Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients

Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression

(2021) Diogo de Oliveira Pessoa et al.   NEOPLASIA

EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment

(2020) Yaqi Tang et al.   Cancers

Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis

(2020) Hátylas Azevedo et al.   Clinical Epigenetics

The Stress-Like Cancer Cell State Is a Consistent Component of Tumorigenesis

(2020) Maayan Baron et al.   Cell Systems

Targeting the ERK Signaling Pathway in Melanoma

(2019) Paola Savoia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gene expression and promoter methylation of angiogenic and lymphangiogenic factors as prognostic markers in melanoma

(2019) Ana Carolina Monteiro et al.   Molecular Oncology

Transcriptomic analysis reveals prognostic molecular signatures of stage I melanoma

(2019) Rohit Thakur et al.   CLINICAL CANCER RESEARCH

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape

(2019) Daniel N. Weinberg et al.   NATURE

Preclinical models for precision oncology

(2018) Maider Ibarrola-Villava et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The new 8th edition of TNM staging and its implications for skin cancer: a review by the British Association of Dermatologists and the Royal College of Pathologists, United Kingdom

(2018) S. G. Keohane et al.   BRITISH JOURNAL OF DERMATOLOGY

Toward Minimal Residual Disease-Directed Therapy in Melanoma

(2018) Florian Rambow et al.   CELL

Cutaneous Melanoma—A Long Road from Experimental Models to Clinical Outcome: A Review

(2018) Dorina Coricovac et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

(2018) Jérémie Nsengimana et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer

(2018) Maria Arechederra et al.   Nature Communications

Identification of a robust methylation classifier for cutaneous melanoma diagnosis

(2018) Kathleen Conway et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Melanoma Explorer

(2018) Dario Strbenac et al.   MELANOMA RESEARCH

DNA methylation aberrancies as a guide for surveillance and treatment of human cancers

(2017) Gangning Liang et al.   Epigenetics

The Slow Cycling Phenotype: A Growing Problem for Treatment Resistance in Melanoma

(2017) Antonio Ahn et al.   MOLECULAR CANCER THERAPEUTICS

Marked for death: targeting epigenetic changes in cancer

(2017) Sophia Xiao Pfister et al.   NATURE REVIEWS DRUG DISCOVERY

Statistical and integrative system-level analysis of DNA methylation data

(2017) Andrew E. Teschendorff et al.   NATURE REVIEWS GENETICS

Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer

(2017) K Heilmann et al.   ONCOGENE

Epigenetics of malignant melanoma

(2017) Bruce Moran et al.   SEMINARS IN CANCER BIOLOGY

Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities

(2017) Goran Micevic et al.   Clinical Epigenetics

Identification of DNA Methylation–Independent Epigenetic Events Underlying Clear Cell Renal Cell Carcinoma

(2016) Elinne Becket et al.   CANCER RESEARCH

Mitochondrial cAMP signaling

(2016) Fan Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair

(2016) Timothy Budden et al.   Oncotarget

Epigenetic regulation in human melanoma: past and future

(2015) Debina Sarkar et al.   Epigenetics

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

INPP4B is an oncogenic regulator in human colon cancer

(2015) S T Guo et al.   ONCOGENE

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

(2015) Meng Na Chi et al.   Oncotarget

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway

(2015) Seung-Hyun Hong et al.   Oncotarget

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

SGK3 Mediates INPP4B-Dependent PI3K Signaling in Breast Cancer

(2014) Jessica A. Gasser et al.   MOLECULAR CELL

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Tissue Inhibitor of Metalloproteinase 1 Expression Associated with Gene Demethylation Confers Anoikis Resistance in Early Phases of Melanocyte Malignant Transformation

(2014) Tatiana I. Ricca et al.   Translational Oncology

Interaction of LRRK2 with kinase and GTPase signaling cascades

(2014) Joon Y. Boon et al.   Frontiers in Molecular Neuroscience

Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity

(2014) Niels Vandamme et al.   Frontiers in Oncology

A Tumor Suppressor Function for the Lipid Phosphatase INPP4B in Melanocytic Neoplasms

(2013) Rolando Perez-Lorenzo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation

(2013) Mariana Toricelli et al.   Molecular Cancer

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Mining Gene Expression Signature for the Detection of Pre-Malignant Melanocytes and Early Melanomas with Risk for Metastasis

(2012) Camila Ferreira de Souza et al.   PLoS One

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

(2012) Altuna Akalin et al.   GENOME BIOLOGY

Epigenetic reprogramming as a key contributor to melanocyte malignant transformation

(2011) Fernanda Molognoni et al.   Epigenetics

SLIM: a sliding linear model for estimating the proportion of true null hypotheses in datasets with dependence structures

(2010) Hong-Qiang Wang et al.   BIOINFORMATICS

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

Cancer stem cells versus phenotype-switching in melanoma

(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

(2009) D. Bogunovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA