High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia

Developmental differences in microglia morphology and gene expression during normal brain development and in response to hypoxia-ischemia

(2019) Pelin Cengiz et al.   NEUROCHEMISTRY INTERNATIONAL

L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice

(2019) Xin Zhou et al.   Frontiers in Molecular Neuroscience

The Role of High Mobility Group Box 1 in Ischemic Stroke

(2019) Yingze Ye et al.   Frontiers in Cellular Neuroscience

Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats

(2019) Meray Serdar et al.   Frontiers in Cellular Neuroscience

Natural products as a potential modulator of microglial polarization in neurodegenerative diseases

(2019) Xin Jin et al.   PHARMACOLOGICAL RESEARCH

Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

(2019) Eduardo Farias Sanches et al.   Frontiers in Physiology

Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization

(2018) Tielei Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High mobility group box-1 (HMGB1) is increased in injured mouse spinal cord and can elicit neurotoxic inflammation

(2018) Kristina A. Kigerl et al.   BRAIN BEHAVIOR AND IMMUNITY

Glycyrrhizin ameliorates inflammatory pain by inhibiting microglial activation-mediated inflammatory response via blockage of the HMGB1-TLR4-NF-kB pathway

(2018) Xiaojuan Sun et al.   EXPERIMENTAL CELL RESEARCH

High-mobility group box 1 in Parkinson's disease: from pathogenesis to therapeutic approaches

(2018) Efthalia Angelopoulou et al.   JOURNAL OF NEUROCHEMISTRY

Association of circulating blood HMGB1 levels with ischemic stroke: a systematic review and meta-analysis

(2018) Kai Le et al.   NEUROLOGICAL RESEARCH

High-mobility group box 1 protein (HMGB1) operates as an alarmin outside as well as inside cells

(2018) Ulf Andersson et al.   SEMINARS IN IMMUNOLOGY

Time-Course Changes and New Expressions of MIP-3α and Its Receptor, CCR6, in the Gerbil Hippocampal CA1 Area Following Transient Global Cerebral Ischemia

(2018) Joon Ha Park et al.   NEUROCHEMICAL RESEARCH

HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

(2018) Yam Nath Paudel et al.   Frontiers in Neuroscience

High-mobility group box-1 translocation and release after hypoxic ischemic brain injury in neonatal rats

(2018) Xiaodi Chen et al.   EXPERIMENTAL NEUROLOGY

Location, Location, Location: Appraising the Pleiotropic Function of HMGB1 in Fetal Brain

(2017) Martin G. Frasch et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Biology of Microglia in the Developing Brain

(2017) Charanjit Kaur et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

25 years of research on global asphyxia in the immature rat brain

(2017) M. Barkhuizen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

HMGB1 Translocation After Ischemia in the Ovine Fetal Brain

(2016) Jiyong Zhang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming

(2016) Laura K. Fonken et al.   JOURNAL OF NEUROSCIENCE

High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial

(2016) Y. W. Wu et al.   PEDIATRICS

Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats

(2016) Niccolò Terrando et al.   Frontiers in Immunology

Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia

(2015) Takashi Umekawa et al.   GLIA

Selective modulation of microglia polarization to M2 phenotype for stroke treatment

(2015) Cong-Yuan Xia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neuroinflammation and Neuroimmune Dysregulation after Acute Hypoxic-Ischemic Injury of Developing Brain

(2015) Utpal S. Bhalala et al.   Frontiers in Pediatrics

Early release of high-mobility group box 1 (HMGB1) from neurons in experimental subarachnoid hemorrhage in vivo and in vitro

(2014) Qing Sun et al.   Journal of Neuroinflammation

Delayed and Prolonged Local Brain Hypothermia Combined with Decompressive Craniectomy: A Novel Therapeutic Strategy That Modulates Glial Dynamics

(2014) Jong-Heon Kim et al.   Experimental Neurobiology

Age-Dependent Microglial Activation in Immature Brains After Hypoxia- Ischemia

(2013) Peter Ferrazzano et al.   CNS & Neurological Disorders-Drug Targets

Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep

(2013) Reint K Jellema et al.   Journal of Neuroinflammation

Microglia during development and aging

(2013) G. Jean Harry   PHARMACOLOGY & THERAPEUTICS

Microglia Phenotype Diversity

(2011) M. Olah et al.   CNS & Neurological Disorders-Drug Targets

Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain

(2011) Keiko Ohsawa et al.   GLIA

Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice

(2011) Simone E. Thal et al.   NEUROSCIENCE LETTERS

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

(2011) Jiyong Zhang et al.   STROKE

HMGB1: Roles in base excision repair and related function

(2010) Yuan Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology