Sepsis-induced immune alterations monitoring by flow cytometry as a promising tool for individualized therapy

Up-regulation of Programmed Cell Death 1 Ligand 1 on Neutrophils May Be Involved in Sepsis-induced Immunosuppression

(2015) Jia-Feng Wang et al.   ANESTHESIOLOGY

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis

(2015) Lee J.L. Markwick et al.   GASTROENTEROLOGY

High circulating CD39+ regulatory T cells predict poor survival for sepsis patients

(2015) Huihuang Huang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Increased regulatory T cells in patients with liver cirrhosis correlated with hyperbilirubinemia and predict bacterial complications

(2015) Chien-Hao Huang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

STAT5 phosphorylation in T cell subsets from septic patients in response to recombinant human interleukin-7: a pilot study

(2015) Julie Demaret et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Severe Lymphopenia Is Associated with Elevated Plasma Interleukin-15 Levels and Increased Mortality During Severe Sepsis

(2015) Kuei-Pin Chung et al.   SHOCK

Patterns of monocyte subpopulations and their surface expression of HLA-DR during adverse events after hematopoietic stem cell transplantation

(2014) Michaela Döring et al.   ANNALS OF HEMATOLOGY

Characterisation of gamma delta (γδ) T cell populations in patients with sepsis

(2014) Helen F. Galley et al.   CELL BIOLOGY INTERNATIONAL

Blockade of the T cell immunoglobulin and mucin domain protein 3 pathway exacerbates sepsis-induced immune deviation and immunosuppression

(2014) Z. Zhao et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Long-Term (10-Year) Mortality of Younger Previously Healthy Patients With Severe Sepsis/Septic Shock Is Worse Than That of Patients With Nonseptic Critical Illness and of the General Population

(2014) Adam Linder et al.   CRITICAL CARE MEDICINE

Circulating Immature Granulocytes With T-Cell Killing Functions Predict Sepsis Deterioration*

(2014) Estelle Guérin et al.   CRITICAL CARE MEDICINE

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Sepsis affects most routine and cell population data (CPD) obtained using the Sysmex XN-2000 blood cell analyzer: neutrophil-related CPD NE-SFL and NE-WY provide useful information for detecting sepsis

(2014) S. H. Park et al.   International Journal of Laboratory Hematology

Flow cytometric evaluation of lymphocyte transformation test based on 5-ethynyl-2′deoxyuridine incorporation as a clinical alternative to tritiated thymidine uptake measurement

(2014) Fanny Poujol et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Decreased Expression of the Fractalkine Receptor CX3CR1 on Circulating Monocytes as New Feature of Sepsis-Induced Immunosuppression

(2014) Alexandre Pachot et al.   JOURNAL OF IMMUNOLOGY

Impact of sepsis on CD4 T cell immunity

(2014) Javier Cabrera-Perez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Postoperative Immunosuppression After Open and Laparoscopic Liver Resection: Assessment of Cellular Immune Function and Monocytic HLA-DR Expression

(2014) Sascha S. Chopra et al.   JSLS-Journal of the Society of Laparoendoscopic Surgeons

Reactivation of Multiple Viruses in Patients with Sepsis

(2014) Andrew H. Walton et al.   PLoS One

Tim-3 Negatively Mediates Natural Killer Cell Function in LPS-Induced Endotoxic Shock

(2014) Hongyan Hou et al.   PLoS One

Fraction of immature granulocytes reflects severity but not mortality in sepsis

(2014) Sang Ook Ha et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Persistent Lymphopenia After Diagnosis of Sepsis Predicts Mortality

(2014) Anne M. Drewry et al.   SHOCK

The new normal: immunomodulatory agents against sepsis immune suppression

(2014) Noelle A. Hutchins et al.   TRENDS IN MOLECULAR MEDICINE

Long-term mortality after community-acquired sepsis: a longitudinal population-based cohort study

(2014) Henry E Wang et al.   BMJ Open

Reduction of Immunocompetent T Cells Followed by Prolonged Lymphopenia in Severe Sepsis in the Elderly*

(2013) Shigeaki Inoue et al.   CRITICAL CARE MEDICINE

Monitoring the immune response in sepsis: a rational approach to administration of immunoadjuvant therapies

(2013) Fabienne Venet et al.   CURRENT OPINION IN IMMUNOLOGY

Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections

(2013) David Grimaldi et al.   INTENSIVE CARE MEDICINE

Increased MerTK expression in circulating innate immune cells of patients with septic shock

(2013) Caroline Guignant et al.   INTENSIVE CARE MEDICINE

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

IL-7 Modulates In Vitro and In Vivo Human Memory T Regulatory Cell Functions through the CD39/ATP Axis

(2013) M. Younas et al.   JOURNAL OF IMMUNOLOGY

Sepsis definitions: time for change

(2013) Jean-Louis Vincent et al.   LANCET

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Decreased T-Cell Repertoire Diversity in Sepsis

(2012) Fabienne Venet et al.   CRITICAL CARE MEDICINE

Inter-laboratory assessment of flow cytometric monocyte HLA-DR expression in clinical samples

(2012) Julie Demaret et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

NK Cell Tolerance to TLR Agonists Mediated by Regulatory T Cells after Polymicrobial Sepsis

(2012) F. Souza-Fonseca-Guimaraes et al.   JOURNAL OF IMMUNOLOGY

BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction

(2012) N. J. Shubin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TLR3 agonist improves survival to secondary pneumonia in a double injury model

(2012) Christopher G. Davis et al.   JOURNAL OF SURGICAL RESEARCH

Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study

(2012) Mitchell M Levy et al.   LANCET INFECTIOUS DISEASES

Unknown

(2012) Fernando Souza-Fonseca-Guimaraes et al.   MOLECULAR MEDICINE

Phenotype and Functions of Natural Killer Cells in Critically-Ill Septic Patients

(2012) Jean-Marie Forel et al.   PLoS One

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

Subsequent Infections in Survivors of Sepsis

(2012) Tisha Wang et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Cytomegalovirus reactivation in critically ill immunocompetent hosts: A decade of progress and remaining challenges

(2011) Charles H. Cook et al.   ANTIVIRAL RESEARCH

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

(2011) D. Grimaldi et al.   INTENSIVE CARE MEDICINE

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Role of Natural Killer Cells in Sepsis

(2011) Laurent Chiche et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunosuppressive CD14+HLA-DRlow/- monocytes in B-cell non-Hodgkin lymphoma

(2010) Y. Lin et al.   BLOOD

Flow cytometric analysis of peripheral blood dendritic cells in patients with severe sepsis

(2010) Francesca Riccardi et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome

(2010) Mark W. Hall et al.   INTENSIVE CARE MEDICINE

Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock

(2010) Caroline Landelle et al.   INTENSIVE CARE MEDICINE

Critical care and the global burden of critical illness in adults

(2010) Neill KJ Adhikari et al.   LANCET

ICU-acquired immunosuppression and the risk for secondary fungal infections

(2010) Guillaume Monneret et al.   MEDICAL MYCOLOGY

Immunotherapy for Sepsis — A New Approach against an Ancient Foe

(2010) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Percentages of CD4+ T regulatory cells and HLA-DR expressing monocytes in severe intra-abdominal infections

(2010) Fu Qiang et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

EARLY ASSESSMENT OF LEUKOCYTE ALTERATIONS AT DIAGNOSIS OF SEPTIC SHOCK

(2010) Fabienne Venet et al.   SHOCK

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macroscopic Postmortem Findings in 235 Surgical Intensive Care Patients with Sepsis

(2009) Christian Torgersen et al.   ANESTHESIA AND ANALGESIA

Circulating dendritic cells following burn

(2009) N. D’Arpa et al.   BURNS

Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis

(2009) Ferah Genel et al.   JOURNAL OF INFECTION

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Viral infections in the ICU

(2008) Charles-Edouard Luyt et al.   Current Opinion in Critical Care

Nosocomial Infection After Septic Shock Among Intensive Care Unit Patients

(2008) Caroline Landelle et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients

(2008) Fabienne Venet et al.   INTENSIVE CARE MEDICINE

Unknown

(2008) Guillaume Monneret et al.   MOLECULAR MEDICINE