Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats

Emodin-induced autophagic cell death hinders epithelial–mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis

(2021) Wei Liu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Crosstalk between tubular epithelial cells and glomerular endothelial cells in diabetic kidney disease

(2020) Si-Jie Chen et al.   CELL PROLIFERATION

EZH2 deficiency attenuates Treg differentiation in rheumatoid arthritis

(2020) Xin-yue Xiao et al.   JOURNAL OF AUTOIMMUNITY

Vaccarin Regulates Diabetic Chronic Wound Healing through FOXP2/AGGF1 Pathways

(2020) Yixiao Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MiR ‐122‐5p and miR ‐326‐3p promote cadmium‐induced NRK‐52E cell apoptosis by downregulating PLD1

(2020) Wenya Yuan et al.   ENVIRONMENTAL TOXICOLOGY

Icariin Prevents Extracellular Matrix Accumulation and Ameliorates Experimental Diabetic Kidney Disease by Inhibiting Oxidative Stress via GPER Mediated p62-Dependent Keap1 Degradation and Nrf2 Activation

(2020) Kai Wang et al.   Frontiers in Cell and Developmental Biology

Icariin alleviates rheumatoid arthritis via regulating miR-223-3p/NLRP3 signalling axis

(2020) Zhi-Ming Wu et al.   AUTOIMMUNITY

Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss

(2020) Yuki Nakao et al.   Acta Biomaterialia

FX5 as a non-steroidal GR antagonist improved glucose homeostasis in type 2 diabetic mice via GR/HNF4α/miR-122-5p pathway

(2020) Xin Xu et al.   Aging-US

Knockdown of the Long Noncoding RNA LUCAT1 Inhibits High-Glucose-Induced Epithelial-Mesenchymal Transition through the miR-199a-5p–ZEB1 Axis in Human Renal Tubular Epithelial Cells

(2020) Li-Cai Zhang et al.   Biomed Research International

Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

(2020) Shan Liu et al.   Molecular Therapy-Nucleic Acids

MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells

(2019) Yong Liu et al.   MOLECULAR THERAPY

The antifibrotic and anti-inflammatory effects of icariin on the kidney in a unilateral ureteral obstruction mouse model

(2019) Hsin‐An Chen et al.   PHYTOMEDICINE

Overexpression of microRNA-21 mediates Ang II-induced renal fibrosis by activating the TGF-β1/Smad3 pathway via suppressing PPARα

(2019) Huiyan Lv et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

lncRNA MALAT1 mediated high glucose–induced HK-2 cell epithelial-to-mesenchymal transition and injury

(2019) Jun Zhang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

A potential role of the renin-angiotensin-aldosterone system in epithelial-to-mesenchymal transition-induced renal abnormalities: Mechanisms and therapeutic implications

(2019) Pitchai Balakumar et al.   PHARMACOLOGICAL RESEARCH

Icariin‐induced miR‐875‐5p attenuates epithelial‐mesenchymal transition by targeting hedgehog signaling in liver fibrosis

(2019) Lei Ye et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

lncRNA XIST attenuates hypoxia-induced H9c2 cardiomyocyte injury by targeting the miR-122-5p/FOXP2 axis

(2019) Hui Peng et al.   MOLECULAR AND CELLULAR PROBES

Update on Diabetic Nephropathy: Core Curriculum 2018

(2018) Kausik Umanath et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Salidroside protects renal tubular epithelial cells from hypoxia/reoxygenation injury in vitro

(2018) Yan Sun et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease

(2018) Yue Wang et al.   Journal of Translational Medicine

Protective Effect of Znt7 on High Glucose-Induced Epithelial-to-Mesenchymal Transition in Renal Tubular Epithelial Cells

(2018) Xiuli  Zhang et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

Icariin alleviates murine lupus nephritis via inhibiting NF-κB activation pathway and NLRP3 inflammasome

(2018) Bofeng Su et al.   LIFE SCIENCES

MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse

(2018) Longfei Jia et al.   MOLECULAR NEUROBIOLOGY

Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway

(2018) Yan-dan Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

LncRNA ANRIL promotes NLRP3 inflammasome activation in uric acid nephropathy through miR-122-5p/BRCC3 axis

(2018) Jiacai Hu et al.   BIOCHIMIE

miR-30e targets GLIPR-2 to modulate diabetic nephropathy: in vitro and in vivo experiments

(2017) Dong Zhao et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

(2016) Chiara Angiolilli et al.   ANNALS OF THE RHEUMATIC DISEASES

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA

(2015) Sachin S. Hajarnis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-specific gene expression profiles in different kidney cell types are associated with Fabry disease

(2015) YOUN-JEONG SHIN et al.   Molecular Medicine Reports

Protective effect of icariin on kidney in 5/6 nephrectomized rats and its mechanism

(2014) S.R. Liang et al.   GENETICS AND MOLECULAR RESEARCH

Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor β1 and type IV collagen expression in rats

(2011) Min-You Qi et al.   JOURNAL OF ETHNOPHARMACOLOGY