Enantioselective Three‐Component Coupling of Heteroarenes, Cycloalkenes and Propargylic Acetates

N-Heterocyclic Carbene Complexes in C–H Activation Reactions

(2020) Qun Zhao et al.   CHEMICAL REVIEWS

Nickel-catalysed anti-Markovnikov hydroarylation of unactivated alkenes with unactivated arenes facilitated by non-covalent interactions

(2020) Noam I. Saper et al.   Nature Chemistry

trans‐Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides via Nickel Catalysis

(2020) Chang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bulky Chiral N-Heterocyclic Carbene Nickel Catalyst Enables Enantioselective C-H Functionalizations of Indoles and Pyrroles

(2019) Johannes Diesel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overview of Recent Strategic Advances in Medicinal Chemistry

(2019) Gaochan Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modular, stereocontrolled Cβ–H/Cα–C activation of alkyl carboxylic acids

(2019) Ming Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nickel/NHC-Catalyzed Asymmetric C-H Alkylation of Fluoroarenes with Alkenes: Synthesis of Enantioenriched Fluorotetralins

(2019) Yuan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Amide-Directed Enantioselective Carboboration of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand

(2019) Zibo Bai et al.   ACS Catalysis

Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes

(2019) Zhonglei Wang   MOLECULES

Asymmetric Wacker-Type Oxyallenylation and Azaallenylation of Cyclic Alkenes

(2019) Shenghan Teng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of Selectivity in Palladium(II)-Catalyzed Oxidative Transformations of Allenes

(2018) Bin Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Ni–Al Bimetallic Catalyzed exo-Selective C–H Cyclization of Imidazoles with Alkenes

(2018) Yin-Xia Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand

(2018) Hao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes

(2018) Gregory Beutner et al.   ORGANIC LETTERS

Fickle Reactivity of Allenes in Transition-Metal-Catalyzed C−H Functionalizations

(2018) Rajagopal Santhoshkumar et al.   Asian Journal of Organic Chemistry

Beyond Friedel and Crafts: Innate Alkylation of C-H Bonds in Arenes

(2018) Gwilherm Evano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Beyond Friedel and Crafts: Directed Alkylation of C-H Bonds in Arenes

(2018) Gwilherm Evano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Aluminum-Free Alkene Hydroarylations through C−H Activation by a Chiral Nickel/JoSPOphos Manifold

(2018) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3d Transition Metals for C–H Activation

(2018) Parthasarathy Gandeepan et al.   CHEMICAL REVIEWS

Very Important Publication: Iridium-Catalyzed Intramolecular Enantioselective CH Alkylation at the C-2 Position ofN-Alkenylindoles

(2015) Takanori Shibata et al.   ADVANCED SYNTHESIS & CATALYSIS

Mild Deoxygenation of Aromatic Ketones and Aldehydes over Pd/C Using Polymethylhydrosiloxane as the Reducing Agent

(2015) Alexey Volkov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cationic Iridium/S-Me-BIPAM-Catalyzed Direct Asymmetric Intermolecular Hydroarylation of Bicycloalkenes

(2015) Tomohiko Shirai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective Domino Heck/Intermolecular C–H Bond Functionalization: Development and Application to the Synthesis of (+)-Esermethole

(2015) Wangqing Kong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Dehydrogenative Heck Arylations of Trisubstituted Alkenes with Indoles to Construct Quaternary Stereocenters

(2015) Chun Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-Markovnikov Hydroheteroarylation of Unactivated Alkenes with Indoles, Pyrroles, Benzofurans, and Furans Catalyzed by a Nickel–N-Heterocyclic Carbene System

(2015) York Schramm et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Cyclization Reactions of Allenes in the Presence of Unsaturated Carbon–Carbon Bonds

(2014) Juntao Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ruthenium-Porphyrin-Catalyzed Diastereoselective Intramolecular Alkyl Carbene Insertion into CH Bonds of Alkyl Diazomethanes Generated In Situ fromN-Tosylhydrazones

(2014) Annapureddy Rajasekar Reddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Progress in allene chemistry

(2014) Benito Alcaide et al.   CHEMICAL SOCIETY REVIEWS

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Congested C–C Bonds by Pd-Catalyzed Enantioselective Allyl–Allyl Cross-Coupling, a Mechanism-Guided Solution

(2014) Michael J. Ardolino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Enantioselective Directed C–H Alkylation of Indole with Styrenes

(2014) Pin-Sheng Lee et al.   ORGANIC LETTERS

Regio- and Stereospecific Synthesis of C-3 Functionalized Proline Derivatives by Palladium Catalyzed Directed C(sp3)–H Arylation

(2014) Dominic P. Affron et al.   ORGANIC LETTERS

Two- and Three-dimensional Rings in Drugs

(2013) Matteo Aldeghi et al.   Chemical Biology & Drug Design

Iridium-Catalyzed Intermolecular Asymmetric Hydroheteroarylation of Bicycloalkenes

(2013) Christo S. Sevov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allenes in Catalytic Asymmetric Synthesis and Natural Product Syntheses

(2012) Shichao Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine Is an Organocatalyst for the Reductive Ozonolysis of Alkenes

(2012) Rachel Willand-Charnley et al.   ORGANIC LETTERS

Escape from Flatland 2: complexity and promiscuity

(2012) Frank Lovering   MedChemComm

Organocatalyzed Asymmetric Friedel-Crafts Reactions

(2010) Vincent Terrasson et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Gold-Catalyzed Allylic Alkylation of Indoles with Alcohols: An Efficient Route to Functionalized Tetrahydrocarbazoles

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of Indoles in a New Dimension

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid catalyzed Friedel–Crafts alkylation reactions

(2009) Shu-Li You et al.   CHEMICAL SOCIETY REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Highly Strained Planar-Chiral Platinacycle for Catalytic Activation of Internal Olefins in the Friedel-Crafts Alkylation of Indoles

(2008) Haoxi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Friedel−Crafts Alkylation ReactionsCopper Showed the Way

(2008) Thomas B. Poulsen et al.   CHEMICAL REVIEWS

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE