Chemical Synthesis of Antibody–Hapten Conjugates Capable of Recruiting the Endogenous Antibody to Magnify the Fc Effector Immunity of Antibody for Cancer Immunotherapy

Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

(2021) Sina Bondza et al.   Frontiers in Immunology

Site-Selective Chemoenzymatic Modification on the Core Fucose of an Antibody Enhances Its Fcγ Receptor Affinity and ADCC Activity

(2021) Chao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FDA approves 100th monoclonal antibody product

(2021) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Fc‐binding antibody‐recruiting molecules targeting prostate‐specific membrane antigen: defucosylation of antibody for efficacy improvement

(2020) Koichi Sasaki et al.   CHEMBIOCHEM

Binding mechanisms of therapeutic antibodies to human CD20

(2020) Anand Kumar et al.   SCIENCE

Margetuximab for the treatment of HER2-positive metastatic breast cancer

(2020) Paolo Tarantino et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Detection and quantification of free sulfhydryls in monoclonal antibodies using maleimide labeling and mass spectrometry

(2019) Anna C. Robotham et al.   mAbs

Glycoengineering of Antibodies for Modulating Functions

(2019) Lai-Xi Wang et al.   Annual Review of Biochemistry

Considerations for the Design of Antibody-Based Therapeutics

(2019) Dennis R. Goulet et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Antibody glycoengineering strategies in mammalian cells

(2018) Qiong Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

The CD20-specific engineered toxin antibody MT-3724 exhibits lethal effects against mantle cell lymphoma

(2018) Shengjian Huang et al.   Blood Cancer Journal

Engineering of Fc Fragments with Optimized Physicochemical Properties Implying Improvement of Clinical Potentials for Fc-Based Therapeutics

(2018) Chunpeng Yang et al.   Frontiers in Immunology

Past, Present, and Future of Rituximab—The World’s First Oncology Monoclonal Antibody Therapy

(2018) Timothy M. Pierpont et al.   Frontiers in Oncology

Cellular Cytotoxicity of Next-Generation CD20 Monoclonal Antibodies

(2018) Karl R. VanDerMeid et al.   Cancer Immunology Research

Structure, heterogeneity and developability assessment of therapeutic antibodies

(2018) Yingda Xu et al.   mAbs

Modulating IgG effector function by Fc glycan engineering

(2017) Tiezheng Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Nanobody Activation Immunotherapeutic that Selectively Destroys HER2-Positive Breast Cancer Cells

(2015) Melissa A. Gray et al.   CHEMBIOCHEM

Current ADC Linker Chemistry

(2015) Nareshkumar Jain et al.   PHARMACEUTICAL RESEARCH

Rhamnose Glycoconjugates for the Recruitment of Endogenous Anti-Carbohydrate Antibodies to Tumor Cells

(2014) Rachael T. C. Sheridan et al.   CHEMBIOCHEM

Antibody-Recruiting Molecules: An Emerging Paradigm for Engaging Immune Function in Treating Human Disease

(2012) Patrick J. McEnaney et al.   ACS Chemical Biology

Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals

(2012) Rosa Lapalombella et al.   CANCER CELL

Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions

(2012) Wei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor

(2011) Guozhang Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

l-Rhamnose Antigen: A Promising Alternative to α-Gal for Cancer Immunotherapies

(2010) Wenlan Chen et al.   ACS Chemical Biology

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity

(2010) E. Mossner et al.   BLOOD

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

(2010) Gregory L. Moore et al.   mAbs

Optimization of Fc-mediated effector functions of monoclonal antibodies

(2009) William R Strohl   CURRENT OPINION IN BIOTECHNOLOGY

Profiling Human Serum Antibodies with a Carbohydrate Antigen Microarray

(2009) Oyindasola Oyelaran et al.   JOURNAL OF PROTEOME RESEARCH