Silver-Mediated Oxidative Trifluoromethylation of Phenols: Direct Synthesis of Aryl Trifluoromethyl Ethers

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Fundamental Studies and Development of Nickel-Catalyzed Trifluoromethylthiolation of Aryl Chlorides: Active Catalytic Species and Key Roles of Ligand and Traceless MeCN Additive Revealed

(2015) Guoyin Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated N-Trifluoromethylation of Sulfoximines

(2015) Fan Teng et al.   ORGANIC LETTERS

Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

(2014) Lingling Chu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Trifluoromethylthiosaccharin: An Easily Accessible, Shelf-Stable, Broadly Applicable Trifluoromethylthiolating Reagent

(2014) Chunfa Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Catalytic Trifluoromethylthiolation of Boronic Acids and Alkynes Employing Electrophilic Shelf-StableN-(trifluoromethylthio)phthalimide

(2014) Roman Pluta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethoxylation of Arenes: Synthesis ofortho-Trifluoromethoxylated Aniline Derivatives by OCF3Migration

(2014) Katarzyna N. Hojczyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Addition of CF3 across unsaturated moieties: a powerful functionalization tool

(2014) Estíbaliz Merino et al.   CHEMICAL SOCIETY REVIEWS

Trifluoromethyl Ethers and –Thioethers as Tools for Medicinal Chemistry and Drug Discovery

(2014) Gregory Landelle et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Direct Trifluoromethylthiolation Reactions: The “Renaissance” of an Old Concept

(2014) Fabien Toulgoat et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Sandmeyer Trifluoromethylation of Arenediazonium Tetrafluoroborates

(2013) Grégory Danoun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-catalysed trifluoromethylation of arenes at room temperature

(2013) Sangwon Seo et al.   CHEMICAL COMMUNICATIONS

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Copper-Promoted Sandmeyer Trifluoromethylation Reaction

(2013) Jian-Jun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethylation–Iodination of Arynes

(2013) Yuwen Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethylation of Aryldiazonium Salts: Conversion of Amino Group into Trifluoromethyl Group

(2013) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethanesulfonyl Hypervalent Iodonium Ylide for Copper-Catalyzed Trifluoromethylthiolation of Enamines, Indoles, and β-Keto Esters

(2013) Yu-Dong Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed One-Pot Trifluoromethylation/Aryl Migration/Desulfonylation and C(sp2)–N Bond Formation of Conjugated Tosyl Amides

(2013) Wangqing Kong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging

(2013) Mickael Huiban et al.   Nature Chemistry

Selective C-H Fluorination of Pyridines and Diazines Inspired by a Classic Amination Reaction

(2013) P. S. Fier et al.   SCIENCE

Electrophilic Trifluoromethanesulfanylation of Organometallic Species with Trifluoromethanesulfanamides

(2012) François Baert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ortho-Trifluoromethylation of Functionalized Aromatic Triazenes

(2012) Andreas Hafner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Air-Stable Copper Reagent for Nucleophilic Trifluoromethylthiolation of Aryl Halides

(2012) Zhiqiang Weng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Oxidative Trifluoromethylthiolation of Aryl Boronic Acids with TMSCF3 and Elemental Sulfur

(2012) Chao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Developments on the Trifluoromethylation of (Hetero)Arenes

(2012) Xiao-Feng Wu et al.   Chemistry-An Asian Journal

Progress in Copper-Mediated Formation of Trifluoromethylated Arenes

(2012) Tianfei Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct trifluoro-methoxylation of aromatics with perfluoro-methyl-hypofluorite

(2012) Francesco Venturini et al.   JOURNAL OF FLUORINE CHEMISTRY

Practical and innate carbon–hydrogen functionalization of heterocycles

(2012) Yuta Fujiwara et al.   NATURE

Taming of Fluoroform: Direct Nucleophilic Trifluoromethylation of Si, B, S, and C Centers

(2012) G. K. S. Prakash et al.   SCIENCE

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Direct Cupration of Fluoroform

(2011) Alessandro Zanardi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethoxylation of Aryl Stannanes and Arylboronic Acids

(2011) Chenghong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Synthesis of Aryl Trifluoromethyl Sulfides at Room Temperature

(2011) Cheng-Pan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Silver-Mediated Trifluoromethylation of Arenes Using TMSCF3

(2011) Yingda Ye et al.   ORGANIC LETTERS

A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

(2011) E. Lee et al.   SCIENCE

Copper-Mediated Aerobic Oxidative Trifluoromethylation of Terminal Alkynes with Me3SiCF3

(2010) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryl−CF3Bond-Forming Reductive Elimination from Palladium(IV)

(2010) Nicholas D. Ball et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzedortho-Trifluoromethylation of Arenes Using TFA as a Promoter

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids

(2010) Lingling Chu et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

The Organometallic Fluorine Chemistry of Palladium and Rhodium: Studies toward Aromatic Fluorination

(2009) Vladimir V. Grushin   ACCOUNTS OF CHEMICAL RESEARCH

Aromatic trifluoromethylation catalytic in copper

(2009) Masahiro Oishi et al.   CHEMICAL COMMUNICATIONS

New trends in the chemistry of α-fluorinated ethers, thioethers, amines and phosphines

(2009) Baptiste Manteau et al.   JOURNAL OF FLUORINE CHEMISTRY

Formation of ArF from LPdAr(F): Catalytic Conversion of Aryl Triflates to Aryl Fluorides

(2009) D. A. Watson et al.   SCIENCE

Trifluoromethyl ethers – synthesis and properties of an unusual substituent

(2008) Frédéric R Leroux et al.   Beilstein Journal of Organic Chemistry

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Reactivity of a 10-I-3 Hypervalent Iodine Trifluoromethylation Reagent With Phenols

(2008) Kyrill Stanek et al.   JOURNAL OF ORGANIC CHEMISTRY

Active Trifluoromethylating Agents from Well-Defined Copper(I)−CF3Complexes

(2008) Galyna G. Dubinina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

Versatile application of trifluoromethyl triflate

(2007) Alexander A. Kolomeitsev et al.   TETRAHEDRON LETTERS