Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by N-Acetylcysteine Supplementation and Arginase Inhibition

Divergent roles of endothelial nitric oxide synthases system in maintaining cardiovascular homeostasis

(2017) Shigeo Godo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Responses to reductive stress in the cardiovascular system

(2017) Diane E. Handy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Blood pressure control in hypertension. Pros and cons of available treatment strategies

(2017) Giuseppe Mancia et al.   JOURNAL OF HYPERTENSION

Fetal Growth Restriction Induces Heterogeneous Effects on Vascular Biomechanical and Functional Properties in Guinea Pigs (Cavia porcellus)

(2017) Daniel Cañas et al.   Frontiers in Physiology

Carotid Body Ablation Abrogates Hypertension and Autonomic Alterations Induced by Intermittent Hypoxia in RatsNovelty and Significance

(2016) Rodrigo Del Rio et al.   HYPERTENSION

Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation

(2016) Esteban A. Moya et al.   Oxidative Medicine and Cellular Longevity

HIF2α–arginase axis is essential for the development of pulmonary hypertension

(2016) Andrew S. Cowburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development

(2015) Mohamed Montassar Lasram et al.   CLINICAL BIOCHEMISTRY

Arginase–endothelial nitric oxide synthase imbalance contributes to endothelial dysfunction during chronic intermittent hypoxia

(2015) Bernardo J. Krause et al.   JOURNAL OF HYPERTENSION

Arginase: an old enzyme with new tricks

(2015) Ruth B. Caldwell et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study.

(2015) Bernard Schmitt et al.   Redox Biology

Hypobaric hypoxia induced arginase expression limits nitric oxide availability and signaling in rodent heart

(2014) Manjulata Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Arginase activity and nitric oxide levels in patients with obstructive sleep apnea syndrome

(2014) M Yuksel et al.   Clinics

Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia

(2014) Rodrigo Iturriaga et al.   Frontiers in Physiology

Efficient nitrosation of glutathione by nitric oxide

(2013) Bernd Kolesnik et al.   FREE RADICAL BIOLOGY AND MEDICINE

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

(2013) Gordon F. Rushworth et al.   PHARMACOLOGY & THERAPEUTICS

Sympatho-adrenal activation by chronic intermittent hypoxia

(2012) Nanduri R. Prabhakar et al.   JOURNAL OF APPLIED PHYSIOLOGY

Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins

(2012) B.J. Krause et al.   PLACENTA

Endothelial eNOS/arginase imbalance contributes to vascular dysfunction in IUGR umbilical and placental vessels

(2012) B.J. Krause et al.   PLACENTA

Xanthine Oxidase Inhibition Attenuates Endothelial Dysfunction Caused by Chronic Intermittent Hypoxia in Rats

(2011) John M. Dopp et al.   RESPIRATION

Hypoxic upregulation of arginase II in human lung endothelial cells

(2010) Karina Krotova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endothelial Dysfunction in the Microcirculation of Patients with Obstructive Sleep Apnea

(2010) Brian T. Patt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension

(2010) Teddy Bagnost et al.   CARDIOVASCULAR RESEARCH

Pathophysiology of Sleep Apnea

(2010) Jerome A. Dempsey et al.   PHYSIOLOGICAL REVIEWS

Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia

(2010) Nanduri R. Prabhakar et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Hypoxia promotes human pulmonary artery smooth muscle cell proliferation through induction of arginase

(2009) Bernadette Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Carotid body potentiation induced by intermittent hypoxia: Implications for cardiorespiratory changes induced by sleep apnoea

(2009) Rodrigo Iturriaga et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link

(2009) R. Del Rio et al.   EUROPEAN RESPIRATORY JOURNAL

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

(2009) J. F. Garvey et al.   EUROPEAN RESPIRATORY JOURNAL

Reaction between nitric oxide, glutathione, and oxygen in the presence and absence of protein: How are S-nitrosothiols formed?

(2009) Agnes Keszler et al.   FREE RADICAL BIOLOGY AND MEDICINE

Treatment with the arginase inhibitor Nω-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat

(2009) Teddy Bagnost et al.   JOURNAL OF HYPERTENSION

Time course of intermittent hypoxia-induced impairments in resistance artery structure and function

(2009) Nathan R. Philippi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

The multiple challenges of obstructive sleep apnea in children: diagnosis

(2008) Leila Kheirandish-Gozal et al.   CURRENT OPINION IN PEDIATRICS

Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives

(2008) P. Levy et al.   EUROPEAN RESPIRATORY JOURNAL