Carotid Body Inflammation: Role in Hypoxia and in the Anti-inflammatory Reflex

Carotid Body Chemoreceptors: Physiology, Pathology, and Implications for Health and Disease

(2021) Rodrigo Iturriaga et al.   PHYSIOLOGICAL REVIEWS

Physiological Sympathetic Activation Reduces Systemic Inflammation: Role of Baroreflex and Chemoreflex

(2021) Fernanda Brognara et al.   Frontiers in Immunology

Asthmatic allergen inhalation sensitises carotid bodies to lysophosphatidic acid

(2021) Nicholas G. Jendzjowsky et al.   Journal of Neuroinflammation

Lactate sensing mechanisms in arterial chemoreceptor cells

(2021) Hortensia Torres-Torrelo et al.   Nature Communications

The impact of damage‐associated molecular patterns on the neurotransmitter release and gene expression in the ex vivo rat carotid body

(2020) Souren Mkrtchian et al.   EXPERIMENTAL PHYSIOLOGY

Growth Factors in the Carotid Body—An Update

(2020) Elena Stocco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Electrostimulation of the carotid sinus nerve in mice attenuates inflammation via glucocorticoid receptor on myeloid immune cells

(2020) Aidan Falvey et al.   Journal of Neuroinflammation

PKCε stimulation of TRPV1 orchestrates carotid body responses to asthmakines

(2020) Nicholas G. Jendzjowsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Logic of Carotid Body Connectivity to the Brain

(2019) Tymoteusz Zera et al.   PHYSIOLOGY

Physiology of the Carotid Body: From Molecules to Disease

(2019) Patricia Ortega-Sáenz et al.   Annual Review of Physiology

All for one - O2 -sensitive K+ channels that mediate carotid body activation

(2018) José López-Barneo   JOURNAL OF PHYSIOLOGY-LONDON

The role of hypoxia-inducible factors in carotid body (patho) physiology

(2018) Gregg L. Semenza et al.   JOURNAL OF PHYSIOLOGY-LONDON

Carotid Bodies and the Integrated Cardiorespiratory Response to Hypoxia

(2018) Bruce G. Lindsey et al.   PHYSIOLOGY

Contribution of Oxidative Stress and Inflammation to the Neurogenic Hypertension Induced by Intermittent Hypoxia

(2018) María P. Oyarce et al.   Frontiers in Physiology

Preventing acute asthmatic symptoms by targeting a neuronal mechanism involving carotid body lysophosphatidic acid receptors

(2018) Nicholas G. Jendzjowsky et al.   Nature Communications

Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by N-Acetylcysteine Supplementation and Arginase Inhibition

(2018) Bernardo J. Krause et al.   Frontiers in Physiology

Gene expression analyses reveal metabolic specifications in acute O2 -sensing chemoreceptor cells

(2017) Lin Gao et al.   JOURNAL OF PHYSIOLOGY-LONDON

Translating carotid body function into clinical medicine

(2017) Rodrigo Iturriaga   JOURNAL OF PHYSIOLOGY-LONDON

The Vagus Nerve in the Neuro-Immune Axis: Implications in the Pathology of the Gastrointestinal Tract

(2017) Bruno Bonaz et al.   Frontiers in Immunology

Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation

(2017) Fernanda Machado Santos-Almeida et al.   Scientific Reports

Insulin resistance: a new consequence of altered carotid body chemoreflex?

(2016) Silvia V. Conde et al.   JOURNAL OF PHYSIOLOGY-LONDON

Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia

(2016) Jayasri Nanduri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

(2016) Esteban A. Moya et al.   Oxidative Medicine and Cellular Longevity

Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling

(2015) M. Carmen Fernández-Agüera et al.   Cell Metabolism

Inflammation and oxidative stress during intermittent hypoxia: the impact on chemoreception

(2015) Rodrigo Iturriaga et al.   EXPERIMENTAL PHYSIOLOGY

Mechanisms of carotid body chemoreflex dysfunction during heart failure

(2015) Harold D. Schultz et al.   EXPERIMENTAL PHYSIOLOGY

Sepsis progression to multiple organ dysfunction in carotid chemo/baro-denervated rats treated with lipopolysaccharide

(2015) Gino Nardocci et al.   JOURNAL OF NEUROIMMUNOLOGY

TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing

(2015) Keith J. Buckler   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Oxygen Sensing and Homeostasis

(2015) Nanduri R. Prabhakar et al.   PHYSIOLOGY

Expressions of angiotensin and cytokine receptors in the paracrine signaling of the carotid body in hypoxia and sleep apnea

(2015) Man Lung Fung   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Oxidative stress in obstructive sleep apnea and intermittent hypoxia – Revisited – The bad ugly and good: Implications to the heart and brain

(2015) Lena Lavie   SLEEP MEDICINE REVIEWS

The human carotid body releases acetylcholine, ATP and cytokines during hypoxia

(2014) Jessica Kåhlin et al.   EXPERIMENTAL PHYSIOLOGY

Synaptic and paracrine mechanisms at carotid body arterial chemoreceptors

(2014) Colin A. Nurse   JOURNAL OF PHYSIOLOGY-LONDON

Pathogenic Roles of the Carotid Body Inflammation in Sleep Apnea

(2014) Man Lung Fung   MEDIATORS OF INFLAMMATION

The cholinergic anti-inflammatory pathway: A critical review

(2013) D. Martelli et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia

(2013) Siu-Yin Lam et al.   EXPERIMENTAL PHYSIOLOGY

Sustained Exposure to Cytokines and Hypoxia Enhances Excitability of Oxygen-Sensitive Type I Cells in Rat Carotid Body: Correlation with the Expression of HIF-1α Protein and Adrenomedullin

(2013) Xuemei Liu et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Inflammatory and immunomodulatory mechanisms in the carotid body

(2013) Andrea Porzionato et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Pro-inflammatory cytokines do not affect basal or hypoxia-stimulated discharge of rat vagal paraganglia

(2012) Edward T. O'Connor et al.   EXPERIMENTAL PHYSIOLOGY

Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat

(2012) Ana P. Abdala et al.   JOURNAL OF PHYSIOLOGY-LONDON

The vagus nerve and the inflammatory reflex—linking immunity and metabolism

(2012) Valentin A. Pavlov et al.   Nature Reviews Endocrinology

NO modulation of carotid body chemoreception in health and disease

(2012) Esteban A. Moya et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Inflammation in the carotid body during development and its contribution to apnea of prematurity

(2012) Estelle B. Gauda et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia

(2011) Rodrigo Del Rio et al.   BRAIN RESEARCH

Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia

(2011) Rodrigo Del Rio et al.   EUROPEAN RESPIRATORY JOURNAL

Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways

(2011) Siu-Yin Lam et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Immunosensory signalling by carotid body chemoreceptors

(2011) Patricio Zapata et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Ibuprofen blocks time-dependent increases in hypoxic ventilation in rats

(2011) Dan Popa et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Pathophysiology of Sleep Apnea

(2010) Jerome A. Dempsey et al.   PHYSIOLOGICAL REVIEWS

The effect of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat

(2010) Brian Mac Grory et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Lipopolysaccharide signaling in the carotid chemoreceptor pathway of rats with sepsis syndrome

(2010) Ricardo Fernández et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Carotid body potentiation induced by intermittent hypoxia: Implications for cardiorespiratory changes induced by sleep apnoea

(2009) Rodrigo Iturriaga et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link

(2009) R. Del Rio et al.   EUROPEAN RESPIRATORY JOURNAL

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

(2009) J. F. Garvey et al.   EUROPEAN RESPIRATORY JOURNAL

NADPH Oxidase Is Required for the Sensory Plasticity of the Carotid Body by Chronic Intermittent Hypoxia

(2009) Y.- J. Peng et al.   JOURNAL OF NEUROSCIENCE

Interleukin-6 increases intracellular Ca2+concentration and induces catecholamine secretion in rat carotid body glomus cells

(2009) Juan Fan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body

(2008) X. Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia

(2008) Anita Pawar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sleep Apnea and Cardiovascular Disease

(2008) Virend K. Somers et al.   CIRCULATION

Lipopolysaccharide-induced carotid body inflammation in cats: functional manifestations, histopathology and involvement of tumour necrosis factor-α

(2008) Ricardo Fernández et al.   EXPERIMENTAL PHYSIOLOGY

Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body

(2008) Siu-Yin Lam et al.   HISTOCHEMISTRY AND CELL BIOLOGY