TRPV1 translocated to astrocytic membrane to promote migration and inflammatory infiltration thus promotes epilepsy after hypoxic ischemia in immature brain

TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI)

(2019) Xing-Liang Yang et al.   Journal of Neuroinflammation

TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice

(2019) Zhouqing Wang et al.   Cell Death & Disease

Role of calcium permeable channels in dendritic cell migration

(2018) Pablo J Sáez et al.   CURRENT OPINION IN IMMUNOLOGY

Inflammation and Epilepsy: Preclinical Findings and Potential Clinical Translation

(2018) Gaetano Terrone et al.   CURRENT PHARMACEUTICAL DESIGN

Manganese exposure facilitates microglial JAK2-STAT3 signaling and consequent secretion of TNF-a and IL-1β to promote neuronal death

(2018) Lifeng Yin et al.   NEUROTOXICOLOGY

TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain

(2018) Miguel Ortíz-Rentería et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy

(2018) Ismail S. Zaitoun et al.   Scientific Reports

Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes

(2018) Matthew Neal et al.   GLIA

Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo — in search of potential anti-epileptogenic strategies for temporal lobe epilepsy

(2018) C. M. Drion et al.   Journal of Neuroinflammation

A Review on Potential Involvement of TRPV1 Channels in Ischemia–Reperfusion Injury

(2017) Puneet Kaur Randhawa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Role of Neuroinflammation in Evolution of Childhood Epilepsy

(2017) Sookyong Koh   JOURNAL OF CHILD NEUROLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus

(2017) Joaquin I. Hurtado-Zavala et al.   Nature Communications

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

(2017) Maria Cristina Marrone et al.   Nature Communications

Direct Anandamide Activation of TRPV1 Produces Divergent Calcium and Current Responses

(2017) Axel J. Fenwick et al.   Frontiers in Molecular Neuroscience

TRPA1 Channels Modify TRPV1-Mediated Current Responses in Dorsal Root Ganglion Neurons

(2017) Takayoshi Masuoka et al.   Frontiers in Physiology

Neuroprotective Effects of Annexin A1 Tripeptide after Deep Hypothermic Circulatory Arrest in Rats

(2017) Zhiquan Zhang et al.   Frontiers in Immunology

Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions

(2017) Marta Sidoryk-Wegrzynowicz et al.   Acta Neuropathologica Communications

L-type voltage-operated calcium channels contribute to astrocyte activationIn vitro

(2016) Veronica T. Cheli et al.   GLIA

Microglia-Neuron Communication in Epilepsy

(2016) Ukpong B. Eyo et al.   GLIA

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage

(2016) Mariya Hristova et al.   JOURNAL OF NEUROCHEMISTRY

Glia as drivers of abnormal neuronal activity

(2016) Stefanie Robel et al.   NATURE NEUROSCIENCE

Annexin A1 translocates to nucleus and promotes the expression of pro-inflammatory cytokines in a PKC-dependent manner after OGD/R

(2016) Baoming Zhao et al.   Scientific Reports

Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity

(2016) R. Ramírez-Barrantes et al.   NEURAL PLASTICITY

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Connexin 43 stabilizes astrocytes in a stroke-like milieu to facilitate neuronal recovery

(2015) Le-yu Wu et al.   ACTA PHARMACOLOGICA SINICA

A pathophysiological role of TRPV1 in ischemic injury after transient focal cerebral ischemia in mice

(2015) Jun Miyanohara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRPV1 promotes repetitive febrile seizures by pro-inflammatory cytokines in immature brain

(2015) Wen-Xian Huang et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

(2015) Samia Habbas et al.   CELL

Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models

(2015) Melissa J. Benson et al.   EPILEPSIA

Sodium-Calcium Exchanger 1 Regulates Epithelial Cell Migration via Calcium-dependent Extracellular Signal-regulated Kinase Signaling

(2015) Sona Lakshme Balasubramaniam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

(2015) Halima Amhaoul et al.   NEUROBIOLOGY OF DISEASE

Involvement of apoptosis and calcium accumulation through TRPV1 channels in neurobiology of epilepsy

(2015) M. Nazıroğlu et al.   NEUROSCIENCE

Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain

(2015) Fatemeh Saffarzadeh et al.   SYNAPSE

Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration

(2014) Karen W. Ho et al.   GLIA

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

(2014) Milos Pekny et al.   PHYSIOLOGICAL REVIEWS

Inflammatory responses in hypoxic ischemic encephalopathy

(2013) Fudong Liu et al.   ACTA PHARMACOLOGICA SINICA

Role of TRPV1 in susceptibility to PTZ-induced seizure following repeated hyperthermia challenges in neonatal mice

(2013) Wei-Lin Kong et al.   EPILEPSY & BEHAVIOR

Ionic Transporter Activity in Astrocytes, Microglia, and Oligodendrocytes During Brain Ischemia

(2013) Lucio Annunziato et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery

(2013) Selma O Algra et al.   Journal of Neuroinflammation

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

mTORC2 controls actin polymerization required for consolidation of long-term memory

(2013) Wei Huang et al.   NATURE NEUROSCIENCE

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Childhood Outcomes after Hypothermia for Neonatal Encephalopathy

(2012) Seetha Shankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammation in epilepsy: Clinical observations

(2011) Eleonora Aronica et al.   EPILEPSIA

Protein localization in disease and therapy

(2011) M.-C. Hung et al.   JOURNAL OF CELL SCIENCE

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

Cellular injury and neuroinflammation in children with chronic intractable epilepsy

(2009) Jieun Choi et al.   Journal of Neuroinflammation

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

(2009) Georgina S. Butler et al.   NATURE REVIEWS DRUG DISCOVERY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interaction with Phosphoinositides Confers Adaptation onto the TRPV1 Pain Receptor

(2009) Jing Yao et al.   PLOS BIOLOGY

Inflammatory Cytokines in Acute Ischemic Stroke

(2008) Antonino Tuttolomondo et al.   CURRENT PHARMACEUTICAL DESIGN

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE