Copper-Catalyzed (4+1) Cascade Annulation of Terminal Alkynes with 2-(Tosylmethyl)anilines: Synthesis of 2,3-Disubstituted Indoles

Palladium-Catalyzed Asymmetric (4 + 2) Annulation of γ-Methylidene-δ-valerolactones with Alkenes: Enantioselective Synthesis of Functionalized Chiral Cyclohexyl Spirooxindoles

(2021) Zhi-Long Jia et al.   ORGANIC LETTERS

Tandem (2 + 2) Annulation/Retro-4π Electrocyclization/Imino-Nazarov Cyclization Reaction of p-Quinone Methides with Ynamides: Expeditious Construction of Functionalized Aminoindenes

(2021) Ke-Yin Yu et al.   ORGANIC LETTERS

Tandem Phospha‐Michael Addition/ N ‐Acylation/ Intramolecular Wittig Reaction of aza‐ o ‐Quinone Methides: Approaches to 2,3‐Disubstituted Indoles

(2020) Ting‐Bi Hua et al.   ADVANCED SYNTHESIS & CATALYSIS

One-Pot Tandem ortho-Naphthoquinone-Catalyzed Aerobic Nitrosation of N-Alkylanilines and Rh(III)-Catalyzed C–H Functionalization Sequence to Indole and Aniline Derivatives

(2020) Tengda Si et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Unprotected and Highly Substituted Indoles by the Ruthenium(II)-Catalyzed Reaction of Phenyl Isocyanates with Diaryl/Diheteroaryl Alkynes/Ethyl-3-phenyl Propiolates

(2020) Amrendra Kumar et al.   ORGANIC LETTERS

Formal [4+1] Cycloaddition of o ‐Aminobenzyl Chlorides with Isocyanides: Synthesis of 2‐Amino‐3‐Substituted Indoles

(2019) Jacobus A. W. Jong et al.   HELVETICA CHIMICA ACTA

A Formal Condensation and [4+1] Annulation Reaction of 3‐Isothiocyanato Oxindoles with Aza‐ o ‐Quinone Methides

(2019) Hou‐Ze Gui et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach

(2019) Yu-Chen Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Catalytic [4+5] Annulation of ortho ‐Quinone Methides with Vinylethylene Carbonates and its Extension to Stereoselective Tandem Rearrangement

(2019) Xian‐Tao An et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent advances in the application of Diels–Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis

(2018) Baochao Yang et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Electrochemical Dehydrogenative Alkyne Annulation

(2018) Fan Xu et al.   ACS Catalysis

Stereoselective Reactions of ortho-Quinone Methide and ortho-Quinone Methide Imines and Their Utility in Natural Product Synthesis

(2018) Alan Spivey et al.   SYNTHESIS-STUTTGART

Cinchona Alkaloid Catalyzed Enantioselective [4 + 2] Annulation of Allenic Esters and in Situ Generated ortho-Quinone Methides: Asymmetric Synthesis of Functionalized Chromans

(2017) Yu-Hua Deng et al.   JOURNAL OF ORGANIC CHEMISTRY

Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes

(2016) Hayden A. Sharma et al.   CHEMICAL COMMUNICATIONS

Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis

(2016) Ashley A. Jaworski et al.   JOURNAL OF ORGANIC CHEMISTRY

A Mild and General Larock Indolization Protocol for the Preparation of Unnatural Tryptophans

(2016) Kangway V. Chuang et al.   ORGANIC LETTERS

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

(2015) John G. Luz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mild and Efficient One-Pot Synthesis of 2-(Perfluoroalkyl)indoles by Means of Sequential Michael-Type Addition and Pd(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) Reaction

(2015) Dandan Shen et al.   ORGANIC LETTERS

N-Heterocyclic-Carbene-Catalyzed Synthesis of 2-Aryl Indoles

(2014) M. Todd Hovey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Synthesis of 2-(Perfluoroalkyl)indoles through a Michael Addition/CuI-Catalyzed Annulation Process

(2014) Long Cao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Gold Catalysis Coupled with Visible Light Stimulation: Syntheses of Functionalized Indoles

(2014) Shunyou Cai et al.   ORGANIC LETTERS

Asymmetric Catalytic 1,6-Conjugate Addition/Aromatization ofpara-Quinone Methides: Enantioselective Introduction of Functionalized Diarylmethine Stereogenic Centers

(2013) Wen-Dao Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Optically Active Indolines by Formal [4+1] Annulation of Sulfur Ylides andN-(ortho-Chloromethyl)aryl Amides

(2013) Qing-Qing Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot and Regiospecific Synthesis of 2,3-Disubstituted Indoles from 2-Bromoanilides via Consecutive Palladium-Catalyzed Sonogashira Coupling, Amidopalladation, and Reductive Elimination

(2013) Bruce Z. Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Biomedical Importance of Indoles

(2013) Nagendra Kaushik et al.   MOLECULES

Coupling and Cyclization of o-Iodoanilines and Propargylic Bromides via Allenes: An Efficient Entry to Indomethacin

(2013) Can Zhu et al.   ORGANIC LETTERS

Transition-metal-free approach to synthesis of indolines from N-(ortho-chloromethyl)aryl amides and iodonium ylides

(2013) Hui Huang et al.   TETRAHEDRON LETTERS

Synthesis of Indoles through Highly Efficient Cascade Reactions of Sulfur Ylides and N-(ortho-Chloromethyl)aryl Amides

(2012) Qing-Qing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

(2012) Mélanie Platon et al.   CHEMICAL SOCIETY REVIEWS

Indole Synthesis by Conjugate Addition of Anilines to Activated Acetylenes and an Unusual Ligand-Free Copper(II)-Mediated Intramolecular Cross-Coupling

(2012) Detian Gao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indole synthesis – something old, something new

(2012) Martyn Inman et al.   Chemical Science

Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions

(2011) Sandro Cacchi et al.   CHEMICAL REVIEWS

Efficient and simple zinc-mediated synthesis of 3-amidoindoles

(2011) Anahit Pews-Davtyan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Indole synthesis: a review and proposed classification

(2011) Douglass F. Taber et al.   TETRAHEDRON

Gold-Catalyzed Cycloisomerization Reactions of 2-Tosylaminophenylprop-1-yn-3-ols as a Versatile Approach for Indole Synthesis

(2010) Prasath Kothandaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Dichotomy with Alkynes in the Formal Hydrohydrazination/Fischer Indolization Tandem Reaction Catalyzed by a Ph3PAuNTf2/pTSA Binary System

(2010) Nitin T. Patil et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium on carbon-catalyzed synthesis of 2- and 2,3-substituted indoles under heterogeneous conditions

(2010) Yasunari Monguchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper catalysis in the construction of indole and benzo[b]furan rings

(2010) Sandro Cacchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Indoles from Simple Anilines and Alkynes: Palladium-Catalyzed CH Activation Using Dioxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient, microwave-assisted, one-pot synthesis of indoles under Sonogashira conditions

(2009) Yu Chen et al.   TETRAHEDRON

Catalytic Synthesis of Indoles from Alkynes

(2008) Karolin Krüger (née Alex) et al.   ADVANCED SYNTHESIS & CATALYSIS

Zinc-Promoted Hydrohydrazination of Terminal Alkynes: An Efficient Domino Synthesis of Indoles

(2008) Karolin Alex et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Indole Synthesis via Rhodium Catalyzed Oxidative Coupling of Acetanilides and Internal Alkynes

(2008) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY