabolitem-Coumaric Acid Evoke Neurite Outgrowth in Hippocampal Neuronal Cells

(2008) Hideyuki ITO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY