The role of hypoxia-inducible factors in carotid body (patho) physiology

Association of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea

(2017) Jie Yu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Complementary roles of gasotransmitters CO and H2S in sleep apnea

(2017) Ying-Jie Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting renal cell carcinoma with a HIF-2 antagonist

(2016) Wenfang Chen et al.   NATURE

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

(2016) Hyejin Cho et al.   NATURE

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

Protein kinase G–regulated production of H2S governs oxygen sensing

(2015) Guoxiang Yuan et al.   Science Signaling

Protein kinase G–regulated production of H2S governs oxygen sensing

(2015) Guoxiang Yuan et al.   Science Signaling

Regulation of hypoxia-inducible factor-α isoforms and redox state by carotid body neural activity in rats

(2014) Ying-Jie Peng et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sleep-Disordered Breathing and Resistant Hypertension

(2014) Angela Yee-Moon Wang   SEMINARS IN NEPHROLOGY

Increased Prevalence of Sleep-Disordered Breathing in Adults

(2013) P. E. Peppard et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Hypoxia-Inducible Factor 1 and Cardiovascular Disease

(2013) Gregg L. Semenza   Annual Review of Physiology

Mutual antagonism between hypoxia-inducible factors 1  and 2  regulates oxygen sensing and cardio-respiratory homeostasis

(2013) G. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2

(2012) Nanduri R. Prabhakar et al.   PHYSIOLOGICAL REVIEWS

Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression

(2012) W. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia

(2011) Guoxiang Yuan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypoxia-inducible factor 2  (HIF-2 ) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

(2011) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology of Sleep Apnea

(2010) Jerome A. Dempsey et al.   PHYSIOLOGICAL REVIEWS

H2S mediates O2 sensing in the carotid body

(2010) Y.-J. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH Oxidase Is Required for the Sensory Plasticity of the Carotid Body by Chronic Intermittent Hypoxia

(2009) Y.- J. Peng et al.   JOURNAL OF NEUROSCIENCE

Intermittent hypoxia degrades HIF-2  via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities

(2009) J. Nanduri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of HIF-1α expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca2+signaling, prolyl hydroxylases, and mTOR

(2008) Guoxiang Yuan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL