Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant Mechanism

Modeling Sporadic Alzheimer's Disease: The Insulin Resistant Brain State Generates Multiple Long-Term Morphobiological Abnormalities Including Hyperphosphorylated Tau Protein and Amyloid-β

(2017) Melita Salkovic-Petrisic et al.   JOURNAL OF ALZHEIMERS DISEASE

Is Insulin Resistant Brain State a Central Feature of the Metabolic-Cognitive Syndrome?

(2017) Vincenza Frisardi et al.   JOURNAL OF ALZHEIMERS DISEASE

Brain metabolic dysfunction at the core of Alzheimer's disease

(2014) Suzanne M. de la Monte et al.   BIOCHEMICAL PHARMACOLOGY

Within-patient correspondence of amyloid-β and intrinsic network connectivity in Alzheimer’s disease

(2014) Nicholas Myers et al.   BRAIN

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease

(2013) Sonia C. Correia et al.   Current Alzheimer Research

Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes

(2013) Li Liu et al.   EXPERIMENTAL NEUROLOGY

Review article What causes alzheimer’s disease?

(2013) Richard A. Armstrong   FOLIA NEUROPATHOLOGICA

Hepatic glucose sensing is required to preserve β cell glucose competence

(2013) Pascal Seyer et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of amyloid β in the pathogenesis of Alzheimer's disease

(2013) Barnabas James Gilbert   JOURNAL OF CLINICAL PATHOLOGY

Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain

(2013) Fanny Langlet et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice

(2013) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Glial activation and post-synaptic neurotoxicity: The key events in Streptozotocin (ICV) induced memory impairment in rats

(2013) Shivika Rai et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease

(2012) Chaoyun Li et al.   AGEING RESEARCH REVIEWS

Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

(2012) D. Lanfray et al.   DIABETES

What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer’s disease, about the therapeutic strategies in Alzheimer’s research

(2012) Melita Salkovic-Petrisic et al.   JOURNAL OF NEURAL TRANSMISSION

A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse)

(2012) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Insulin in the brain: There and back again

(2012) William A. Banks et al.   PHARMACOLOGY & THERAPEUTICS

Early and late neurodegeneration and memory disruption after intracerebroventricular streptozotocin

(2012) Taisa de Oliveira Santos et al.   PHYSIOLOGY & BEHAVIOR

In Vivo Cross-sectional Characterization of Cerebral Alterations Induced by Intracerebroventricular Administration of Streptozotocin

(2012) Audrey Kraska et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

(2011) Sónia C. Correia et al.   AGEING RESEARCH REVIEWS

ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor

(2011) Gunjan Saxena et al.   BEHAVIOURAL BRAIN RESEARCH

Brain glucose sensing and neural regulation of insulin and glucagon secretion

(2011) B. Thorens   DIABETES OBESITY & METABOLISM

Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer’s disease: a long-term follow up study

(2011) Melita Salkovic-Petrisic et al.   JOURNAL OF NEURAL TRANSMISSION

Alzheimer’s Disease Pathologic Cascades: Who Comes First, What Drives What

(2011) Russell H. Swerdlow   NEUROTOXICITY RESEARCH

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

(2011) Diana W Shineman et al.   Alzheimers Research & Therapy

Glial Glucokinase Expression in Adult and Post-Natal Development of the Hypothalamic Region

(2010) Carola Millán et al.   ASN Neuro

Chemotherapy with 5-fluorouracil, cisplatin and streptozocin for neuroendocrine tumours

(2010) N C Turner et al.   BRITISH JOURNAL OF CANCER

Causes versus effects: the increasing complexities of Alzheimer’s disease pathogenesis

(2010) Siddhartha Mondragón-Rodríguez et al.   Expert Review of Neurotherapeutics

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

(2010) Andrei G. Vlassenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

‘Too much good news’ – are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?

(2010) Kathleen R. Zahs et al.   TRENDS IN NEUROSCIENCES

Brain glucose transporter protein 2 and sporadic Alzheimer’s disease

(2010) Melita Šalković-Petrišić et al.   Translational Neuroscience

Dysregulation of Insulin Signaling, Glucose Transporters, O -GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain

(2009) Yanqiu Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

(2009) Leslie Crews et al.   Brain Structure & Function

Of Mice and Men

(2009) Hugo Geerts   CNS DRUGS

Antioxidant capacity in rat brain after ICV treatment with streptozotocin and alloxan — a preliminary study

(2009) A. Sapcanin et al.   NEUROTOXICITY RESEARCH

Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative–nitrosative stress in rats

(2009) Vinod Tiwari et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Intracerebroventricular Administration of Drugs

(2009) Aaron M Cook et al.   PHARMACOTHERAPY

Free fatty acids and skeletal muscle insulin resistance

(2008) Edward W Kraegen et al.   CURRENT OPINION IN LIPIDOLOGY

Hippocampal hypometabolism predicts cognitive decline from normal aging

(2007) Lisa Mosconi et al.   NEUROBIOLOGY OF AGING