Progress in palladium-based catalytic systems for the sustainable synthesis of annulated heterocycles: a focus on indole backbones

Domino Sonogashira Coupling/Cyclization Reaction Catalyzed by Copper and ppb Levels of Palladium: A Concise Route to Indoles and Benzo[b]furans

(2011) Ruiping Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-catalyzed synthesis of indoles via ammonia cross-coupling–alkyne cyclization

(2011) Pamela G. Alsabeh et al.   CHEMICAL COMMUNICATIONS

Direct Arylation of Heteroaromatic Compounds with Congested, Functionalised Aryl Bromides at Low Palladium/Triphosphane Catalyst Loading

(2011) David Roy et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Unsymmetrical 2,2′-Biindolyl Derivatives by a Cu-CatalyzedN-Arylation/Pd-Catalyzed Direct Arylation Sequential Process

(2011) Zhi-Jing Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis ofN-(2-Pyridyl)indoles via Pd(II)-Catalyzed Oxidative Coupling

(2011) Jinlei Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

ortho-Bromo(propa-1,2-dien-1-yl)arenes: Substrates for Domino Reactions

(2011) Kye-Simeon Masters et al.   JOURNAL OF ORGANIC CHEMISTRY

Why Do Some Fischer Indolizations Fail?

(2011) Nihan Çelebi-Ölçüm et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heck reaction of arenediazonium salts with N,N-diprotected allylamines. Synthesis of cinnamylamines and indoles

(2011) Sandro Cacchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent advances in indole syntheses: New routes for a classic target

(2011) Rubén Vicente   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Intramolecular Trapping of the Blaise Reaction Intermediate for Tandem One-Pot Synthesis of Indole Derivatives

(2011) Ju Hyun Kim et al.   ORGANIC LETTERS

Recent advances in the Heck–Matsuda reaction in heterocyclic chemistry

(2011) François-Xavier Felpin et al.   TETRAHEDRON

A convenient Fischer indole synthesis of 2,3′-biindoles

(2011) Philip E. Alford et al.   TETRAHEDRON LETTERS

Synthesis of indoles via palladium-catalyzed C–H activation of N-aryl amides followed by coupling with alkynes

(2011) Feng Zhou et al.   TETRAHEDRON LETTERS

Larock heteroannulation of 2-bromoanilines with internal alkynes via ligand and salt free Pd/C catalysed reaction

(2011) Nelly Batail et al.   TETRAHEDRON LETTERS

Efficient indoles and anilines syntheses employing tert-butyl sulfinamide as ammonia surrogate

(2011) Anjanappa Prakash et al.   TETRAHEDRON LETTERS

Gold-Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl-Annulated[a]carbazoles from Aniline-Substituted Diethynylarenes

(2010) Kimio Hirano et al.   ADVANCED SYNTHESIS & CATALYSIS

A Novel One-Pot, Two-Step Synthesis of Polycyclic Indoles via Tandem Intramolecular Hydroamidation/Palladium-Catalyzed Annulation

(2010) Jianxiu Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Multicomponent Cascade Reactions: A Novel and Expedient Approach to Functionalized Indoles by an Unprecedented Nucleophilic Addition-Heterocyclization-Oxidative Alkoxycarbonylation Sequence

(2010) Bartolo Gabriele et al.   ADVANCED SYNTHESIS & CATALYSIS

Cascade Palladium-Catalyzed Direct Intramolecular Arylation/Alkene Isomerization Sequences: Synthesis of Indoles and Benzofurans

(2010) Myriam Yagoubi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading

(2010) David Roy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Larock indole synthesis using palladium complexes immobilized onto mesoporous silica

(2010) Nelly Batail et al.   APPLIED CATALYSIS A-GENERAL

A general and mild domino approach to substituted 1-aminoindoles

(2010) Nis Halland et al.   CHEMICAL COMMUNICATIONS

Room-Temperature, Ligand- and Base-Free Heck Reactions of Aryl Diazonium Salts at Low Palladium Loading: Sustainable Preparation of Substituted Stilbene Derivatives

(2010) François-Xavier Felpin et al.   CHEMISTRY-A EUROPEAN JOURNAL

A General Synthesis of Alkenyl-Substituted Benzofurans, Indoles, and Isoquinolones by Cascade Palladium-Catalyzed Heterocyclization/Oxidative Heck Coupling

(2010) Rosana Álvarez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and antimicrobial activities of novel 1H-dibenzo[a,c]carbazoles from dehydroabietic acid

(2010) Wen Gu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antiproliferative activity of oxazinocarbazole and N,N-bis(carbazolylmethyl)amine derivatives

(2010) Samar Issa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Domino approach to 2-aroyltrimethoxyindoles as novel heterocyclic combretastatin A4 analogues

(2010) Martin Arthuis et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Synthesis of Pyrimido[1,6-a]indol-1(2H)-one Derivatives by a Nucleophilic Addition/Cu-Catalyzed N-Arylation/Pd-Catalyzed C−H Activation Sequential Process

(2010) Zhi-Jing Wang et al.   ORGANIC LETTERS

A Novel Approach to 3-Methylindoles by a Heck/Cyclization/Isomerization Process

(2010) Carl A. Baxter et al.   ORGANIC LETTERS

2,3-Disubstituted Indoles via Palladium-Catalyzed Reaction of 2-Alkynyltrifluoroacetanilides with Arenediazonium Tetrafluoroborates

(2010) Sandro Cacchi et al.   ORGANIC LETTERS

Exploiting the Chemistry of Strained Rings: Synthesis of Indoles via Domino Reaction of Aryl Iodides with 2H-Azirines

(2010) David A. Candito et al.   ORGANIC LETTERS

Second-Generation Process Research Towards Eletriptan: A Fischer Indole Approach

(2010) Christopher P. Ashcroft et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A study on the synthesis of structural analogs of bis-indole alkaloid caulerpin: a step-by-step synthesis of a cyclic indole-tetramer

(2010) Oktay Talaz et al.   TETRAHEDRON

Palladium catalyzed tandem alkenyl- and aryl-C–N bond formation: a cascade N-annulation route to 4-, 5-, 6- and 7-chloroindoles

(2010) Luke C. Henderson et al.   TETRAHEDRON

Synthesis of 2-substituted indoles via a palladium-catalyzed domino Heck reaction and dealkylation

(2010) Hui Mao et al.   TETRAHEDRON LETTERS

The first intramolecular Heck–Matsuda reaction and its application in the syntheses of benzofurans and indoles

(2010) Fernanda A. Siqueira et al.   TETRAHEDRON LETTERS

First Heterogeneous Ligand- and Salt-Free Larock Indole Synthesis

(2009) Nelly Batail et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Annulation of 2-(1-Alkynyl)benzenamines with Disulfides: Synthesis of 3-Sulfenylindoles

(2009) Yan-Jin Guo et al.   ADVANCED SYNTHESIS & CATALYSIS

One-Step Synthesis of the Benzocyclo[penta- to octa-]isoindole Core

(2009) Yimin Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Indoles from Simple Anilines and Alkynes: Palladium-Catalyzed CH Activation Using Dioxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Conjugated Polymers for Organic Solar Cell Applications

(2009) Yen-Ju Cheng et al.   CHEMICAL REVIEWS

Antifungal Carbazoles

(2009) Karin Thevissen et al.   CURRENT MEDICINAL CHEMISTRY

Efficient Total Synthesis of (−)-cis-Clavicipitic Acid

(2009) Zhengren Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Two-Step Synthesis of Aza- and Diazaindoles from Chloroamino-N-heterocycles Using Ethoxyvinylborolane

(2009) Daniel K. Whelligan et al.   JOURNAL OF ORGANIC CHEMISTRY

Modular Synthesis of Indoles from Imines ando-Dihaloarenes oro-Chlorosulfonates by a Pd-Catalyzed Cascade Process

(2009) José Barluenga et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Domino C,N-Coupling/Carbonylation/Suzuki Coupling Reaction: An Efficient Synthesis of 2-Aroyl-/Heteroaroylindoles

(2009) Martin Arthuis et al.   ORGANIC LETTERS

Wacker-Type Oxidation of Alkynes into 1,2-Diketones Using Molecular Oxygen

(2009) Wei Ren et al.   ORGANIC LETTERS

Palladium-Catalyzed Indolization ofN-Aroylbenzotriazoles with Disubstituted Alkynes

(2009) Itaru Nakamura et al.   ORGANIC LETTERS

An efficient, microwave-assisted, one-pot synthesis of indoles under Sonogashira conditions

(2009) Yu Chen et al.   TETRAHEDRON

Palladium-catalyzed sequential indole synthesis using sterically hindered amines

(2009) Lutz Ackermann et al.   TETRAHEDRON

One-pot N-alkylation/Heck approach to substituted indoles

(2009) Melissa L. Weinrich et al.   TETRAHEDRON LETTERS

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Synthesis of Indoles from Alkynes

(2008) Karolin Krüger (née Alex) et al.   ADVANCED SYNTHESIS & CATALYSIS

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Biologically Active Carbazole Alkaloids Using Selective Transition-metal-catalyzed Coupling Reactions

(2008) Hans-Joachim Knölker   CHEMISTRY LETTERS

Intramolecular Pd(0)-Catalyzed Reactions of β-(2-Iodoanilino) Carboxamides: Enolate Arylation and Nucleophilic Substitution at the Carboxamide Group

(2008) Daniel Solé et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Oxindoles by Tandem Heck-Reduction-Cyclization (HRC) from a Single Bifunctional, in Situ Generated Pd/C Catalyst

(2008) François-Xavier Felpin et al.   JOURNAL OF ORGANIC CHEMISTRY

On the Mechanistic Behavior of Highly Efficient Palladium−Tetraphosphine Catalytic Systems for Cross-Coupling Reactions: First Spectroscopic and Electrochemical Studies of Oxidative Addition on Pd(0)/Multidentate Ferrocenylpolyphosphine Complexes

(2008) D. Evrard et al.   ORGANOMETALLICS

Novel synthesis of fused indoles and 2-substituted indoles by the palladium-catalyzed cyclization of N-cycloalkenyl-o-haloanilines

(2008) Jun Maruyama et al.   TETRAHEDRON

Indole synthesis: palladium-catalyzed C–H bond amination via reduction of nitroalkenes with carbon monoxide

(2008) Tom H.H. Hsieh et al.   TETRAHEDRON

Regioselective Pd-catalyzed indolization of 2-bromoanilines with internal alkynes using phosphine-free ligands

(2008) Xin Cui et al.   TETRAHEDRON LETTERS

Palladium-Catalyzed Aryl Amination–Heck Cyclization Cascade: A One-Flask Approach to 3-Substituted Indoles

(2007) Thomas Jensen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Multicomponent Synthesis of Indoles from 2-Iodobenzoic Acid

(2007) Olivier Leogane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and optical properties of benzocarbazole-substituted polysiloxanes for polymeric photorefractive materials

(2007) In Kyu Moon et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Annulation of internal alkynes through a hydroamination/aza-Heck reaction sequence for the regioselective synthesis of indoles

(2007) Lutz Ackermann et al.   TETRAHEDRON

Preparation of 3-substituted-2-pyridin-2-ylindoles: regioselectivity of Larock’s indole annulation with 2-alkynylpyridines

(2007) Frank Roschangar et al.   TETRAHEDRON LETTERS