Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury

Melittin Ameliorates Endotoxin-Induced Acute Kidney Injury by Inhibiting Inflammation, Oxidative Stress, and Cell Death in Mice

(2021) Jung-Yeon Kim et al.   Oxidative Medicine and Cellular Longevity

Lansoprazole promotes cisplatin‐induced acute kidney injury via enhancing tubular necroptosis

(2021) Lin Ye et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

6‐Shogaol induces apoptosis in acute lymphoblastic leukaemia cells by targeting p53 signalling pathway and generation of reactive oxygen species

(2021) Somayeh Najafi Dorcheh et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes

(2021) Iris Bischoff-Kont et al.   Pharmaceuticals

Oxidative Stress in the Pathophysiology of Kidney Disease: Implications for Noninvasive Monitoring and Identification of Biomarkers

(2020) Marianna Gyurászová et al.   Oxidative Medicine and Cellular Longevity

7-Hydroxycoumarin protects against cisplatin-induced acute kidney injury by inhibiting necroptosis and promoting Sox9-mediated tubular epithelial cell proliferation

(2020) Wei-Feng Wu et al.   PHYTOMEDICINE

The Role of Chemokines and Chemokine Receptors in Diabetic Nephropathy

(2020) Ting-Ting Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

6-Shogaol Protects Human Melanocytes against Oxidative Stress through Activation of the Nrf2-Antioxidant Response Element Signaling Pathway

(2020) Lingli Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Roles of Nrf2 in Protecting the Kidney from Oxidative Damage

(2020) Masahiro Nezu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

6-Shogaol suppresses the growth of breast cancer cells by inducing apoptosis and suppressing autophagy via targeting notch signaling pathway

(2020) Azizah S. Bawadood et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective Effects of SPA0355, a Thiourea Analogue, Against Lipopolysaccharide-Induced Acute Kidney Injury in Mice

(2020) Jung-Yeon Kim et al.   Antioxidants

Protective Effects of Bee Venom against Endotoxemia-Related Acute Kidney Injury in Mice

(2020) Jung-Yeon Kim et al.   Biology-Basel

Isoliquiritigenin Pretreatment Induces Endoplasmic Reticulum Stress-Mediated Hormesis and Attenuates Cisplatin-Induced Oxidative Stress and Damage in LLC-PK1 Cells

(2020) Tania Gómez-Sierra et al.   MOLECULES

Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects of Apamin in a Murine Model of Lipopolysaccharide-Induced Acute Kidney Injury

(2020) Jung-Yeon Kim et al.   MOLECULES

Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

(2020) Jung-Yeon Kim et al.   Antioxidants

Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice

(2020) Jung-Yeon Kim et al.   Biomedicines

Protective Role of Natural Products in Cisplatin-Induced Nephrotoxicity

(2019) Nurul Raudzah Adib Ridzuan et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Regulated necrosis in kidney ischemia-reperfusion injury

(2019) Aspasia Pefanis et al.   KIDNEY INTERNATIONAL

RIPK1 inhibitor Cpd-71 attenuates renal dysfunction in cisplatin-treated mice via attenuating necroptosis, inflammation and oxidative stress

(2019) Jia-nan Wang et al.   CLINICAL SCIENCE

Protective effect of urolithin a on cisplatin-induced nephrotoxicity in mice via modulation of inflammation and oxidative stress

(2019) Taile Jing et al.   FOOD AND CHEMICAL TOXICOLOGY

Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

(2019) Sara J. Holditch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginger extract and its compound, 6-shogaol, attenuates painful diabetic neuropathy in mice via reducing TRPV1 and NMDAR2B expressions in the spinal cord

(2019) Fifteen Aprila Fajrin et al.   JOURNAL OF ETHNOPHARMACOLOGY

6‐Shogaol, an active ingredient of ginger, inhibits osteoclastogenesis and alveolar bone resorption in ligature‐induced periodontitis in mice

(2019) Yong‐Gun Kim et al.   JOURNAL OF PERIODONTOLOGY

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts

(2019) Nonaka et al.   MOLECULES

Farrerol Attenuates Cisplatin-Induced Nephrotoxicity by Inhibiting the Reactive Oxygen Species-Mediated Oxidation, Inflammation, and Apoptotic Signaling Pathways

(2019) Ning Ma et al.   Frontiers in Physiology

Pharmacological Activation of Sirt1 Ameliorates Cisplatin-Induced Acute Kidney Injury by Suppressing Apoptosis, Oxidative Stress, and Inflammation in Mice

(2019) Jung-Yeon Kim et al.   Antioxidants

Ginger and its bioactive component 6-shogaol mitigate lung inflammation in a murine asthma model

(2019) Gene T. Yocum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protective Effects of Melatonin Against Aristolochic Acid-Induced Nephropathy in Mice

(2019) Jung-Yeon Kim et al.   Biomolecules

6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity in db/db mice

(2018) Yun Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Neuroprotective Effects of 6-Shogaol and Its Metabolite, 6-Paradol, in a Mouse Model of Multiple Sclerosis

(2018) Arjun Sapkota et al.   Biomolecules & Therapeutics

Role of food-derived antioxidants against cisplatin induced-nephrotoxicity

(2018) Tania Gómez-Sierra et al.   FOOD AND CHEMICAL TOXICOLOGY

Necrostatin-1 Attenuates Cisplatin-Induced Nephrotoxicity Through Suppression of Apoptosis and Oxidative Stress and Retains Klotho Expression

(2018) Yichun Ning et al.   Frontiers in Pharmacology

Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice

(2018) Jung-Yeon Kim et al.   MEDIATORS OF INFLAMMATION

Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice

(2018) Zeng Qi et al.   MOLECULES

Necroptosis and Inflammation

(2016) Kim Newton et al.   Annual Review of Biochemistry

Pretreatment of 6-shogaol attenuates oxidative stress and inflammation in middle cerebral artery occlusion-induced mice

(2016) Ji-Young Na et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Antioxidants and Natural Products in Inflammation

(2016) Palanisamy Arulselvan et al.   Oxidative Medicine and Cellular Longevity

6-Shogaol, an active compound of ginger, alleviates allergic dermatitis-like skin lesions via cytokine inhibition by activating the Nrf2 pathway

(2016) Gunhyuk Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Role for Tubular Necroptosis in Cisplatin-Induced AKI

(2015) Y. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phenotype standardization for drug-induced kidney disease

(2015) Ravindra L. Mehta et al.   KIDNEY INTERNATIONAL

Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol

(2015) Shoujiao Peng et al.   Food & Function

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation

(2013) Gunhyuk Park et al.   ACTA PHARMACOLOGICA SINICA

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

(2012) I. Rahath Kubra et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

(2011) Penélope D. Sánchez-González et al.   CRITICAL REVIEWS IN TOXICOLOGY

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

(2009) Swarnalatha Dugasani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL