Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

Title
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Authors
Keywords
-
Journal
MOLECULAR CANCER THERAPEUTICS
Volume 16, Issue 9, Pages 1831-1842
Publisher
American Association for Cancer Research (AACR)
Online
2017-06-16
DOI
10.1158/1535-7163.mct-17-0018

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