Immunity to gastrointestinal nematode infections

Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections

(2017) Chikako Shimokawa et al.   IMMUNITY

Diversity and functions of intestinal mononuclear phagocytes

(2017) T Joeris et al.   Mucosal Immunology

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation

(2017) Christoph S. N. Klose et al.   NATURE

Neuronal regulation of type 2 innate lymphoid cells via neuromedin U

(2017) Vânia Cardoso et al.   NATURE

Distinct DC subsets regulate adaptive Th1 and 2 responses during Trichuris muris infection

(2017) M. Demiri et al.   PARASITE IMMUNOLOGY

Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon

(2017) Johannes U. Mayer et al.   Nature Communications

PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less

(2017) Peter Hotez et al.   PLoS Neglected Tropical Diseases

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

(2017) Sumaira Z. Hasnain et al.   PLoS Pathogens

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

(2017) Yashaswini Kannan et al.   PLoS Pathogens

Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines

(2016) Leon P. McLean et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Eosinophils may play regionally disparate roles in influencing IgA+ plasma cell numbers during large and small intestinal inflammation

(2016) Ruth Forman et al.   BMC IMMUNOLOGY

Acute infection with the intestinal parasite Trichuris muris has long-term consequences on mucosal mast cell homeostasis and epithelial integrity

(2016) Daniel Sorobetea et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

ChronicTrichuris murisinfection alters hematopoiesis and causes IFN-γ-expressing T-cell accumulation in the mouse bone marrow

(2016) Alistair L. Chenery et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

(2016) Katarzyna M. Luda et al.   IMMUNITY

A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection

(2016) Rachel J Lundie et al.   IMMUNOLOGY AND CELL BIOLOGY

Critical Role for Interleukin-25 in Host Protective Th2 Memory Response against Heligmosomoides polygyrus bakeri

(2016) Chenlin Pei et al.   INFECTION AND IMMUNITY

Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection

(2016) Gang Chen et al.   INFECTION AND IMMUNITY

Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles

(2016) Lisa M. Connor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small intestinal eosinophils regulate Th17 cells by producing IL-1 receptor antagonist

(2016) Reiko Sugawara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013

(2016) Maigeng Zhou et al.   LANCET

Intestinal Batf3-dependent dendritic cells are required for optimal antiviral T-cell responses in adult and neonatal mice

(2016) T Sun et al.   Mucosal Immunology

Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response

(2016) S Joo et al.   Mucosal Immunology

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection

(2016) V S Pelly et al.   Mucosal Immunology

Eosinophils are required to suppress Th2 responses in Peyer’s patches during intestinal infection by nematodes

(2016) J Strandmark et al.   Mucosal Immunology

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

A tissue checkpoint regulates type 2 immunity

(2016) Steven J Van Dyken et al.   NATURE IMMUNOLOGY

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

TLR5 mediates CD172α+ intestinal lamina propria dendritic cell induction of Th17 cells

(2016) Han Liu et al.   Scientific Reports

Acidic mammalian chitinase is a proteases-resistant glycosidase in mouse digestive system

(2016) Misa Ohno et al.   Scientific Reports

Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection

(2016) Menno J. Oudhoff et al.   PLoS Pathogens

Surfactant Protein-D Is Essential for Immunity to Helminth Infection

(2016) Sumaiyya Thawer et al.   PLoS Pathogens

Hookworm infection

(2016) Alex Loukas et al.   Nature Reviews Disease Primers

Dendritic-cell expression ofShip1regulates Th2 immunity to helminth infection in mice

(2015) Matthew J. Gold et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy

(2015) Chun-Yu Chen et al.   IMMUNITY

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

(2015) Thibault Griseri et al.   IMMUNITY

Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses

(2015) Roxane Tussiwand et al.   IMMUNITY

The Interleukin-33-p38 Kinase Axis Confers Memory T Helper 2 Cell Pathogenicity in the Airway

(2015) Yusuke Endo et al.   IMMUNITY

Low-Dose Intestinal Trichuris muris Infection Alters the Lung Immune Microenvironment and Can Suppress Allergic Airway Inflammation

(2015) Alistair L. Chenery et al.   INFECTION AND IMMUNITY

Thymic stromal lymphopoietin signaling in CD4+ T cells is required for TH2 memory

(2015) Qun Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Migratory CD103+dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

(2015) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9–Producing T Cells in Acute Allergic Lung Inflammation

(2015) Estefania Claudio et al.   JOURNAL OF IMMUNOLOGY

The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD

(2015) J Cosín-Roger et al.   Mucosal Immunology

IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production

(2015) Y Jung et al.   Mucosal Immunology

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses

(2015) Timotheus Y F Halim et al.   NATURE IMMUNOLOGY

Innate immunological function of TH2 cells in vivo

(2015) Liying Guo et al.   NATURE IMMUNOLOGY

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

(2015) Peter C. Cook et al.   Nature Communications

CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

(2015) Emma C. Mackley et al.   Nature Communications

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

(2015) James P. Hewitson et al.   PLoS Pathogens

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair

(2015) Julia Esser-von Bieren et al.   PLoS Pathogens

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid

(2015) Hong-Hu Chen et al.   PLoS One

Batf3-dependent CD103+dendritic cells are major producers of IL-12 that drive local Th1 immunity againstLeishmania majorinfection in mice

(2014) María Martínez-López et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-25 exhibits disparate roles during Th2-cell differentiation versus effector function

(2014) Helen Mearns et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Eosinophils Promote Generation and Maintenance of Immunoglobulin-A-Expressing Plasma Cells and Contribute to Gut Immune Homeostasis

(2014) Van Trung Chu et al.   IMMUNITY

Chitin Activates Parallel Immune Modules that Direct Distinct Inflammatory Responses via Innate Lymphoid Type 2 and γδ T Cells

(2014) Steven J. Van Dyken et al.   IMMUNITY

Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation

(2014) Timotheus Y.F. Halim et al.   IMMUNITY

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

(2014) Christopher J. Oliphant et al.   IMMUNITY

Basophil-Derived Interleukin-4 Controls the Function of Natural Helper Cells, a Member of ILC2s, in Lung Inflammation

(2014) Yasutaka Motomura et al.   IMMUNITY

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

(2014) Kara J Filbey et al.   IMMUNOLOGY AND CELL BIOLOGY

A thymic stromal lymphopoietin–responsive dendritic cell subset mediates allergic responses in the upper airway mucosa

(2014) Guro R. Melum et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

(2014) Derek K. Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Goblet Cell-Derived Resistin-Like Molecule   Augments CD4+ T Cell Production of IFN-  and Infection-Induced Intestinal Inflammation

(2014) M. G. Nair et al.   JOURNAL OF IMMUNOLOGY

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

Dynamic Changes in Macrophage Activation and Proliferation during the Development and Resolution of Intestinal Inflammation

(2014) Matthew C. Little et al.   JOURNAL OF IMMUNOLOGY

CD326loCD103loCD11bloDermal Dendritic Cells Are Activated by Thymic Stromal Lymphopoietin during Contact Sensitization in Mice

(2014) Sotaro Ochiai et al.   JOURNAL OF IMMUNOLOGY

Eosinophils Mediate Protective Immunity against Secondary Nematode Infection

(2014) Lu Huang et al.   JOURNAL OF IMMUNOLOGY

Type 2 Innate Lymphoid Cells Drive CD4+ Th2 Cell Responses

(2014) A. S. Mirchandani et al.   JOURNAL OF IMMUNOLOGY

Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths

(2014) K Oeser et al.   Mucosal Immunology

A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

(2014) P Holmkvist et al.   Mucosal Immunology

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells

(2014) V Cerovic et al.   Mucosal Immunology

Global numbers of infection and disease burden of soil transmitted helminth infections in 2010

(2014) Rachel L Pullan et al.   Parasites & Vectors

Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells

(2014) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice

(2014) Ekta K Bhardwaj   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation

(2013) Scott E Levison et al.   BMC GENOMICS

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection

(2013) Paula Licona-Limón et al.   IMMUNITY

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity

(2013) Yosuke Kumamoto et al.   IMMUNITY

Control of T Helper 2 Responses by Transcription Factor IRF4-Dependent Dendritic Cells

(2013) Yan Gao et al.   IMMUNITY

Participation of MyD88 and Interleukin-33 as Innate Drivers of Th2 Immunity to Trichinella spiralis

(2013) Lisa K. Scalfone et al.   INFECTION AND IMMUNITY

Interleukin-25 (IL-25) Promotes Efficient Protective Immunity against Trichinella spiralis Infection by Enhancing the Antigen-Specific IL-9 Response

(2013) Pornpimon Angkasekwinai et al.   INFECTION AND IMMUNITY

IL-33–dependent induction of allergic lung inflammation by FcγRIII signaling

(2013) Melissa Y. Tjota et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The skin is an important bulwark of acquired immunity against intestinal helminths

(2013) Kazushige Obata-Ninomiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Heligmosomoides polygyrus bakeri Infection Activates Colonic Foxp3+ T Cells Enhancing Their Capacity To Prevent Colitis

(2013) L. Hang et al.   JOURNAL OF IMMUNOLOGY

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Type 2 innate lymphoid cells control eosinophil homeostasis

(2013) Jesse C. Nussbaum et al.   NATURE

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

A Unique Dermal Dendritic Cell Subset That Skews the Immune Response toward Th2

(2013) Ryuichi Murakami et al.   PLoS One

Eosinophils secrete IL-4 to facilitate liver regeneration

(2013) Y. P. S. Goh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection

(2013) William G. C. Horsnell et al.   PLoS Pathogens

Loss of the TGFβ-Activating Integrin αvβ8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type 2 Immunity

(2013) John J. Worthington et al.   PLoS Pathogens

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

(2013) Julia Esser-von Bieren et al.   PLoS Pathogens

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

The ‘Hygiene hypothesis’ and the sharp gradient in the incidence of autoimmune and allergic diseases between Russian Karelia and Finland

(2012) Anita Kondrashova et al.   APMIS

Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus

(2012) Henry J. McSorley et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epithelial Cell-Specific Act1 Adaptor Mediates Interleukin-25-Dependent Helminth Expulsion through Expansion of Lin−c-Kit+ Innate Cell Population

(2012) Zizhen Kang et al.   IMMUNITY

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

(2012) Marsha Wills-Karp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Colonic epithelial response to injury requires Myd88 signaling in myeloid cells

(2012) N P Malvin et al.   Mucosal Immunology

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Nippostrongylus-Induced Intestinal Hypercontractility Requires IL-4 Receptor Alpha-Responsiveness by T Cells in Mice

(2012) Saskia Schmidt et al.   PLoS One

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

(2012) M. R. Hepworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

(2012) L.-Y. Hung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

(2012) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

(2012) Lisa A. Reynolds et al.   Seminars in Immunopathology

Trichuris muris: a model of gastrointestinal parasite infection

(2012) Joanna E. Klementowicz et al.   Seminars in Immunopathology

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

(2012) Sumaira Z. Hasnain et al.   PLoS Neglected Tropical Diseases

IL-33-activated dendritic cells are critical for allergic airway inflammation

(2011) Anne-Gaëlle Besnard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Muc5ac: a critical component mediating the rejection of enteric nematodes

(2011) Sumaira Z. Hasnain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

(2011) K. Fujimoto et al.   JOURNAL OF IMMUNOLOGY

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

(2011) Mark C. Siracusa et al.   NATURE

Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

(2011) Hong-Erh Liang et al.   NATURE IMMUNOLOGY

Eosinophils are required for the maintenance of plasma cells in the bone marrow

(2011) Van Trung Chu et al.   NATURE IMMUNOLOGY

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

(2011) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris

(2011) R. BOWCUTT et al.   PARASITE IMMUNOLOGY

Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice

(2010) Tomohiro Yamada et al.   FASEB JOURNAL

Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

(2010) Sumaira Z. Hasnain et al.   GASTROENTEROLOGY

Colonic transcriptional profiling in resistance and susceptibility to trichuriasis

(2010) S. E. Levison et al.   INFLAMMATORY BOWEL DISEASES

CD11c depletion severely disrupts Th2 induction and development in vivo

(2010) Alexander T. Phythian-Adams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Arginase I Suppresses IL-12/IL-23p40-Driven Intestinal Inflammation during Acute Schistosomiasis

(2010) D. R. Herbert et al.   JOURNAL OF IMMUNOLOGY

Critical Role of IL-25 in Nematode Infection-Induced Alterations in Intestinal Function

(2010) A. Zhao et al.   JOURNAL OF IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection

(2010) M. SVENSSON et al.   PARASITE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

(2009) Betsy C. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Common  -Chain-Dependent Signals Confer Selective Survival of Eosinophils in the Murine Small Intestine

(2009) J. Carlens et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3

(2009) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

(2009) Tomohiro Yoshimoto et al.   NATURE IMMUNOLOGY

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

(2009) Caroline L Sokol et al.   NATURE IMMUNOLOGY

Depleted intestinal goblet cells and severe pathological changes in SCID mice infected withHeligmosomoides polygyrus

(2009) K. HASHIMOTO et al.   PARASITE IMMUNOLOGY

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

(2009) J. C. Massacand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyclonal and Specific Antibodies Mediate Protective Immunity against Enteric Helminth Infection

(2008) Kathy D. McCoy et al.   Cell Host & Microbe

Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages

(2008) Aiping Zhao et al.   GASTROENTEROLOGY

Neither interleukin-4 receptor α expression on CD4+T cells, or macrophages and neutrophils is required for protective immunity toTrichinella spiralis

(2008) Chesney E. Michels et al.   IMMUNOLOGY

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

(2008) S. Rausch et al.   INFECTION AND IMMUNITY

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

(2008) W. Brett Cherry et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

(2008) Elizabeth E. Forbes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

(2008) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE