Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer’s Disease

Alzheimer's disease

(2021) Philip Scheltens et al.   LANCET

Redox Effects of Molecular Hydrogen and Its Therapeutic Efficacy in the Treatment of Neurodegenerative Diseases

(2021) Md. Habibur Rahman et al.   Processes

Astrocytic Propagation of Tau in the Context of Alzheimer's Disease

(2021) Rebecca M. Fleeman et al.   Frontiers in Cellular Neuroscience

Therapeutic Potential of Natural Products in Treating Neurodegenerative Disorders and Their Future Prospects and Challenges

(2021) Md. Habibur Rahman et al.   MOLECULES

The Human Hippocampus in Parkinson’s Disease: An Integrative Stereological and Proteomic Study

(2021) Sandra Villar-Conde et al.   Journal of Parkinsons Disease

Protein transmission in neurodegenerative disease

(2020) Chao Peng et al.   Nature Reviews Neurology

SWATH-MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer’s disease

(2020) Sun Ah Park et al.   Scientific Reports

Differential Atrophy in the Hippocampal Subfield Volumes in Four Types of Mild Dementia

(2020) Lin Huang et al.   Frontiers in Neuroscience

The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases

(2020) Isabel Ubeda-Bañon et al.   Translational Neurodegeneration

Mechanistic Insights into the Role of Molecular Chaperones in Protein Misfolding Diseases: From Molecular Recognition to Amyloid Disassembly

(2020) Rubén Hervás et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers

(2020) Ryan P. Kreiser et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beyond the neuron–cellular interactions early in Alzheimer disease pathogenesis

(2019) Christopher M. Henstridge et al.   NATURE REVIEWS NEUROSCIENCE

BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes

(2019) Changyi Ji et al.   Autophagy

The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

(2019) Amaia M Arranz et al.   LANCET NEUROLOGY

Extracellular Monomeric Tau Is Internalized by Astrocytes

(2019) Juan Ramón Perea et al.   Frontiers in Neuroscience

Neuron-Glia Signaling in Synapse Elimination

(2019) Daniel K. Wilton et al.   Annual Review of Neuroscience

Human amyloid-β enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization

(2019) Cristina M. Pedrero-Prieto et al.   Alzheimers Research & Therapy

Intersection of pathological tau and microglia at the synapse

(2019) Thomas Vogels et al.   Acta Neuropathologica Communications

Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases

(2019) Anastasiia Bohush et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The proteome of the dentate terminal zone of the perforant path indicates presynaptic impairment in Alzheimer disease

(2019) Hazal Haytural et al.   MOLECULAR & CELLULAR PROTEOMICS

Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

(2019) Sneha Narasimhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy

(2018) Thomas E Cope et al.   BRAIN

Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

(2018) Claudia Campanella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading

(2018) Heidi Martini-Stoica et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Clinical validity of medial temporal atrophy as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

(2017) Mara ten Kate et al.   NEUROBIOLOGY OF AGING

Hsp90 and FKBP51: complex regulators of psychiatric diseases

(2017) Marangelie Criado-Marrero et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease

(2017) Elisabeth Stürner et al.   Frontiers in Molecular Neuroscience

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

(2017) Rachel E. Lackie et al.   Frontiers in Neuroscience

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

(2016) Elisabeth Sanchez-Mejias et al.   ACTA NEUROPATHOLOGICA

Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease

(2016) David C. Hondius et al.   Alzheimers & Dementia

Quantitative protein profiling of hippocampus during human aging

(2016) Benhong Xu et al.   NEUROBIOLOGY OF AGING

Atrophy of hippocampal subfields and adjacent extrahippocampal structures in dementia with Lewy bodies and Alzheimer's disease

(2016) Stefano Delli Pizzi et al.   NEUROBIOLOGY OF AGING

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

(2015) D. Tromp et al.   AGEING RESEARCH REVIEWS

Emerging Concepts in Alzheimer's Disease

(2015) Harry V. Vinters   Annual Review of Pathology-Mechanisms of Disease

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

BAG3 facilitates the clearance of endogenous tau in primary neurons

(2015) Zhinian Lei et al.   NEUROBIOLOGY OF AGING

SWATH analysis of the synaptic proteome in Alzheimer's disease

(2015) Rachel Yoon Kyung Chang et al.   NEUROCHEMISTRY INTERNATIONAL

Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer’s disease

(2015) Jae Ho Kim et al.   Scientific Reports

Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization

(2015) Sook-Jeong Lee et al.   Molecular Brain

Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease

(2014) Laura J Blair et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Heat Shock Protein 90 in Alzheimer’s Disease

(2014) Jiang-Rong Ou et al.   Biomed Research International

Chaperone-mediated autophagy: roles in neurodegeneration

(2014) Gang Wang et al.   Translational Neurodegeneration

Heat shock protein 90 in neurodegenerative diseases

(2012) Wenjie Luo et al.   Molecular Neurodegeneration

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins

(2011) Martin Gamerdinger et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases

(2011) K. Seidel et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY