Investigating the Effect of Inosine on Brain Purinergic Receptors and Neurotrophic and Neuroinflammatory Parameters in an Experimental Model of Alzheimer’s Disease

The protective effect of inosine against rotenone-induced Parkinson’s disease in mice; role of oxido-nitrosative stress, ERK phosphorylation, and A2AR expression

(2020) Marwa E. A. El-Shamarka et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Tannic Acid Ameliorates STZ-Induced Alzheimer’s Disease-Like Impairment of Memory, Neuroinflammation, Neuronal Death and Modulates Akt Expression

(2020) Mariana F. B. Gerzson et al.   NEUROTOXICITY RESEARCH

Synaptic Activity and (Neuro)Inflammation in Alzheimer’s Disease: Could Exosomes be an Additional Link?

(2020) Hermine Counil et al.   JOURNAL OF ALZHEIMERS DISEASE

Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease

(2020) D. Allan Butterfield et al.   NEUROBIOLOGY OF DISEASE

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

(2020) Harald Hampel et al.   Frontiers in Immunology

Mast Cells in Stress, Pain, Blood-Brain Barrier, Neuroinflammation and Alzheimer’s Disease

(2019) Duraisamy Kempuraj et al.   Frontiers in Cellular Neuroscience

APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease

(2019) Annah M. Moore et al.   NEUROBIOLOGY OF AGING

Inosine protects against impairment of memory induced by experimental model of Alzheimer disease: a nucleoside with multitarget brain actions

(2019) Fernanda Cardoso Teixeira et al.   PSYCHOPHARMACOLOGY

Alzheimer’s Disease Pharmacotherapy in Relation to Cholinergic System Involvement

(2019) Gabriela Dumitrita Stanciu et al.   Biomolecules

Electrochemical detection of specific interactions between apolipoprotein E isoforms and DNA sequences related to Alzheimer’s disease

(2019) Dhésmon Lima et al.   BIOELECTROCHEMISTRY

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

(2018) Harald Hampel et al.   BRAIN

Anthocyanins as a potential pharmacological agent to manage memory deficit, oxidative stress and alterations in ion pump activity induced by experimental sporadic dementia of Alzheimer's type

(2018) Simone Muniz Pacheco et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Blockade of adenosine A 2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

(2018) António C. Silva et al.   NEUROBIOLOGY OF DISEASE

Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis

(2018) Chiara Rossi et al.   Cell Death & Disease

BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders

(2018) Ting Shen et al.   Aging and Disease

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

(2018) Emilie Faivre et al.   Frontiers in Molecular Neuroscience

Inosine improves cognitive function and decreases aging-induced oxidative stress and neuroinflammation in aged female rats

(2018) Poonam Ruhal et al.   INFLAMMOPHARMACOLOGY

Comparative study on the effects of cigarette smoke exposure, ethanol consumption and association: behavioral parameters, apoptosis, glial fibrillary acid protein and S100β immunoreactivity in different regions of the rat hippocampus

(2018) Fernanda Huf et al.   ALCOHOL

Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration

(2017) et al.   MOLECULES

Inflammatory Aspects of Alzheimer Disease and Other Neurodegenerative Disorders

(2017) Claudia Schwab et al.   JOURNAL OF ALZHEIMERS DISEASE

Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor

(2016) Stella Célio Junqueira et al.   MOLECULAR NEUROBIOLOGY

Purinergic receptors as potential therapeutic targets in Alzheimer's disease

(2016) Lucas T. Woods et al.   NEUROPHARMACOLOGY

Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimer’s-like dementia: Involvement of acetylcholinesterase and cell death

(2016) Juliana Sorraila de Oliveira et al.   NEUROTOXICOLOGY

Adenosine A2Areceptors are necessary and sufficient to trigger memory impairment in adult mice

(2015) N Pagnussat et al.   BRITISH JOURNAL OF PHARMACOLOGY

Staging of cognitive deficits and neuropathological and ultrastructural changes in streptozotocin-induced rat model of Alzheimer’s disease

(2015) Ana Knezovic et al.   JOURNAL OF NEURAL TRANSMISSION

Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant Mechanism

(2015) Paweł Grieb   MOLECULAR NEUROBIOLOGY

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Inosine improves functional recovery after experimental traumatic brain injury

(2014) Shlomit Dachir et al.   BRAIN RESEARCH

Status of Acetylcholinesterase and Butyrylcholinesterase in Alzheimer's Disease and Type 2 Diabetes Mellitus

(2014) Gohar Mushtaq et al.   CNS & Neurological Disorders-Drug Targets

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

(2014) André Jerónimo-Santos et al.   NEUROPHARMACOLOGY

Oral administration of inosine produces antidepressant-like effects in mice

(2014) Junko Muto et al.   Scientific Reports

Anthocyanins restore behavioral and biochemical changes caused by streptozotocin-induced sporadic dementia of Alzheimer's type

(2013) Jessié M. Gutierres et al.   LIFE SCIENCES

Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease

(2013) Willem Kamphuis et al.   NEUROBIOLOGY OF AGING

Anti-inflammatory effects of inosine in allergic lung inflammation in mice: evidence for the participation of adenosine A2A and A3 receptors

(2013) Fernanda da Rocha Lapa et al.   Purinergic Signalling

IL-4 in the Brain: A Cytokine To Remember

(2012) Sachin P. Gadani et al.   JOURNAL OF IMMUNOLOGY

What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer’s disease, about the therapeutic strategies in Alzheimer’s research

(2012) Melita Salkovic-Petrisic et al.   JOURNAL OF NEURAL TRANSMISSION

Cholesterol Level and Statin Use in Alzheimer Disease

(2011) Nina E. Shepardson   ARCHIVES OF NEUROLOGY

Astrocytes: Implications for Neuroinflammatory Pathogenesis of Alzheimers Disease

(2011) Chuanyu Li et al.   Current Alzheimer Research

Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons

(2011) Sung E. Kwon et al.   NEURON

Role of Adenosine A2AReceptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease

(2011) Maria Teresa Tebano et al.   TheScientificWorldJOURNAL

Modulation of brain-derived neurotrophic factor (BDNF) actions in the nervous system by adenosine A2A receptors and the role of lipid rafts

(2010) Ana M. Sebastião et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Role of Adenosine in Alzheimers Disease

(2009) Anisur Rahman   Current Neuropharmacology

The Treatment of Multiple Sclerosis with Inosine

(2009) Clyde E. Markowitz et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

(2007) Yuan Lu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY