Cancer stem cells versus phenotype-switching in melanoma

Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell

(2010) M. A. Held et al.   CANCER RESEARCH

Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

(2010) T. Schatton et al.   CANCER RESEARCH

Microphthalmia-Associated Transcription Factor Controls the DNA Damage Response and a Lineage-Specific Senescence Program in Melanomas

(2010) Sandy Giuliano et al.   CANCER RESEARCH

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

(2010) Sonja J. Heidorn et al.   CELL

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Key Roles for Transforming Growth Factor β in Melanocyte Stem Cell Maintenance

(2010) Emi K. Nishimura et al.   Cell Stem Cell

Hypoxia upregulates adhesion ability to peritoneum through a transforming growth factor-β-dependent mechanism in diffuse-type gastric cancer cells

(2010) Satoru Noda et al.   EUROPEAN JOURNAL OF CANCER

Enhanced fibrillin-2 expression is a general feature of wound healing and sclerosis: potential alteration of cell attachment and storage of TGF-β

(2010) Jürgen Brinckmann et al.   LABORATORY INVESTIGATION

Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms

(2010) Bryan L. Copple   LIVER INTERNATIONAL

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

A role for the JARID1B stem cell marker for continuous melanoma growth

(2010) Matthew Held et al.   Pigment Cell & Melanoma Research

Melanoma stem cells - are there devils in the detail?

(2010) Mark Shackleton   Pigment Cell & Melanoma Research

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene

(2010) Dominique Kobi et al.   Pigment Cell & Melanoma Research

Adult Stem Cells Exhibit Global Suppression of RNA Polymerase II Serine-2 Phosphorylation

(2010) Rasmus Freter et al.   STEM CELLS

Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes

(2009) Chelsea C. Pinnix et al.   CANCER RESEARCH

Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

(2009) S. Pinner et al.   CANCER RESEARCH

Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin

(2009) Igor Adameyko et al.   CELL

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours

(2009) Amy Brock et al.   NATURE REVIEWS GENETICS

Epigenetic responses to environmental change and their evolutionary implications

(2009) B. M. Turner   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sphingolipid-mediated restoration of Mitf expression and repigmentation in vivo in a mouse model of hair graying

(2009) Bidisha Saha et al.   Pigment Cell & Melanoma Research

Transgenic expression of Notch in melanocytes demonstrates RBP-Jκ-dependent signaling

(2009) Karine Schouwey et al.   Pigment Cell & Melanoma Research

Frequent mutations in the MITF pathway in melanoma

(2009) Julia C. Cronin et al.   Pigment Cell & Melanoma Research

Dormancy of metastatic melanoma

(2009) Liliana Ossowski et al.   Pigment Cell & Melanoma Research

Fifteen-year quest for microphthalmia-associated transcription factor target genes

(2009) Yann Cheli et al.   Pigment Cell & Melanoma Research

The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma

(2009) SubbaRao V. Madhunapantula et al.   Pigment Cell & Melanoma Research

The Increasing Complexity of the Cancer Stem Cell Paradigm

(2009) J. M. Rosen et al.   SCIENCE

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

(2008) D. C. Taussig et al.   BLOOD

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

(2008) J. Goodall et al.   CANCER RESEARCH

Notch1 is an effector of Akt and hypoxia in melanoma development

(2008) Barbara Bedogni et al.   JOURNAL OF CLINICAL INVESTIGATION

Melanoma Stem Cells: The Dark Seed of Melanoma

(2008) Susan E. Zabierowski et al.   JOURNAL OF CLINICAL ONCOLOGY

Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles

(2008) Geneviève Aubin-Houzelstein et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage

(2008) Satoru Yokoyama et al.   Pigment Cell & Melanoma Research

Ultraviolet wavebands and melanoma initiation

(2008) Dorothy C. Bennett   Pigment Cell & Melanoma Research

POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis

(2008) Anthony L. Cook et al.   Pigment Cell & Melanoma Research

The making of a melanocyte: the specification of melanoblasts from the neural crest

(2008) Aaron J. Thomas et al.   Pigment Cell & Melanoma Research

Transforming growth factor-β in cutaneous melanoma

(2008) Delphine Javelaud et al.   Pigment Cell & Melanoma Research

Epigenetic marks in melanoma

(2008) Hunter W. Richards et al.   Pigment Cell & Melanoma Research

Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF

(2008) Claudia Wellbrock et al.   PLoS One