Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
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Title
Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
Authors
Keywords
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Journal
Frontiers in Molecular Neuroscience
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-07-12
DOI
10.3389/fnmol.2018.00235
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- (2018) António C. Silva et al. NEUROBIOLOGY OF DISEASE
- Long-term Treatment with Low-Dose Caffeine Worsens BPSD-Like Profile in 3xTg-AD Mice Model of Alzheimer’s Disease and Affects Mice with Normal Aging
- (2018) Raquel Baeta-Corral et al. Frontiers in Pharmacology
- Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?
- (2018) Cyril Laurent et al. Biomedical Journal
- Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease
- (2017) Emrin Horgusluoglu-Moloch et al. NEUROBIOLOGY OF AGING
- Deletion of exons 9 and 10 of the Presenilin 1 gene in a patient with Early-onset Alzheimer Disease generates longer amyloid seeds
- (2017) Kilan Le Guennec et al. NEUROBIOLOGY OF DISEASE
- Adenosine A2A receptor inactivation alleviates early-onset cognitive dysfunction after traumatic brain injury involving an inhibition of tau hyperphosphorylation
- (2017) Z-A Zhao et al. Translational Psychiatry
- Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice
- (2017) Chuanhai Cao et al. JOURNAL OF ALZHEIMERS DISEASE
- Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice
- (2017) Gary W. Arendash et al. JOURNAL OF ALZHEIMERS DISEASE
- How does adenosine control neuronal dysfunction and neurodegeneration?
- (2016) Rodrigo A. Cunha JOURNAL OF NEUROCHEMISTRY
- Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond
- (2016) Elise Cuyvers et al. LANCET NEUROLOGY
- Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses
- (2016) Nuno J. Machado et al. MOLECULAR NEUROBIOLOGY
- Altered motility of plaque-associated microglia in a model of Alzheimer’s disease
- (2016) Stefka Gyoneva et al. NEUROSCIENCE
- Early synaptic deficits in the APP/PS1 mouse model of Alzheimer’s disease involve neuronal adenosine A2A receptors
- (2016) Silvia Viana da Silva et al. Nature Communications
- An Anti-Parkinson’s Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity
- (2016) Jing Lu et al. PLoS One
- The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function
- (2016) Vânia L. Batalha et al. Scientific Reports
- PART is part of Alzheimer disease
- (2015) Charles Duyckaerts et al. ACTA NEUROPATHOLOGICA
- Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia
- (2015) Marco Matos et al. BIOLOGICAL PSYCHIATRY
- Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease
- (2015) J. C. Savage et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
- (2015) P Li et al. MOLECULAR PSYCHIATRY
- Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory
- (2015) Anna G Orr et al. NATURE NEUROSCIENCE
- Caffeine acts through neuronal adenosine A2Areceptors to prevent mood and memory dysfunction triggered by chronic stress
- (2015) Manuella P. Kaster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory
- (2015) Elodie Marciniak et al. Scientific Reports
- From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?
- (2014) Vanessa Flaten et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- A2A adenosine receptor deletion is protective in a mouse model of Tauopathy
- (2014) C Laurent et al. MOLECULAR PSYCHIATRY
- Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology
- (2014) Cyril Laurent et al. NEUROBIOLOGY OF AGING
- Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease
- (2014) Stefka Gyoneva et al. NEUROBIOLOGY OF DISEASE
- Hydrogen Sulfide Inhibits A2A Adenosine Receptor Agonist Induced β-Amyloid Production in SH-SY5Y Neuroblastoma Cells via a cAMP Dependent Pathway
- (2014) Bhushan Vijay Nagpure et al. PLoS One
- Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release
- (2014) Özgür Genç et al. eLife
- Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
- (2013) Grietje Krabbe et al. PLoS One
- A1R–A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes
- (2013) Sofia Cristóvão-Ferreira et al. Purinergic Signalling
- Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease
- (2012) Tae-Kyung Kim et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes
- (2012) Marco Matos et al. GLIA
- Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation
- (2012) V L Batalha et al. MOLECULAR PSYCHIATRY
- NTPDase1 activity attenuates microglial phagocytosis
- (2012) Larisa Bulavina et al. Purinergic Signalling
- Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease
- (2011) Wei Zhang et al. BEHAVIOURAL BRAIN RESEARCH
- Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction
- (2011) Nelson Rebola et al. JOURNAL OF NEUROCHEMISTRY
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- At the junction of SNARE and SM protein function
- (2010) Chavela M Carr et al. CURRENT OPINION IN CELL BIOLOGY
- Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by -Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway
- (2009) P. M. Canas et al. JOURNAL OF NEUROSCIENCE
- Adenosine A2A receptor mediates microglial process retraction
- (2009) Anna G Orr et al. NATURE NEUROSCIENCE
- Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX
- (2009) Lyndsey E. Collins et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A2A receptor knockout mice with microarray profiling
- (2009) Liqun Yu et al. PHYSIOLOGICAL GENOMICS
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