Gene expression analyses reveal metabolic specifications in acute O2 -sensing chemoreceptor cells

Redox signaling in acute oxygen sensing

(2017) Lin Gao et al.   Redox Biology

Carotid Body Ablation Abrogates Hypertension and Autonomic Alterations Induced by Intermittent Hypoxia in RatsNovelty and Significance

(2016) Rodrigo Del Rio et al.   HYPERTENSION

CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia

(2016) Vladislav V. Makarenko et al.   JOURNAL OF NEUROPHYSIOLOGY

Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion

(2016) Patricia Ortega-Sáenz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Single cell transcriptome analysis of mouse carotid body glomus cells

(2016) Ting Zhou et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxygen-sensing by arterial chemoreceptors: Mechanisms and medical translation

(2016) José López-Barneo et al.   MOLECULAR ASPECTS OF MEDICINE

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

(2016) Natalie J. German et al.   MOLECULAR CELL

Evaluation of markers of beige adipocytes in white adipose tissue of the mouse

(2016) Rolando A. Garcia et al.   Nutrition & Metabolism

Defining an olfactory receptor function in airway smooth muscle cells

(2016) William H. Aisenberg et al.   Scientific Reports

Acute Oxygen Sensing—Inching Ever Closer to an Elusive Mechanism

(2015) Chris Peers   Cell Metabolism

Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling

(2015) M. Carmen Fernández-Agüera et al.   Cell Metabolism

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway

(2015) Emma J. Hodson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   JOURNAL OF PHYSIOLOGY-LONDON

The subunit composition and function of mammalian cytochrome c oxidase

(2015) Bernhard Kadenbach et al.   MITOCHONDRION

Oxygen regulation of breathing through an olfactory receptor activated by lactate

(2015) Andy J. Chang et al.   NATURE

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer

(2015) M van Geldermalsen et al.   ONCOGENE

Cav1.3 Channels as Key Regulators of Neuron-Like Firings and Catecholamine Release in Chromaffin Cells

(2015) David Vandael et al.   Current Molecular Pharmacology

Chronic opioids regulate KATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase A

(2014) Shaima Salman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An O2-Sensitive Glomus Cell-Stem Cell Synapse Induces Carotid Body Growth in Chronic Hypoxia

(2014) Aida Platero-Luengo et al.   CELL

Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia

(2014) D. Macias et al.   EMBO Molecular Medicine

Increase in cytosolic Ca2+produced by hypoxia and other depolarizing stimuli activates a non-selective cation channel in chemoreceptor cells of rat carotid body

(2014) Dawon Kang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

(2014) Chendong Yang et al.   MOLECULAR CELL

Uncoupling Protein 2 Deficiency Mimics the Effects of Hypoxia and Endoplasmic Reticulum Stress on Mitochondria and Triggers Pseudohypoxic Pulmonary Vascular Remodeling and Pulmonary Hypertension

(2013) Peter Dromparis et al.   CIRCULATION RESEARCH

Carotid Body Denervation Prevents the Development of Insulin Resistance and Hypertension Induced by Hypercaloric Diets

(2013) Maria J. Ribeiro et al.   DIABETES

Oxygen sensitivity of mitochondrial function in rat arterial chemoreceptor cells

(2013) Keith J. Buckler et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cellular properties and chemosensory responses of the human carotid body

(2013) Patricia Ortega-Sáenz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells

(2013) Philip J. Turner et al.   JOURNAL OF PHYSIOLOGY-LONDON

Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure

(2013) Noah J. Marcus et al.   JOURNAL OF PHYSIOLOGY-LONDON

Crystal structure of the entire respiratory complex I

(2013) Rozbeh Baradaran et al.   NATURE

Lidocaine effects on acetylcholine-elicited currents from mouse superior cervical ganglion neurons

(2013) Armando Alberola-Die et al.   NEUROSCIENCE RESEARCH

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

(2013) Siddhesh Aras et al.   NUCLEIC ACIDS RESEARCH

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension

(2013) Fiona D. McBryde et al.   Nature Communications

Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries

(2012) Renate Paddenberg et al.   CARDIOVASCULAR RESEARCH

NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain

(2012) Eduardo Balsa et al.   Cell Metabolism

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

(2012) Maik Hüttemann et al.   FASEB JOURNAL

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

The human carotid body transcriptome with focus on oxygen sensing and inflammation - a comparative analysis

(2012) Souren Mkrtchian et al.   JOURNAL OF PHYSIOLOGY-LONDON

Differential Impairment of Catecholaminergic Cell Maturation and Survival by Genetic Mitochondrial Complex II Dysfunction

(2012) B. Diaz-Castro et al.   MOLECULAR AND CELLULAR BIOLOGY

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

(2011) Daniel Tello et al.   Cell Metabolism

Hypoxia-inducible factor 2  (HIF-2 ) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

(2011) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Carotid Body

(2010) Malin Jonsson Fagerlund et al.   ANESTHESIOLOGY

Carotid body chemosensory responses in mice deficient of TASK channels

(2010) Patricia Ortega-Sáenz et al.   JOURNAL OF GENERAL PHYSIOLOGY

HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression

(2010) Daniel A. Tennant et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Divergent roles of reactive oxygen species in the responses of perinatal adrenal chromaffin cells to hypoxic challenges

(2010) Stephen T. Brown et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Regulation of Oxygen Sensitivity in Adrenal Chromaffin Cells

(2009) Colin A. Nurse et al.   Annals of the New York Academy of Sciences

Neural KCNQ (Kv7) channels

(2009) David A Brown et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chronic Nicotine Blunts Hypoxic Sensitivity in Perinatal Rat Adrenal Chromaffin Cells via Upregulation of KATP Channels: Role of  7 Nicotinic Acetylcholine Receptor and Hypoxia-Inducible Factor-2 

(2009) J. Buttigieg et al.   JOURNAL OF NEUROSCIENCE

Heteromeric TASK-1/TASK-3 is the major oxygen-sensitive background K+channel in rat carotid body glomus cells

(2009) Donghee Kim et al.   JOURNAL OF PHYSIOLOGY-LONDON

Developmental change of T-type Ca2+channel expression and its role in rat chromaffin cell responsiveness to acute hypoxia

(2009) Konstantin L. Levitsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

Functional mitochondria are required for O2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells

(2008) J. Buttigieg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modulation of TRPC5 cation channels by halothane, chloroform and propofol

(2008) Y M Bahnasi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3-/- Mice

(2008) T. Bishop et al.   MOLECULAR AND CELLULAR BIOLOGY

Absolute requirement of GDNF for adult catecholaminergic neuron survival

(2008) Alberto Pascual et al.   NATURE NEUROSCIENCE