Complement opsonization of nanoparticles: Differences between humans and preclinical species

Complement activation by drug carriers and particulate pharmaceuticals: Principles, challenges and opportunities

(2020) S. Moein Moghimi et al.   ADVANCED DRUG DELIVERY REVIEWS

Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood

(2020) Hanmant Gaikwad et al.   BIOCONJUGATE CHEMISTRY

A Pilot Study on the Safety of a Novel Antioxidant Nanoparticle Delivery System and Its Indirect Effects on Cytokine Levels in Four Dogs

(2020) Kelsey Robinson et al.   Frontiers in Veterinary Science

Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers

(2019) Lisa J. Schlein et al.   Frontiers in Oncology

Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55

(2019) Geoffrey Gifford et al.   JOURNAL OF CONTROLLED RELEASE

Naturally occurring cancers in pet dogs as pre-clinical models for cancer immunotherapy

(2019) Lidia Tarone et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

On the issue of transparency and reproducibility in nanomedicine

(2019) Hon S. Leong et al.   Nature Nanotechnology

Feraheme (Ferumoxytol) Is Recognized by Proinflammatory and Anti-inflammatory Macrophages via Scavenger Receptor Type AI/II

(2019) Guankui Wang et al.   MOLECULAR PHARMACEUTICS

C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes

(2018) Regina Tavano et al.   ACS Nano

Tanovea® for the treatment of lymphoma in dogs

(2018) Erik De Clercq   BIOCHEMICAL PHARMACOLOGY

Translational gaps in animal models of human infusion reactions to nanomedicines

(2018) S Moein Moghimi et al.   Nanomedicine

Roadmap and strategy for overcoming infusion reactions to nanomedicines

(2018) Janos Szebeni et al.   Nature Nanotechnology

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

(2018) Vivian P. Vu et al.   Nature Nanotechnology

First‐in‐Human Phase I Study of MBC‐11, a Novel Bone‐Targeted Cytarabine‐Etidronate Conjugate in Patients with Cancer‐Induced Bone Disease

(2018) Shawn Patrick Zinnen et al.   ONCOLOGIST

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

(2018) Mariana Gaya da Costa et al.   Frontiers in Immunology

Complement C3-dependent uptake of targeted liposomes into human macrophages, B cells, dendritic cells, neutrophils, and MDSCs

(2017) Alexandra Francian et al.   International Journal of Nanomedicine

Current and potential imaging applications of ferumoxytol for magnetic resonance imaging

(2017) Gerda B. Toth et al.   KIDNEY INTERNATIONAL

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Studies of Pig Complement: Measurement of Pig CH50, ACH50, and Components

(2016) R. Sakai et al.   TRANSPLANTATION PROCEEDINGS

Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking

(2016) Guankui Wang et al.   Frontiers in Immunology

Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake

(2015) Swetha Inturi et al.   ACS Nano

Complement C3 mediated targeting of liposomes to granulocytic myeloid derived suppressor cells

(2015) Max Kullberg et al.   Nanomedicine-Nanotechnology Biology and Medicine

High-Relaxivity Superparamagnetic Iron Oxide Nanoworms with Decreased Immune Recognition and Long-Circulating Properties

(2014) Guankui Wang et al.   ACS Nano

Mediation of a non-proteolytic activation of complement component C3 by phospholipid vesicles

(2014) Yvonne Klapper et al.   BIOMATERIALS

Inhibitor(s) of the classical complement pathway in mouse serum limit the utility of mice as experimental models of neuromyelitis optica

(2014) Julien Ratelade et al.   MOLECULAR IMMUNOLOGY

Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum

(2014) Nirmal K Banda et al.   Particle and Fibre Toxicology

Single-Walled Carbon Nanotube Surface Control of Complement Recognition and Activation

(2013) Alina J. Andersen et al.   ACS Nano

Direct Recognition of Superparamagnetic Nanocrystals by Macrophage Scavenger Receptor SR-AI

(2013) Ying Chao et al.   ACS Nano

Complement monitoring of Pluronic 127 gel and micelles: Suppression of copolymer-mediated complement activation by elevated serum levels of HDL, LDL, and apolipoproteins AI and B-100

(2013) Islam Hamad et al.   JOURNAL OF CONTROLLED RELEASE

Proteolysis of Complement Factors iC3b and C5 by the Serine Protease Prostate-Specific Antigen in Prostatic Fluid and Seminal Plasma

(2013) M. L. Manning et al.   JOURNAL OF IMMUNOLOGY

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

(2013) Gareth R Howell et al.   Journal of Neuroinflammation

Recognition of Dextran–Superparamagnetic Iron Oxide Nanoparticle Conjugates (Feridex) via Macrophage Scavenger Receptor Charged Domains

(2012) Ying Chao et al.   BIOCONJUGATE CHEMISTRY

The complotype: dictating risk for inflammation and infection

(2012) Claire L. Harris et al.   TRENDS IN IMMUNOLOGY

Material properties in complement activation

(2011) S. Moein Moghimi et al.   ADVANCED DRUG DELIVERY REVIEWS

Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk

(2011) M. Heurich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Polymer Architecture Mediates Switching of Complement Activation Pathways at the Nanosphere−Serum Interface: Implications for Stealth Nanoparticle Engineering

(2010) Islam Hamad et al.   ACS Nano

Curvature of Synthetic and Natural Surfaces Is an Important Target Feature in Classical Pathway Complement Activation

(2010) Martin Bjerregård Pedersen et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Preparing serum for functional complement assays

(2009) P.J. Lachmann   JOURNAL OF IMMUNOLOGICAL METHODS

Pathway-specific complement activity in pigs evaluated with a human functional complement assay

(2009) Bodil Salvesen et al.   MOLECULAR IMMUNOLOGY

Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles

(2008) Marina A. Dobrovolskaia et al.   Nanomedicine-Nanotechnology Biology and Medicine

The tick-over theory revisited: Formation and regulation of the soluble alternative complement C3 convertase (C3(H2O)Bb)

(2007) Fredrik Bexborn et al.   MOLECULAR IMMUNOLOGY