WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating

β-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells

(2018) Oksana Voloshanenko et al.   Scientific Reports

Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism

(2018) Jurian Schuijers et al.   Cell Reports

Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability

(2018) Maike M.K. Hansen et al.   Cell Systems

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

(2018) Yulong Su et al.   GENES & DEVELOPMENT

Causes and consequences of nuclear gene positioning

(2017) Sigal Shachar et al.   JOURNAL OF CELL SCIENCE

Wnt/beta-catenin pathway: modulating anticancer immune response

(2017) Sachin Gopalkrishna Pai et al.   Journal of Hematology & Oncology

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

(2017) Pau Pascual-Garcia et al.   MOLECULAR CELL

Recent evidence that TADs and chromatin loops are dynamic structures

(2017) Anders S. Hansen et al.   Nucleus

Recent evidence that TADs and chromatin loops are dynamic structures

(2017) Anders S. Hansen et al.   Nucleus

Nucleoporin-mediated regulation of cell identity genes

(2016) Arkaitz Ibarra et al.   GENES & DEVELOPMENT

MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase

(2016) Valeriya Posternak et al.   MOLECULAR CANCER RESEARCH

Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells

(2016) Lars Tögel et al.   MOLECULAR CANCER THERAPEUTICS

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

(2016) Andrew P. Feinberg et al.   NATURE REVIEWS GENETICS

A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity

(2016) Luca Fagnocchi et al.   Nature Communications

Chromatinin situproximity (ChrISP): Single-cell analysis of chromatin proximities at a high resolution

(2016) Xingqi Chen et al.   BIOTECHNIQUES

The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments

(2015) Thomas Cremer et al.   FEBS LETTERS

PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription

(2015) Honglei Zhao et al.   MOLECULAR CELL

Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

(2015) Denes Hnisz et al.   MOLECULAR CELL

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

(2015) Philipp Rathert et al.   NATURE

dbSUPER: a database of super-enhancers in mouse and human genome

(2015) Aziz Khan et al.   NUCLEIC ACIDS RESEARCH

Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin

(2015) Michal Schwartz et al.   Nucleus

Super Enhancers in Cancers, Complex Disease, and Developmental Disorders

(2015) Adrienne Niederriter et al.   Genes

Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin

(2015) Michal Schwartz et al.   Nucleus

Nuclear pores as versatile platforms for gene regulation

(2014) Pau Pascual-Garcia et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The visualization of large organized chromatin domains enriched in the H3K9me2 mark within a single chromosome in a single cell

(2014) Xingqi Chen et al.   Epigenetics

From Hypothesis to Mechanism: Uncovering Nuclear Pore Complex Links to Gene Expression

(2014) L. T. Burns et al.   MOLECULAR AND CELLULAR BIOLOGY

Can we safely target the WNT pathway?

(2014) Michael Kahn   NATURE REVIEWS DRUG DISCOVERY

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Genome Architecture: Domain Organization of Interphase Chromosomes

(2013) Wendy A. Bickmore et al.   CELL

Dynamic Association of NUP98 with the Human Genome

(2013) Yun Liang et al.   PLoS Genetics

Dynamic Organization of Transcription Compartments Is Dependent on Functional Nuclear Architecture

(2012) Shovamayee Maharana et al.   BIOPHYSICAL JOURNAL

Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors

(2012) I. K. Sur et al.   SCIENCE

Transcription factories, chromatin loops, and the dysregulation of gene expression in malignancy

(2012) Binwei Deng et al.   SEMINARS IN CANCER BIOLOGY

Higher order chromatin organization in cancer

(2012) Karen L. Reddy et al.   SEMINARS IN CANCER BIOLOGY

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

(2011) Oliver G McDonald et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes

(2010) Maya Capelson et al.   CELL

Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase

(2010) Kazuhiro Maeshima et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Does CTCF mediate between nuclear organization and gene expression?

(2009) Rolf Ohlsson et al.   BIOESSAYS

Nonallelic transvection of multiple imprinted loci is organized by theH19imprinting control region during germline development

(2009) Kuljeet Singh Sandhu et al.   GENES & DEVELOPMENT

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

(2009) Bo Wen et al.   NATURE GENETICS

Epigenetic regulation of TTF-I-mediated promoter–terminator interactions of rRNA genes

(2008) Attila Németh et al.   EMBO JOURNAL

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

High-resolution circular chromosome conformation capture assay

(2008) Anita Göndör et al.   Nature Protocols