Regio- and Stereoselective Alkylboration of Endocyclic Olefins Enabled by Nickel Catalysis

Mechanism-Based Design of an Amide-Directed Ni-Catalyzed Arylboration of Cyclopentene Derivatives

(2021) Alison L. Lambright et al.   ORGANIC LETTERS

Iridium-catalyzed Z-retentive asymmetric allylic substitution reactions

(2021) Ru Jiang et al.   SCIENCE

The Asymmetric Synthesis of Amines via Nickel-Catalyzed Enantioconvergent Substitution Reactions

(2021) Ze-Peng Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photochemical C–H Activation Enables Nickel-Catalyzed Olefin Dicarbofunctionalization

(2021) Mark W. Campbell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prins cyclization-mediated stereoselective synthesis of tetrahydropyrans and dihydropyrans: an inspection of twenty years

(2021) Asha Budakoti et al.   Beilstein Journal of Organic Chemistry

Enantioselective Allylation of Alkenyl Boronates Promotes a 1,2-Metalate Rearrangement with 1,3-Diastereocontrol

(2021) Colton R. Davis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis

(2021) Jiacheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NiH-Catalyzed Migratory Defluorinative Olefin Cross-Coupling: Trifluoromethyl-Substituted Alkenes as Acceptor Olefins to Form gem -Difluoroalkenes

(2020) Fenglin Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium(I)-catalyzed α-C(sp3)–H Alkylation of Saturated Azacycles

(2020) Pritha Verma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in Nickel-Catalyzed Three-Component Difunctionalization of Unactivated Alkenes

(2020) Hai-Yong Tu et al.   SYNTHESIS-STUTTGART

On the Nature of C(sp3)–C(sp2) Bond Formation in Nickel-Catalyzed Tertiary Radical Cross-Couplings: A Case Study of Ni/Photoredox Catalytic Cross-Coupling of Alkyl Radicals and Aryl Halides

(2020) Mingbin Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Chemodivergent 1,1-Difunctionalization of Unactivated α-Olefins with Alkynyl Electrophiles and B2pin2

(2020) Yangyang Li et al.   ACS Catalysis

trans‐Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides via Nickel Catalysis

(2020) Chang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Electrophile Coupling of Unactivated Alkyl Chlorides

(2020) Holt A. Sakai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Medium-Sized Heterocycles by Transition-Metal-Catalyzed Intramolecular Cyclization

(2020) Mickael Choury et al.   MOLECULES

Biocatalytic and Chemo-Enzymatic Approaches for the Synthesis of Heterocycles

(2020) Daniele Castagnolo et al.   SYNTHESIS-STUTTGART

Nickel-Catalyzed Dicarbofunctionalization of Alkenes

(2020) Xiaoxu Qi et al.   ACS Catalysis

Recent advances in nickel-catalyzed reductive hydroalkylation and hydroarylation of electronically unbiased alkenes

(2020) Xiao-Xu Wang et al.   Science China-Chemistry

Catalyst-controlled enantioselective 1,1-arylboration of unactivated olefins

(2020) Wang Wang et al.   Nature Catalysis

Enantioselective Intermolecular Heck and Reductive Heck Reactions of Aryl Triflates, Mesylates, and Tosylates Catalyzed by Nickel

(2020) Xiaolei Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three‐Component Alkene Difunctionalization via Direct and Selective Activation of Aliphatic C‐H Bonds

(2020) Sheng Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Three‐Component Coupling of Heteroarenes, Cycloalkenes and Propargylic Acetates

(2020) Shenghan Teng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactivity and Selectivity Controlling Factors in the Pd/Dialkylbiarylphosphine-Catalyzed C–C Cleavage/Cross-Coupling of an N-Fused Bicyclo α-Hydroxy-β-Lactam

(2020) Li-Ping Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioconvergent Cross−Couplings of Alkyl Electrophiles: The Catalytic Asymmetric Synthesis of Organosilanes

(2019) Gregory C Fu   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Characterization of (Xantphos)Ni(I)-Mediated Alkyl Bromide Activation: Oxidative Addition, Electron Transfer, or Halogen-Atom Abstraction

(2019) Justin B. Diccianni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative C H alkynylation of 3,6-dihydro-2H-pyrans

(2019) Ran Zhao et al.   CHINESE CHEMICAL LETTERS

Migratory Arylboration of Unactivated Alkenes Enabled by Nickel Catalysis

(2019) Wang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Asymmetric Reductive Diarylation of Vinylarenes

(2019) David Anthony et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed 1,1-Alkylboration of Electronically Unbiased Terminal Alkenes

(2019) Yangyang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron-Substituted Quaternary Carbons and Regiodivergent Reactions

(2019) Liang-An Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemo-, Regio-, Diastereo-, and Enantioselective Palladium Allylic Alkylation of 1,3-Dioxaboroles as Synthetic Equivalents of α-Hydroxyketones

(2019) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tackling Remote sp 3 C−H Functionalization via Ni‐Catalyzed “chain‐walking” Reactions

(2019) Daniel Janssen‐Müller et al.   ISRAEL JOURNAL OF CHEMISTRY

Modular Dual-Tasked C–H Methylation via the Catellani Strategy

(2019) Qianwen Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Palladium-Catalyzed 1,3-Arylboration of Unconjugated Dienes for Expedient Synthesis of 1,3-Disubstituted Cyclohexanes

(2019) Hailiang Pang et al.   ACS Catalysis

Enantioselective Radical Addition/Cross-Coupling of Organozinc Reagents, Alkyl Iodides, and Alkenyl Boron Reagents

(2019) Matteo Chierchia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Controlled Regiodivergent Hydroalkylation of Pyrrolines

(2019) Deyun Qian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anodic Oxidation for the Stereoselective Synthesis of Heterocycles

(2019) Kosuke Yamamoto et al.   ACCOUNTS OF CHEMICAL RESEARCH

Difunctionalization of Alkenes Involving Metal Migration

(2019) Yuqiang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Wacker-Type Oxyallenylation and Azaallenylation of Cyclic Alkenes

(2019) Shenghan Teng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal-Catalyzed Dicarbofunctionalization of Unactivated Olefins

(2018) Roshan K. Dhungana et al.   CHEMICAL RECORD

Palladium-Catalyzed Enantioselective Relay Heck Arylation of Enelactams: Accessing α,β-Unsaturated δ-Lactams

(2018) Qianjia Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Borylative Cyclization of 1,6-Dienes: Synthesis of Boron-Substituted Six-Membered Heterocycles and Carbocycles

(2018) Jing Qi et al.   ORGANIC LETTERS

Enantioselective Copper-Catalyzed Methylboration of Alkenes

(2018) Bin Chen et al.   ORGANIC LETTERS

Directed nickel-catalyzed 1,2-dialkylation of alkenyl carbonyl compounds

(2018) Joseph Derosa et al.   Chemical Science

Methyl-containing pharmaceuticals: Methylation in drug design

(2018) Shaoyi Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Site-Selective Ni-Catalyzed Reductive Coupling of α-Haloboranes with Unactivated Olefins

(2018) Shang-Zheng Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenyl Arenes

(2018) Allison M. Bergmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution in Rhodium-Catalyzed Asymmetric Arylation of Phospholene Oxides

(2017) Kelvin Meng-Hui Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Remote Migratory Cross-Electrophile Coupling and Olefin Hydroarylation Reactions Enabled by in Situ Generation of NiH

(2017) Fenglin Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct α-C–H bond functionalization of unprotected cyclic amines

(2017) Weijie Chen et al.   Nature Chemistry

Asymmetric [3+3] Cycloaddition for Heterocycle Synthesis

(2017) Michael Doyle et al.   SYNLETT

The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes

(2017) Richard T. Thornbury et al.   Chemical Science

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes

(2017) Gregory C. Fu   ACS Central Science

The Enantioselective Total Synthesis of Exochomine

(2016) Alison X. Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Palladium-Catalyzed Oxidative β,β-Fluoroarylation of α,β-Unsaturated Carbonyl Derivatives

(2016) Javier Miró et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective Intermolecular Carboetherification of Dihydrofurans

(2016) Gustavo M. Borrajo-Calleja et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development and Analysis of a Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Acrylates Enabled by Chiral Anion Phase Transfer

(2016) Eiji Yamamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalysed transannular C–H functionalization of alicyclic amines

(2016) Joseph J. Topczewski et al.   NATURE

Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides

(2016) Craig P. Johnston et al.   NATURE

Direct Access to Furoindolines by Palladium-Catalyzed Intermolecular Carboamination

(2016) Vincent Bizet et al.   ACS Catalysis

An Improved System for the Aqueous Lipshutz-Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles

(2015) Vasudev R. Bhonde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective sp3 C–H alkylation of γ-butyrolactam by a chiral Ir(i) catalyst for the synthesis of 4-substituted γ-amino acids

(2015) Yu-ki Tahara et al.   CHEMICAL COMMUNICATIONS

Progress of Mitsunobu Reaction in Construction of Chemical Bonds

(2015) Xiaolong Wang et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Asymmetric Arylation of Allyl Sulfones under the Conditions of Isomerization into Alkenyl Sulfones

(2015) Kelvin Meng-Hui Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Enantioselective 1,1-Fluoroarylation of Aminoalkenes

(2015) Ying He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Controlled α- and β-Arylation of Acyclic N-Boc Amines

(2014) Anthony Millet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst-Directed Diastereo- and Site-Selectivity in Successive Nucleophilic and Electrophilic Allylations of Chiral 1,3-Diols: Protecting-Group-Free Synthesis of Substituted Pyrans

(2014) Inji Shin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase

(2014) Jinghan Gui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Enantiospecific sp2–sp3 coupling of secondary and tertiary boronic esters

(2014) Amadeu Bonet et al.   Nature Chemistry

Ruthenium(II)-Catalyzed C(sp3)–H α-Alkylation of Pyrrolidines

(2014) Marvin Schinkel et al.   ORGANIC LETTERS

Unique Regioselectivity in the C(sp3)–H α-Alkylation of Amines: The Benzoxazole Moiety as a Removable Directing Group

(2014) Günther Lahm et al.   ORGANIC LETTERS

Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein–Protein Interaction

(2014) Leifeng Cheng et al.   ACS Medicinal Chemistry Letters

Two- and Three-dimensional Rings in Drugs

(2013) Matteo Aldeghi et al.   Chemical Biology & Drug Design

Rhodium-Catalyzed Asymmetric Hydroarylation of 3-Pyrrolines Giving 3-Arylpyrrolidines: Protonation as a Key Step

(2013) Chau Ming So et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism and Selectivity in Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides

(2013) Soumik Biswas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

[3+2] Cycloaddition of Aziridines and Alkenes Catalyzed by a Cationic Manganese Porphyrin

(2013) Takuya Kurahashi et al.   SYNLETT

Ligand-controlled β-selective C(sp3)–H arylation of N-Boc-piperidines

(2013) Anthony Millet et al.   Chemical Science

The Methylation Effect in Medicinal Chemistry

(2011) Eliezer J. Barreiro et al.   CHEMICAL REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Highly Diastereoselective Arylations of Substituted Piperidines

(2011) Stephanie Seel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Oxidative Arylhalogenation of Alkenes: Synthetic Scope and Mechanistic Insights

(2010) Dipannita Kalyani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitsunobu and Related Reactions: Advances and Applications

(2009) K. C. Kumara Swamy et al.   CHEMICAL REVIEWS

Stereocontrolled synthesis of orthogonally protected 2-substituted 4-aminopiperidines

(2009) Ramón Badorrey et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Oxidatively Intercepting Heck Intermediates:  Pd-Catalyzed 1,2- and 1,1-Arylhalogenation of Alkenes

(2008) Dipannita Kalyani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2-Arylpiperidines by Palladium Couplings of Aryl Bromides with Organozinc Species Derived from Deprotonation ofN-Boc-Piperidine

(2008) Iain Coldham et al.   ORGANIC LETTERS