Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products

The parasite cytokine mimic Hp‐ TGM potently replicates the regulatory effects of TGF‐β on murine CD4 + T cells

(2021) Madeleine PJ White et al.   IMMUNOLOGY AND CELL BIOLOGY

Induction of stable human FOXP3 + Tregs by a parasite‐derived TGF‐β mimic

(2021) Laura Cook et al.   IMMUNOLOGY AND CELL BIOLOGY

Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity

(2020) John W. McGinty et al.   IMMUNITY

A helminth-derived suppressor of ST2 blocks allergic responses

(2020) Francesco Vacca et al.   eLife

The Intestinal Epithelium at the Forefront of Host–Helminth Interactions

(2020) Gillian Coakley et al.   TRENDS IN PARASITOLOGY

Fasciola hepatica-Derived Molecules as Regulators of the Host Immune Response

(2020) Sinéad Ryan et al.   Frontiers in Immunology

Tuning tuft cells: new ligands and effector functions reveal tissue-specific function

(2020) Tyler E Billipp et al.   CURRENT OPINION IN IMMUNOLOGY

Eicosanoids in tissue repair

(2019) Julia Esser-von Bieren   IMMUNOLOGY AND CELL BIOLOGY

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

(2018) Christoph Schneider et al.   CELL

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

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(2018) Peter Mark Jourdan et al.   LANCET

Epithelial Hes1 maintains gut homeostasis by preventing microbial dysbiosis

(2018) X-K Guo et al.   Mucosal Immunology

Immunity to gastrointestinal nematode infections

(2018) D Sorobetea et al.   Mucosal Immunology

A sticky end for gastrointestinal helminths; the role of the mucus barrier

(2018) C. Sharpe et al.   PARASITE IMMUNOLOGY

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the immune response by helminths: a role for serotonin?

(2018) Susan J. Wang et al.   BIOSCIENCE REPORTS

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche

(2018) Ysbrand M. Nusse et al.   NATURE

First Responders: Innate Immunity to Helminths

(2018) Juan M. Inclan-Rico et al.   TRENDS IN PARASITOLOGY

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

(2018) Katherine A Smith et al.   eLife

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

(2018) Moshe Biton et al.   CELL

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

(2018) Rick M. Maizels et al.   IMMUNITY

Helminth Infections Induce Tissue Tolerance Mitigating Immunopathology but Enhancing Microbial Pathogen Susceptibility

(2018) George S. Yap et al.   Frontiers in Immunology

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

(2017) Megan Osbourn et al.   IMMUNITY

Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity

(2017) J J Worthington et al.   Mucosal Immunology

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

(2017) Chris J. C. Johnston et al.   Nature Communications

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(2017) Paul J. Brindley et al.   PLoS Pathogens

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

Improved Swiss-rolling Technique for Intestinal Tissue Preparation for Immunohistochemical and Immunofluorescent Analyses

(2016) Agnieszka B. Bialkowska et al.   Jove-Journal of Visualized Experiments

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia

(2015) Michael J. Smout et al.   PLoS Pathogens

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

(2015) Chris J. C. Johnston et al.   Jove-Journal of Visualized Experiments

Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine

(2014) Boaz E Aronson et al.   BMC MOLECULAR BIOLOGY

Global numbers of infection and disease burden of soil transmitted helminth infections in 2010

(2014) Rachel L Pullan et al.   Parasites & Vectors

Adaptive Immunity Alters Distinct Host Feeding Pathways during Nematode Induced Inflammation, a Novel Mechanism in Parasite Expulsion

(2013) John J. Worthington et al.   PLoS Pathogens

IL-13-mediated immunological control of enterochromaffin cell hyperplasia and serotonin production in the gut

(2012) M Manocha et al.   Mucosal Immunology

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

(2012) Lisa A. Reynolds et al.   Seminars in Immunopathology

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

(2009) Michael J. Smout et al.   PLoS Pathogens

The intestinal epithelium: sensors to effectors in nematode infection

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