Targeting HNRNPU to overcome cisplatin resistance in bladder cancer

The association of Neurofibromatosis Type 1 and lower urinary tract dysfunction in the paediatric population – A critical review of literature

(2020) Bruce Gao et al.   Journal of Pediatric Urology

Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells

(2019) Jesse Bakke et al.   BMC CANCER

Evaluation of rare and common variants from suspected familial or sporadic nasopharyngeal carcinoma (NPC) susceptibility genes in sporadic NPC

(2019) Zhiwei Liu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Molecular and histopathology directed therapy for advanced bladder cancer

(2019) Constantine Alifrangis et al.   Nature Reviews Urology

hnRNPU/TrkB defines a chromatin accessibility checkpoint for liver injury and NASH pathogenesis

(2019) Jing Xiong et al.   HEPATOLOGY

WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating

(2019) Barbara A. Scholz et al.   NATURE GENETICS

Systematic analysis of survival‐associated alternative splicing signatures in clear cell renal cell carcinoma

(2019) Tao Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer

(2019) Sunwang Xu et al.   Nature Communications

Possible Molecular Markers for the Diagnosis of Pancreatic Ductal Adenocarcinoma

(2018) Quan Shen et al.   MEDICAL SCIENCE MONITOR

CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma

(2018) Michal Alon et al.   Oncotarget

Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement

(2018) Guangshuai Jia et al.   Nature Communications

A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer

(2018) Andrew Goodspeed et al.   EUROPEAN UROLOGY

MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis

(2017) Celia S. L. Mak et al.   Molecular Cancer

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer

(2017) David Liu et al.   Nature Communications

Long noncoding RNA SFTA1P promoted apoptosis and increased cisplatin chemosensitivity via regulating the hnRNP-U-GADD45A axis in lung squamous cell carcinoma

(2017) Ling Li et al.   Oncotarget

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Bladder cancer

(2017) Oner Sanli et al.   Nature Reviews Disease Primers

Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin

(2017) Xing Wang et al.   Scientific Reports

High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells

(2016) Sina Oppermann et al.   BLOOD

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

On a FOX hunt: functions of FOX transcriptional regulators in bladder cancer

(2016) Hironobu Yamashita et al.   Nature Reviews Urology

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

(2016) Konstantinos Tzelepis et al.   Cell Reports

Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy

(2014) Woonyoung Choi et al.   CANCER CELL

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

CD147 and MCT1-potential partners in bladder cancer aggressiveness and cisplatin resistance

(2014) Julieta Afonso et al.   MOLECULAR CARCINOGENESIS

Reduced NF1 Expression Confers Resistance to EGFR Inhibition in Lung Cancer

(2014) E. C. de Bruin et al.   Cancer Discovery

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Molecular mechanisms of cisplatin resistance in bladder cancer

(2012) Ross M Drayton et al.   Expert Review of Anticancer Therapy

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

Elucidating Distinct Roles for NF1 in Melanomagenesis

(2012) Ophélia Maertens et al.   Cancer Discovery

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Forkhead box O-class 1 and Forkhead box G1 as Prognostic Markers for Bladder Cancer

(2009) Tae-Hwan Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE