Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation

Quantitative proteome comparison of human hearts with those of model organisms

(2021) Nora Linscheid et al.   PLOS BIOLOGY

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

(2020) Lorna R. Fiedler et al.   Cell Stem Cell

Clinical features of deaths in the novel coronavirus epidemic in China

(2020) Char Leung   REVIEWS IN MEDICAL VIROLOGY

Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research

(2020) John Sebastian Sigmon et al.   GENETICS

Four Core Genotypes and XY* mouse models: Update on impact on SABV research

(2020) Arthur P. Arnold   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Sex Differences in the Prevalence of, and Trends in, Cardiovascular Risk Factors, Treatment, and Control in the United States, 2001 to 2016

(2019) Sanne A.E. Peters et al.   CIRCULATION

A strategic research alliance: Turner syndrome and sex differences

(2019) Adrianna K. San Roman et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

The mouse as a model of fundamental concepts related to Turner syndrome

(2019) Arthur P. Arnold   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

High-Diversity Mouse Populations for Complex Traits

(2019) Michael C. Saul et al.   TRENDS IN GENETICS

Conservation, acquisition, and functional impact of sex-biased gene expression in mammals

(2019) Sahin Naqvi et al.   SCIENCE

Gender Differences in Cardiac Hypertrophy

(2019) Jian Wu et al.   Journal of Cardiovascular Translational Research

Conservation and divergence of protein pathways in the vertebrate heart

(2019) Joel D. Federspiel et al.   PLOS BIOLOGY

Muscle metabolism and atrophy: let’s talk about sex

(2019) Megan E. Rosa-Caldwell et al.   Biology of Sex Differences

Hepatic gene expression variations in response to high-fat diet-induced impaired glucose tolerance using RNAseq analysis in collaborative cross mouse population

(2019) H. J. Abu-Toamih Atamni et al.   MAMMALIAN GENOME

Congenital Heart Disease and Women’s Health Across the Life Span: Focus on Reproductive Issues

(2019) Kim Haberer et al.   CANADIAN JOURNAL OF CARDIOLOGY

What the Women's Health Initiative has taught us about menopausal hormone therapy

(2018) Rebecca C. Chester et al.   CLINICAL CARDIOLOGY

Of mice and men: the host response to influenza virus infection

(2018) Heike Kollmus et al.   MAMMALIAN GENOME

Epigenetic regulation of male fate commitment from an initially bipotential system

(2018) S. Alexandra Garcia-Moreno et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Corrigendum: Landscape of X chromosome inactivation across human tissues

(2018) Taru Tukiainen et al.   NATURE

CHD4 and the NuRD complex directly control cardiac sarcomere formation

(2018) Caralynn M. Wilczewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Collaborative Cross mouse model for dissecting genetic susceptibility to infectious diseases

(2018) Hanifa Abu Toamih Atamni et al.   MAMMALIAN GENOME

Sex Chromosome Effects on Male–Female Differences in Mammals

(2018) Daniel M. Snell et al.   CURRENT BIOLOGY

Sexual dimorphism in SLE: above and beyond sex hormones

(2018) E.A.A. Christou et al.   LUPUS

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Nature and implications of sex differences in AD pathology

(2018) Rosha Babapour Mofrad et al.   Nature Reviews Neurology

Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse

(2018) Cathleen John et al.   Frontiers in Endocrinology

Adult congenital heart disease in Greece: Preliminary data from the CHALLENGE registry

(2017) G. Giannakoulas et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection

(2017) Rudragouda Channappanavar et al.   JOURNAL OF IMMUNOLOGY

Estrogen alone and health outcomes in black women by African ancestry

(2017) Rowan T. Chlebowski et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

(2017) Sheng Chih Jin et al.   NATURE GENETICS

Mechanistic Pathways of Sex Differences in Cardiovascular Disease

(2017) Vera Regitz-Zagrosek et al.   PHYSIOLOGICAL REVIEWS

Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation

(2017) Lun Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Y chromosome’s roles in sex differences in disease

(2017) Arthur P. Arnold   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis

(2017) Leslie Kennedy et al.   PLoS Genetics

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

(2017) Rachael J. Werner et al.   Biology of Sex Differences

Host genetic background influences diverse neurological responses to viral infection in mice

(2017) Candice L. Brinkmeyer-Langford et al.   Scientific Reports

Cardiovascular Disease in Women

(2016) Mariana Garcia et al.   CIRCULATION RESEARCH

The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease

(2016) Christa L. Blenck et al.   CIRCULATION RESEARCH

Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease

(2016) Christine Maric-Bilkan et al.   HYPERTENSION

Defining the consequences of genetic variation on a proteome-wide scale

(2016) Joel M. Chick et al.   NATURE

A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases

(2016) Yun Liang et al.   NATURE IMMUNOLOGY

Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation

(2016) Julian R. Homburger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues

(2016) Paul S. Burgoyne et al.   Biology of Sex Differences

Diet and sex modify exercise and cardiac adaptation in the mouse

(2015) John P. Konhilas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Tetralogy of Fallot and Hypoplastic Left Heart Syndrome – Complex Clinical Phenotypes Meet Complex Genetic Networks

(2015) Harald Lahm et al.   CURRENT GENOMICS

Women, the menopause, hormone replacement therapy and coronary heart disease

(2015) Thomas F. Whayne et al.   CURRENT OPINION IN CARDIOLOGY

Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development

(2015) K. M. Dorr et al.   DEVELOPMENT

Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium

(2015) Danielle A. Fontaine et al.   DIABETES

X-chromosome inactivation and escape

(2015) CHRISTINE M. DISTECHE et al.   JOURNAL OF GENETICS

Informatics resources for the Collaborative Cross and related mouse populations

(2015) Andrew P. Morgan et al.   MAMMALIAN GENOME

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload

(2014) Georgios Kararigas et al.   EUROPEAN JOURNAL OF HEART FAILURE

Sexual dimorphism in obesity-mediated left ventricular hypertrophy

(2013) Christian Böhm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Collaborative Cross: A Recombinant Inbred Mouse Population for the Systems Genetic Era

(2013) D. W. Threadgill et al.   ILAR JOURNAL

Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart

(2013) Ana Maria Queirós et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Ten Years of the Collaborative Cross

(2012) David W. Threadgill et al.   GENETICS

Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Sex/Gender Differences in Cardiovascular Disease Prevention

(2011) Lori Mosca et al.   CIRCULATION

Sex-Based Differences in Susceptibility to Respiratory and Systemic Pneumococcal Disease in Mice

(2011) Aras Kadioglu et al.   JOURNAL OF INFECTIOUS DISEASES

Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women—2011 Update

(2011) Lori Mosca et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Gender differences in β-adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula

(2010) Melissa R. Dent et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition

(2010) Daniel W. Bellott et al.   NATURE

Why Sex Matters: Brain Size Independent Differences in Gray Matter Distributions between Men and Women

(2009) E. Luders et al.   JOURNAL OF NEUROSCIENCE

Revealing Global Regulatory Perturbations across Human Cancers

(2009) Hani Goodarzi et al.   MOLECULAR CELL

Sex-related changes in cardiac function following myocardial infarction in mice

(2008) Krystyna M. Shioura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sex-specific pathways in early cardiac response to pressure overload in mice

(2008) Henning Witt et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME

Shared Genetic Causes of Cardiac Hypertrophy in Children and Adults

(2008) Hiroyuki Morita et al.   NEW ENGLAND JOURNAL OF MEDICINE