Identification of β‐aminopyrrolidine containing peptides as β‐amyloid aggregation inhibitors for Alzheimer's disease

Current Strategies for Modulating Aβ Aggregation with Multifunctional Agents

(2021) Zhi Du et al.   ACCOUNTS OF CHEMICAL RESEARCH

A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies

(2021) Santosh Kumar Verma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rapid Conversion of Amyloid-Beta 1-40 Oligomers to Mature Fibrils through a Self-Catalytic Bimolecular Process

(2021) Bertrand Morel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regioselective competitive synthesis of 3,5-bis(het) aryl pyrrole-2-carboxylates/carbonitriles vs. β-enaminones from β-thioxoketones

(2021) Kothanahally S. Sharath Kumar et al.   TETRAHEDRON LETTERS

Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies

(2021) Gao-Feng Zha et al.   BIOORGANIC CHEMISTRY

AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment

(2021) Kothanahally S. Sharath Kumar et al.   COORDINATION CHEMISTRY REVIEWS

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

(2020) Luca Ferrari et al.   Nature Communications

The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors

(2020) Ziwen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Catalyst free sequential one‐pot reaction for the synthesis of 3‐indole propanoates/propanoic acid/propanamides as antituberculosis agents

(2020) Narasimhamurthy Rajeev et al.   JOURNAL OF THE CHINESE CHEMICAL SOCIETY

Natural Compounds as Inhibitors of Aβ Peptide Aggregation: Chemical Requirements and Molecular Mechanisms

(2020) Katiuscia Pagano et al.   Frontiers in Neuroscience

Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation

(2020) Rameshwari Verma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies

(2019) Yingying Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of new tetramethylpyrazine based chalcone derivatives as potential anti-Alzheimer agents

(2018) Meng Wang et al.   Chemical Biology & Drug Design

A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression

(2018) Hanumappa Ananda et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Autocyclized and Oxidized Forms of SCR7 Induce Cancer Cell Death by Inhibiting Nonhomologous DNA End joining in a Ligase IV Dependent Manner

(2018) Supriya V. Vartak et al.   FEBS Journal

A new era for understanding amyloid structures and disease

(2018) Matthew G. Iadanza et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

(2017) V. Castelletto et al.   Scientific Reports

Platelet protective efficacy of 3,4,5 trisubstituted isoxazole analogue by inhibiting ROS-mediated apoptosis and platelet aggregation

(2016) Swamy Jagadish et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Induction of apoptosis and downregulation of ERα in DMBA-induced mammary gland tumors in Sprague–Dawley rats by synthetic 3,5-disubstituted isoxazole derivatives

(2016) Hanumappa Ananda et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Regioselective synthesis and biological studies of novel 1-aryl-3, 5-bis (het) aryl pyrazole derivatives as potential antiproliferative agents

(2016) Hanumappa Ananda et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivatives

(2015) Kothanahally S. Sharath Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers

(2014) Tadamasa Arai et al.   CHEMBIOCHEM

A Catalyst-free Green Protocol for the Synthesis of Pyranopyrazoles Using Room Temperature Ionic Liquid Choline Chloride-urea

(2014) Toreshettahally R. Swaroop et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

ZnO: An Ecofriendly, Green Nano-catalyst for the Synthesis of Pyrazole Derivatives under Aqueous Media

(2014) Yarabally R. Girish et al.   JOURNAL OF THE CHINESE CHEMICAL SOCIETY

Synthetic Utility of Propylphosphonic Anhydride–DMSO Media: An Efficient One-pot Three-component Synthesis of 2-Arylquinolines

(2013) Kereyagalahally H. Narasimhamurthy et al.   CHEMISTRY LETTERS

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-Methylated Peptide SEN304 Powerfully Inhibits Aβ(1–42) Toxicity by Perturbing Oligomer Formation

(2012) Hozefa Amijee et al.   BIOCHEMISTRY

T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols

(2012) Kothanahally S. Sharath Kumar et al.   TETRAHEDRON LETTERS

Mutations That Replace Aromatic Side Chains Promote Aggregation of the Alzheimer’s Aβ Peptide

(2011) Anne H. Armstrong et al.   BIOCHEMISTRY

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

(2011) U. B. Pandey et al.   PHARMACOLOGICAL REVIEWS

Orally Administrated Cinnamon Extract Reduces β-Amyloid Oligomerization and Corrects Cognitive Impairment in Alzheimer's Disease Animal Models

(2011) Anat Frydman-Marom et al.   PLoS One

Complete Phenotypic Recovery of an Alzheimer's Disease Model by a Quinone-Tryptophan Hybrid Aggregation Inhibitor

(2010) Roni Scherzer-Attali et al.   PLoS One

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Small molecule inhibitors of Aβ-aggregation and neurotoxicity

(2009) Cheryl A. Hawkes et al.   DRUG DEVELOPMENT RESEARCH

Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

(2008) Koichi Iijima et al.   PLoS One