General Synthesis of N-Trifluoromethyl Compounds with N-Trifluoromethyl Hydroxylamine Reagents

Organoiodine-Catalyzed Enantioselective Intermolecular Oxyamination of Alkenes

(2021) Chisato Wata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of N-perfluoroalkyl-3,4-disubstituted pyrroles by rhodium-catalyzed transannulation of N-fluoroalkyl-1,2,3-triazoles with terminal alkynes

(2021) Olga Bakhanovich et al.   Beilstein Journal of Organic Chemistry

Current Landscape and Future Perspective of Oxazolidinone Scaffolds Containing Antibacterial Drugs

(2021) Qianqian Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thiocarbamoyl Fluoride Synthesis by Deconstructive Diversification of Arylated Tetrahydroisoquinolines

(2021) Wentao Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of N-CF3 Alkynamides and Derivatives Enabled by Ni-Catalyzed Alkynylation of N-CF3 Carbamoyl Fluorides

(2021) Christian D.-T. Nielsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of N-trifluoromethyl amides from carboxylic acids

(2021) Jianbo Liu et al.   Chem

An N ‐Trifluoromethylation/Cyclization Strategy for Accessing Diverse N ‐Trifluoromethyl Azoles from Nitriles and 1,3‐Dipoles

(2021) Ru Zhong Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Access to AgOCF 3 and Its New Applications as a Reservoir for OCF 2 for the Direct Synthesis of N−CF 3 , Aryl or Alkyl Carbamoyl Fluorides

(2020) Abdurrahman Turksoy et al.   CHEMISTRY-A EUROPEAN JOURNAL

N ‐Trifluoromethyl Hydrazines, Indoles and Their Derivatives

(2020) Samir Bouayad‐Gervais et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)‐η3‐allyl complexes bearing N‐trifluoromethyl N‐heterocyclic carbenes:a new generation of anticancer agents which restrain the growth of high grade serous ovarian cancer tumoroids

(2020) Fabiano Visentin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Silver‐Mediated N ‐Trifluoromethylation of Amides and Peptides

(2020) Zhenzhen Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Metabolic and Pharmaceutical Aspects of Fluorinated Compounds

(2020) Benjamin M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Contribution of Organofluorine Compounds to Pharmaceuticals

(2020) Munenori Inoue et al.   ACS Omega

Current Contributions of Organofluorine Compounds to the Agrochemical Industry

(2020) Yuta Ogawa et al.   iScience

Recent advances in new trifluoromethoxylation reagents

(2019) Xiaofei Zhang et al.   Science China-Chemistry

Synthesis of Tri- and Difluoromethoxylated Compounds by Visible-Light Photoredox Catalysis

(2019) Johnny W. Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Synthesis of Thiocarbamoyl Fluorides and Trifluoromethylamines Through Fluorinative Desulfurization

(2019) Killian Onida et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas

(2019) Thomas Scattolin et al.   NATURE

A Radical Revolution for Trifluoromethoxylation

(2018) Basudev Sahoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A rhodium-catalyzed transannulation of N-(per)fluoroalkyl-1,2,3-triazoles under microwave conditions – a general route to N-(per)fluoroalkyl-substituted five-membered heterocycles

(2018) Vladimir Motornov et al.   CHEMICAL COMMUNICATIONS

Hydroxylamine Derivatives as Nitrogen-Radical Precursors in Visible-Light Photochemistry

(2018) Jacob Davies et al.   CHEMISTRY-A EUROPEAN JOURNAL

The main and recent syntheses of the N -CF 3 motif

(2018) Thierry Milcent et al.   COMPTES RENDUS CHIMIE

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Chloro(phenyl)trifluoromethyliodane and Catalyst-Free Electrophilic Trifluoromethylations

(2018) Cong Xu et al.   ORGANIC LETTERS

Exploiting and Understanding the Selectivity of Ru-N-Heterocyclic Carbene Metathesis Catalysts for the Ethenolysis of Cyclic Olefins to α,ω-Dienes

(2017) Pascal S. Engl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

(2017) Pounami Samadder et al.   MOLECULAR CANCER THERAPEUTICS

N-Trifluoromethylation of Nitrosoarenes with Sodium Triflinate

(2017) Angela van der Werf et al.   ORGANIC LETTERS

Photochemical Generation of Nitrogen-Centered Amidyl, Hydrazonyl, and Imidyl Radicals: Methodology Developments and Catalytic Applications

(2017) Markus D. Kärkäs   ACS Catalysis

Azidoperfluoroalkanes: Synthesis and Application in Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

(2016) Zsófia E. Blastik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Trifluoromethyl Amines through a Formal Umpolung Strategy from the Bench-Stable Precursor (Me4 N)SCF3

(2016) Thomas Scattolin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Approaches to Trifluoromethoxy-Substituted Compounds

(2016) Anis Tlili et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible light photoredox-controlled reactions of N-radicals and radical ions

(2016) Jia-Rong Chen et al.   CHEMICAL SOCIETY REVIEWS

State-of-the-Art in Electrophilic Trifluoromethylthiolation Reagents

(2016) Hélène Chachignon et al.   CHINESE JOURNAL OF CHEMISTRY

New entries toward the synthesis of OCF3-containing molecules

(2016) Tatiana Besset et al.   Organic Chemistry Frontiers

Isolation and Reactivity of Trifluoromethyl Iodonium Salts

(2016) Johnathan N. Brantley et al.   ACS Central Science

Shelf-Stable Electrophilic Reagents for Trifluoromethylthiolation

(2015) Xinxin Shao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Silver-Mediated Oxidative Trifluoromethylation of Phenols: Direct Synthesis of Aryl Trifluoromethyl Ethers

(2015) Jian-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrophilic Amination of Fluoroalkyl Groups on Azodicarboxylate Derivatives

(2015) Marius Mamone et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrophilic N-Trifluoromethylation of N–H Ketimines

(2015) Gang Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Mediated Oxidative Trifluoromethylation of Alcohols to Alkyl Trifluoromethyl Ethers

(2015) Jian-Bo Liu et al.   ORGANIC LETTERS

Silver-Mediated N-Trifluoromethylation of Sulfoximines

(2015) Fan Teng et al.   ORGANIC LETTERS

Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

(2014) Lingling Chu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Direct Trifluoromethylthiolation Reactions: The “Renaissance” of an Old Concept

(2014) Fabien Toulgoat et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Iron(II)-Catalyzed Intermolecular Amino-Oxygenation of Olefins through the N–O Bond Cleavage of Functionalized Hydroxylamines

(2014) Deng-Fu Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Direct Electrophilic N-Trifluoromethylation of Azoles by a Hypervalent Iodine Reagent

(2012) Katrin Niedermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organic fluorine compounds: a great opportunity for enhanced materials properties

(2011) Ricarda Berger et al.   CHEMICAL SOCIETY REVIEWS

A Ritter-Type Reaction: Direct Electrophilic Trifluoromethylation at Nitrogen Atoms Using Hypervalent Iodine Reagents

(2010) Katrin Niedermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ynamides: A Modern Functional Group for the New Millennium

(2010) Kyle A. DeKorver et al.   CHEMICAL REVIEWS

Disubstituted Azidotetrazoles as Energetic Compounds

(2009) Takashi Abe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Toward the Synthesis of the RareN-(Trifluoromethyl)amides and theN-(Difluoromethylene)-N-(trifluoromethyl)amines [RN(CF3)CF2R′] Using BrF3

(2009) Youlia Hagooly et al.   JOURNAL OF ORGANIC CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS