Inhibition of TLR4 prevents hippocampal hypoxic-ischemic injury by regulating ferroptosis in neonatal rats

The circadian clock protects against ferroptosis-induced sterile inflammation

(2020) Yang Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs)

(2020) Yaqin Cao et al.   Artificial Cells Nanomedicine and Biotechnology

Long non-coding RNA NEAT1 binds to microRNA-339-5p to increase HOXA1 and alleviate ischemic brain damage in neonatal mice

(2020) Jing Zhao et al.   Molecular Therapy-Nucleic Acids

Distinct cellular mediators drive the Janus faces of toll-like receptor 4 regulation of network excitability which impacts working memory performance after brain injury

(2020) Akshata A. Korgaonkar et al.   BRAIN BEHAVIOR AND IMMUNITY

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

(2020) Xuexian Fang et al.   CIRCULATION RESEARCH

IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model

(2020) Juan Huang et al.   Journal of Neuroinflammation

Methylation in HT22 cells and primary hippocampal neurons with and without isoflurane exposure

(2020) Stefanie Klenke et al.   BMC Anesthesiology

Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway

(2020) Zhixian Gou et al.   BRAIN RESEARCH BULLETIN

Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE

(2020) Xiao Hu et al.   Oxidative Medicine and Cellular Longevity

Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes

(2020) Dan Li et al.   Nutrients

Role of toll-like receptor 4 in the regulation of the cell death pathway and neuroinflammation

(2019) Yafei Li et al.   BRAIN RESEARCH BULLETIN

Early TLR4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodents and human brain ischemia models

(2019) E. Parada et al.   BRITISH JOURNAL OF PHARMACOLOGY

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

(2019) Bo Chu et al.   NATURE CELL BIOLOGY

NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis

(2019) Liyan Hou et al.   TOXICOLOGY

MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

(2019) Bo Li et al.   Cellular & Molecular Immunology

Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis

(2019) Shinya Tsurusaki et al.   Cell Death & Disease

Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity

(2019) Zhen Tang et al.   EXPERIMENTAL NEUROLOGY

TRPV1 translocated to astrocytic membrane to promote migration and inflammatory infiltration thus promotes epilepsy after hypoxic ischemia in immature brain

(2019) Xin Wang et al.   Journal of Neuroinflammation

High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia

(2019) Yanyan Sun et al.   Frontiers in Cellular Neuroscience

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

(2018) Jianping Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Resistin inhibits neuronal autophagy through Toll-like receptor 4

(2018) Jie Miao et al.   JOURNAL OF ENDOCRINOLOGY

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice

(2018) Bao-Shu Xie et al.   CNS Neuroscience & Therapeutics

Intracellular inflammatory and antioxidant pathways in postmortem frontal cortex of subjects with major depression: effect of antidepressants

(2018) David Martín-Hernández et al.   Journal of Neuroinflammation

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

Ellagic acid attenuates streptozocin induced diabetic nephropathy via the regulation of oxidative stress and inflammatory signaling

(2018) Benhong Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice

(2017) Xiaolong Yao et al.   JOURNAL OF NEUROIMMUNOLOGY

Effects of the TLR4 signaling pathway on apoptosis of neuronal cells in diabetes mellitus complicated with cerebral infarction in a rat model

(2017) Chao Li et al.   Scientific Reports

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury

(2015) Ying Li et al.   NEUROBIOLOGY OF DISEASE

p38MAPK/p53-Mediated Bax induction contributes to neurons degeneration in rotenone-induced cellular and rat models of Parkinson’s disease

(2013) Feng Wu et al.   NEUROCHEMISTRY INTERNATIONAL