A Pilot Study on the Safety of a Novel Antioxidant Nanoparticle Delivery System and Its Indirect Effects on Cytokine Levels in Four Dogs

Evaluating accessibility of intravenously administered nanoparticles at the lesion site in rat and pig contusion models of spinal cord injury

(2019) Yue Gao et al.   JOURNAL OF CONTROLLED RELEASE

Dose‐dependent pruritogenic and inflammatory effects of intradermal injections of histamine, compound 48/80 and anti‐canine IgE in healthy dogs

(2019) Frane Banovic et al.   VETERINARY DERMATOLOGY

Validation of the Prescreening Intradermal Skin Test for Predicting Hypersensitivity to Iodinated Contrast Media: A Prospective Study with ICM Challenge

(2019) Ji-Hyang Lee et al.   Journal of Allergy and Clinical Immunology-In Practice

The anti-inflammatory effect of topical tofacitinib on immediate and late-phase cutaneous allergic reactions in dogs: a placebo-controlled pilot study

(2018) Amanda Blubaugh et al.   VETERINARY DERMATOLOGY

The role of diffusion tensor imaging as an objective tool for the assessment of motor function recovery after paraplegia in a naturally-occurring large animal model of spinal cord injury

(2018) Adriano Wang-Leandro et al.   Journal of Translational Medicine

Roadmap and strategy for overcoming infusion reactions to nanomedicines

(2018) Janos Szebeni et al.   Nature Nanotechnology

Drug-Induced Pseudoallergy: A Review of the Causes and Mechanisms

(2017) Bo Zhang et al.   PHARMACOLOGY

Proportion recovery and times to ambulation for non-ambulatory dogs with thoracolumbar disc extrusions treated with hemilaminectomy or conservative treatment: A systematic review and meta-analysis of case-series studies

(2017) L. Langerhuus et al.   VETERINARY JOURNAL

Cytokine Concentrations Measured by Multiplex Assays in Canine Peripheral Blood Samples

(2017) Kristen R. Richter et al.   VETERINARY PATHOLOGY

A Review of Stem Cell Therapy for Spinal Cord Injury: Large Animal Models and the Frontier in Humans

(2017) Brandon C. Gabel et al.   World Neurosurgery

Traumatic spinal cord injury

(2017) Christopher S. Ahuja et al.   Nature Reviews Disease Primers

Tissue plasminogen activator followed by antioxidant-loaded nanoparticle delivery promotes activation/mobilization of progenitor cells in infarcted rat brain

(2016) Marianne Petro et al.   BIOMATERIALS

Macrophage polarization: a key event in the secondary phase of acute spinal cord injury

(2016) Xiangyi Kong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Systematic Review and Meta-Analysis

(2016) Nathan Evaniew et al.   JOURNAL OF NEUROTRAUMA

Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model

(2016) Joshua A. Jackman et al.   Nanomedicine-Nanotechnology Biology and Medicine

Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission

(2016) Noa Safra et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Inflammogenesis of Secondary Spinal Cord Injury

(2016) M. Akhtar Anwar et al.   Frontiers in Cellular Neuroscience

Traumatic Spinal Cord Injury in the United States, 1993-2012

(2015) Nitin B. Jain et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Propensity Score-Matched Cohort Study from a Canadian Multi-Center Spinal Cord Injury Registry

(2015) Nathan Evaniew et al.   JOURNAL OF NEUROTRAUMA

A Placebo-Controlled, Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation

(2015) N.J. Olby et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies

(2015) Cristina Fornaguera et al.   Nanoscale

Complement System Part I – Molecular Mechanisms of Activation and Regulation

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Features of complement activation-related pseudoallergy to liposomes with different surface charge and PEGylation: Comparison of the porcine and rat responses

(2014) László Dézsi et al.   JOURNAL OF CONTROLLED RELEASE

Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals

(2014) Janos Szebeni   MOLECULAR IMMUNOLOGY

Clinical value of radiocontrast media skin tests as a prescreening and diagnostic tool in hypersensitivity reactions

(2013) Sae-Hoon Kim et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

From basics to clinical: A comprehensive review on spinal cord injury

(2013) Nuno A. Silva et al.   PROGRESS IN NEUROBIOLOGY

The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate

(2013) B B Lee et al.   SPINAL CORD

Unexpected Hematologic Effects of Biotherapeutics in Nonclinical Species and in Humans

(2013) Nancy E. Everds et al.   TOXICOLOGIC PATHOLOGY

Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress

(2013) A Singhal et al.   Cell Death & Disease

A porcine model of complement-mediated infusion reactions to drug carrier nanosystems and other medicines

(2012) János Szebeni et al.   ADVANCED DRUG DELIVERY REVIEWS

Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: Prediction and prevention

(2011) Janos Szebeni et al.   ADVANCED DRUG DELIVERY REVIEWS

Antioxidant therapies in traumatic brain and spinal cord injury

(2011) Mona Bains et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Microglial Contribution to Secondary Injury Evaluated in a Large Animal Model of Human Spinal Cord Trauma

(2011) Theda Marie Anne Boekhoff et al.   JOURNAL OF NEUROTRAUMA

Quantitative Magnetic Resonance Imaging Characteristics

(2011) Theda M. Boekhoff et al.   JOURNAL OF SPINAL DISORDERS & TECHNIQUES

Advances in stroke therapy

(2011) Hayder Jaffer et al.   Drug Delivery and Translational Research

Incidence of Spinal Cord Injury Worldwide: A Systematic Review

(2010) M.E.L. van den Berg et al.   NEUROEPIDEMIOLOGY

Effect of a novel topical diester glucocorticoid spray on immediate- and late-phase cutaneous allergic reactions in Maltese-beagle atopic dogs: a placebo-controlled study

(2010) Petra Bizikova et al.   VETERINARY DERMATOLOGY

Skin testing in patients with hypersensitivity reactions to iodinated contrast media - a European multicenter study

(2009) K. Brockow et al.   ALLERGY

Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury

(2009) Maram K. Reddy et al.   FASEB JOURNAL

Elevated serum cytokines during human anaphylaxis: Identification of potential mediators of acute allergic reactions

(2009) Shelley F. Stone et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Activity of pulmonary intravascular macrophages in cats and dogs with and without adult Dirofilaria immitis

(2008) A.R. Dillon et al.   VETERINARY PARASITOLOGY