The immune system's role in sepsis progression, resolution, and long-term outcome

Reflexes in Immunity

(2016) Kevin J. Tracey   CELL

Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages

(2016) Ilana Gabanyi et al.   CELL

Endothelial and Microcirculatory Function and Dysfunction in Sepsis

(2016) James F. Colbert et al.   CLINICS IN CHEST MEDICINE

Toward a Nuanced Understanding of the Role of Infection in Readmissions After Sepsis*

(2016) Hallie C. Prescott   CRITICAL CARE MEDICINE

Association Between Index Hospitalization and Hospital Readmission in Sepsis Survivors*

(2016) Alexander Sun et al.   CRITICAL CARE MEDICINE

Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency

(2016) Asuka Terashima et al.   IMMUNITY

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

(2016) Lonneke A. van Vught et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sepsis-induced immune dysfunction: can immune therapies reduce mortality?

(2016) Matthew J. Delano et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil extracellular traps — the dark side of neutrophils

(2016) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

(2016) Shih-Chin Cheng et al.   NATURE IMMUNOLOGY

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

(2016) Frieda A. Koopman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What Is the Evidence for Harm of Neuromuscular Blockade and Corticosteroid Use in the Intensive Care Unit?

(2016) Djillali Annane   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

The Endothelium in Sepsis

(2016) Can Ince et al.   SHOCK

Reduced Immunocompetent B Cells and Increased Secondary Infection in Elderly Patients With Severe Sepsis

(2016) Kodai Suzuki et al.   SHOCK

Implementation of adaptive methods in early-phase clinical trials

(2016) Gina R. Petroni et al.   STATISTICS IN MEDICINE

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

(2016) Emma E Davenport et al.   Lancet Respiratory Medicine

Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis

(2016) Paula Giselle Czaikoski et al.   PLoS One

Hospitalization Type and Subsequent Severe Sepsis

(2015) Hallie C. Prescott et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Up-regulation of Programmed Cell Death 1 Ligand 1 on Neutrophils May Be Involved in Sepsis-induced Immunosuppression

(2015) Jia-Feng Wang et al.   ANESTHESIOLOGY

Rehospitalizations Following Sepsis

(2015) Dong W. Chang et al.   CRITICAL CARE MEDICINE

Frequency, Cost, and Risk Factors of Readmissions Among Severe Sepsis Survivors*

(2015) Andrew J. Goodwin et al.   CRITICAL CARE MEDICINE

The Epidemiology of Chronic Critical Illness in the United States*

(2015) Jeremy M. Kahn et al.   CRITICAL CARE MEDICINE

Sepsis-induced immune alterations monitoring by flow cytometry as a promising tool for individualized therapy

(2015) Guillaume Monneret et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Readmission Diagnoses After Hospitalization for Severe Sepsis and Other Acute Medical Conditions

(2015) Hallie C. Prescott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

STAT5 phosphorylation in T cell subsets from septic patients in response to recombinant human interleukin-7: a pilot study

(2015) Julie Demaret et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Review of GM-CSF Therapy in Sepsis

(2015) Brittany Mathias et al.   MEDICINE

Complement in therapy and disease

(2015) Joost P.M. Melis et al.   MOLECULAR IMMUNOLOGY

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

Evolutionary insights into host–pathogen interactions from mammalian sequence data

(2015) Manuela Sironi et al.   NATURE REVIEWS GENETICS

Resolvin Infectious Inflammation by Targeting the Host Response

(2015) Craig R. Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systemic Inflammatory Response Syndrome Criteria in Defining Severe Sepsis

(2015) Kirsi-Maija Kaukonen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Getting sepsis therapy right

(2015) R. S. Hotchkiss et al.   SCIENCE

Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis

(2015) G. F. Weber et al.   SCIENCE

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Macrophage-Lineage Cells Negatively Regulate the Hematopoietic Stem Cell Pool in Response to Interferon Gamma at Steady State and During Infection

(2015) Amanda McCabe et al.   STEM CELLS

CD1d- and MR1-Restricted T Cells in Sepsis

(2015) Peter A. Szabo et al.   Frontiers in Immunology

Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness

(2015) Carmen Mikacenic et al.   PLoS One

Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin  3 1-dependent

(2014) Y. V. Lerman et al.   BLOOD

Host Immune Response to Infection and Cancer: Unexpected Commonalities

(2014) Romina S. Goldszmid et al.   Cell Host & Microbe

Natural Killer Cells in Sepsis

(2014) Evangelos J. Giamarellos-Bourboulis   CRITICAL CARE MEDICINE

Depletion of Natural Killer Cells Increases Mice Susceptibility in a Pseudomonas aeruginosa Pneumonia Model*

(2014) Alexis Broquet et al.   CRITICAL CARE MEDICINE

The Next Generation of Sepsis Clinical Trial Designs

(2014) Steven M. Opal et al.   CRITICAL CARE MEDICINE

Exploring the Scope of Post–Intensive Care Syndrome Therapy and Care

(2014) Doug Elliott et al.   CRITICAL CARE MEDICINE

A Better Understanding of Why Murine Models of Trauma Do Not Recapitulate the Human Syndrome*

(2014) Lori F. Gentile et al.   CRITICAL CARE MEDICINE

Restoring the balance: immunotherapeutic combinations for autoimmune disease

(2014) D. E. Smilek et al.   Disease Models & Mechanisms

Epigenetic coordination of acute systemic inflammation: potential therapeutic targets

(2014) Vidula Vachharajani et al.   Expert Review of Clinical Immunology

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic Cells Modulate Lung Response to Pseudomonas aeruginosa in a Murine Model of Sepsis-Induced Immune Dysfunction

(2014) F. Pene et al.   JOURNAL OF IMMUNOLOGY

The Common  -Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Induce the Expression of Programmed Death-1 and Its Ligands

(2014) A. L. Kinter et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Critical Role for C5aRs in the Development of Septic Lymphopenia in Mice

(2014) Jamison J. Grailer et al.   JOURNAL OF IMMUNOLOGY

Microbe-Specific Unconventional T Cells Induce Human Neutrophil Differentiation into Antigen Cross-Presenting Cells

(2014) Martin S. Davey et al.   JOURNAL OF IMMUNOLOGY

Persistent Neutrophil Dysfunction and Suppression of Acute Lung Injury in Mice following Cecal Ligation and Puncture Sepsis

(2014) Jamison J. Grailer et al.   Journal of Innate Immunity

Post-infectious immune suppression: A new paradigm of severe infections

(2014) D. Grimaldi et al.   MEDECINE ET MALADIES INFECTIEUSES

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Parallels between Cancer and Infectious Disease

(2014) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reactivation of Multiple Viruses in Patients with Sepsis

(2014) Andrew H. Walton et al.   PLoS One

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Persistent Lymphopenia After Diagnosis of Sepsis Predicts Mortality

(2014) Anne M. Drewry et al.   SHOCK

The new normal: immunomodulatory agents against sepsis immune suppression

(2014) Noelle A. Hutchins et al.   TRENDS IN MOLECULAR MEDICINE

Why have clinical trials in sepsis failed?

(2014) John C. Marshall   TRENDS IN MOLECULAR MEDICINE

The Surviving Sepsis Campaign: past, present and future

(2014) Christa A. Schorr et al.   TRENDS IN MOLECULAR MEDICINE

Immune Effects of Interferon Gamma in Persistent Staphylococcal Sepsis

(2013) Marek Nalos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Warburg effect then and now: From cancer to inflammatory diseases

(2013) Eva M. Palsson-McDermott et al.   BIOESSAYS

Association of γδ T Cells with Disease Severity and Mortality in Septic Patients

(2013) Juan C. Andreu-Ballester et al.   Clinical and Vaccine Immunology

Long-term consequences of severe infections

(2013) L. Leibovici   CLINICAL MICROBIOLOGY AND INFECTION

Benchmarking the Incidence and Mortality of Severe Sepsis in the United States*

(2013) David F. Gaieski et al.   CRITICAL CARE MEDICINE

Calcium Supplementation During Sepsis Exacerbates Organ Failure and Mortality via Calcium/Calmodulin-Dependent Protein Kinase Kinase Signaling

(2013) Richard D. Collage et al.   CRITICAL CARE MEDICINE

Development of a Genomic Metric That Can Be Rapidly Used to Predict Clinical Outcome in Severely Injured Trauma Patients*

(2013) Alex G. Cuenca et al.   CRITICAL CARE MEDICINE

Intestinal innate immune cells in gut homeostasis and immunosurveillance

(2013) Elena Tomasello et al.   IMMUNOLOGY AND CELL BIOLOGY

Associations of T helper 1, 2, 17 and regulatory T lymphocytes with mortality in severe sepsis

(2013) Huang-Pin Wu et al.   INFLAMMATION RESEARCH

Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections

(2013) David Grimaldi et al.   INTENSIVE CARE MEDICINE

Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

(2013) H. Unnewehr et al.   JOURNAL OF IMMUNOLOGY

Aged Mice Are Unable To Mount an Effective Myeloid Response to Sepsis

(2013) D. C. Nacionales et al.   JOURNAL OF IMMUNOLOGY

Granulocyte–macrophage colony-stimulating factor: not just another haematopoietic growth factor

(2013) Alejandro Francisco-Cruz et al.   MEDICAL ONCOLOGY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Reduced frequency of CD56dim CD16pos natural killer cells in pediatric systemic inflammatory response syndrome/sepsis patients

(2013) E. Scott Halstead et al.   PEDIATRIC RESEARCH

Endothelium Dependent Vasomotion and In Vitro Markers of Endothelial Repair in Patients with Severe Sepsis: An Observational Study

(2013) Sabrina H. van Ierssel et al.   PLoS One

Histones-Mediated Lymphocyte Apoptosis during Sepsis Is Dependent on p38 Phosphorylation and Mitochondrial Permeability Transition

(2013) Zhan-Guo Liu et al.   PLoS One

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

(2013) Sanne P. Smeekens et al.   Nature Communications

The role of mitochondrial dysfunction in sepsis-induced multi-organ failure

(2013) Mervyn Singer   Virulence

Epidemiology of severe sepsis

(2013) Florian B Mayr et al.   Virulence

A Historical Perspective on Sepsis

(2012) Peter A. Ward et al.   AMERICAN JOURNAL OF PATHOLOGY

Long-Term Propranolol Use in Severely Burned Pediatric Patients

(2012) David N. Herndon et al.   ANNALS OF SURGERY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

(2012) M.-A. Perales et al.   BLOOD

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

Ventilator-Associated Pneumonia Is Characterized by Excessive Release of Neutrophil Proteases in the Lung

(2012) Thomas S. Wilkinson et al.   CHEST

Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study

(2012) Y. Lévy et al.   CLINICAL INFECTIOUS DISEASES

A comparison of critical care research funding and the financial burden of critical illness in the United States*

(2012) Craig M. Coopersmith et al.   CRITICAL CARE MEDICINE

Interferon-γ production by natural killer cells and cytomegalovirus in critically ill patients*

(2012) Laurent Chiche et al.   CRITICAL CARE MEDICINE

The function of neutrophils in sepsis

(2012) Melissa A. Kovach et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes

(2012) Greg S Martin   Expert Review of Anti-Infective Therapy

Regulation of mitochondrial function and energetics by reactive nitrogen oxides

(2012) Filip J Larsen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cytochrome c oxidase dysfunction in oxidative stress

(2012) Satish Srinivasan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Myeloid-Derived Suppressor Cells Evolve during Sepsis and Can Enhance or Attenuate the Systemic Inflammatory Response

(2012) Laura Brudecki et al.   INFECTION AND IMMUNITY

Persistent inflammation and immunosuppression

(2012) Lori F. Gentile et al.   Journal of Trauma and Acute Care Surgery

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate Response Activator B Cells Protect Against Microbial Sepsis

(2012) P. J. Rauch et al.   SCIENCE

Generation of Nitric Oxide and Reactive Oxygen Species by Neutrophils and Monocytes From Septic Patients and Association With Outcomes

(2012) Sidnéia Sousa Santos et al.   SHOCK

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

Subsequent Infections in Survivors of Sepsis

(2012) Tisha Wang et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Signaling Mechanism of Poly(ADP-Ribose) Polymerase-1 (PARP-1) in Inflammatory Diseases

(2011) Xueqing Ba et al.   AMERICAN JOURNAL OF PATHOLOGY

C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients

(2011) A. C. Morris et al.   BLOOD

Risk factors for recurrence and death after bacteraemia: a population-based study

(2011) U.S. Jensen et al.   CLINICAL MICROBIOLOGY AND INFECTION

A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury*

(2011) Robert Paine et al.   CRITICAL CARE MEDICINE

Improving long-term outcomes after discharge from intensive care unit

(2011) Dale M. Needham et al.   CRITICAL CARE MEDICINE

Epigenetic regulation of immune cell functions during post-septic immunosuppression

(2011) William F. Carson et al.   Epigenetics

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

(2011) D. Grimaldi et al.   INTENSIVE CARE MEDICINE

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

B cells enhance early innate immune responses during bacterial sepsis

(2011) Kindra M. Kelly-Scumpia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling

(2011) M. J. Delano et al.   JOURNAL OF IMMUNOLOGY

Unknown

(2011) Alex Cuenca et al.   MOLECULAR MEDICINE

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

(2011) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth

(2010) K. A. Cavassani et al.   BLOOD

Beta-block the septic heart

(2010) Alain Rudiger   CRITICAL CARE MEDICINE

Long-term mortality and quality of life in sepsis: A systematic review*

(2010) Bradford D. Winters et al.   CRITICAL CARE MEDICINE

Burns: where are we standing with propranolol, oxandrolone, recombinant human growth hormone, and the new incretin analogs?

(2010) Gerd G Gauglitz et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Temporal trends of circulating nitric oxide and pro-inflammatory cytokine responses ex vivo in intra-abdominal sepsis: results from a cohort study

(2010) Miriam Ojeda Ojeda et al.   INFLAMMATION RESEARCH

Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome

(2010) Mark W. Hall et al.   INTENSIVE CARE MEDICINE

Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock

(2010) Caroline Landelle et al.   INTENSIVE CARE MEDICINE

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10

(2010) Kindra M. Kelly-Scumpia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modulation of Dendritic Cell Differentiation in the Bone Marrow Mediates Sustained Immunosuppression after Polymicrobial Sepsis

(2010) E. Pastille et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling

(2010) Philip O. Scumpia et al.   JOURNAL OF IMMUNOLOGY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Sepsis Induces Early Alterations in Innate Immunity That Impact Mortality to Secondary Infection

(2010) M. J. Delano et al.   JOURNAL OF IMMUNOLOGY

IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis

(2010) J. Unsinger et al.   JOURNAL OF IMMUNOLOGY

The Harmful Role of C5a on Innate Immunity in Sepsis

(2010) Peter A. Ward   Journal of Innate Immunity

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

(2010) P. Brahmamdam et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effects of cAMP and β-Adrenergic Receptor Antagonists on the Function of Peripheral T Helper Lymphocytes in Patients with Heart Failure

(2010) Xiuqing Tian et al.   NEUROIMMUNOMODULATION

PATHOPHYSIOLOGICAL ROLES OF PEROXYNITRITE IN CIRCULATORY SHOCK

(2010) Csaba Szabó et al.   SHOCK

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

Magic bullets and surrogate biomarkers circa 2009*

(2009) Matthew J. Delano et al.   CRITICAL CARE MEDICINE

A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome

(2009) Anna J. Dare et al.   FREE RADICAL BIOLOGY AND MEDICINE

IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis

(2009) S. Inoue et al.   JOURNAL OF IMMUNOLOGY

Cholinergic control of inflammation

(2009) M. Rosas-Ballina et al.   JOURNAL OF INTERNAL MEDICINE

The sepsis seesaw: tilting toward immunosuppression

(2009) Richard S Hotchkiss et al.   NATURE MEDICINE

Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus

(2009) y.-y. li et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bandit solutions provide unified ethical models for randomized clinical trials and comparative effectiveness research

(2009) William H. Press   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

(2009) J. C. Alves-Filho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Microparticles from Patients with Septic Shock Exert Protective Role in Vascular Function

(2008) Hadj Ahmed Mostefai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inflammatory Markers at Hospital Discharge Predict Subsequent Mortality after Pneumonia and Sepsis

(2008) Sachin Yende et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CD56brightnatural killer (NK) cells: an important NK cell subset

(2008) Aurélie Poli et al.   IMMUNOLOGY

Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients

(2008) Fabienne Venet et al.   INTENSIVE CARE MEDICINE

Reactivation of Cytomegalovirus Infection in Critically Ill Immunocompetent Patients—Reply

(2008) Ajit P. Limaye   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Unknown

(2008) Guillaume Monneret et al.   MOLECULAR MEDICINE

THE PROTECTIVE EFFECT OF THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY AGAINST SEPTIC SHOCK IN RATS

(2008) Xue-Min Song et al.   SHOCK

Adaptive Clinical Trials

(2008) Christopher S Coffey et al.   Drugs in research & development

Could Beta Blockade Improve Outcome After Injury by Modulating Inflammatory Profiles?

(2008) Randall S. Friese et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE